Topiramate in Migraine Prevention: A 2016 Perspective

Use of computer simulations to test the concept of dose forgiveness in the era of extended-release (XR) drugs

(2016) John M. Pellock et al.   EPILEPSY & BEHAVIOR

Direct and Indirect Costs of Chronic and Episodic Migraine in the United States: A Web-Based Survey

(2016) Andrew Messali et al.   HEADACHE

Alkali replacement raises urinary citrate excretion in patients with topiramate-induced hypocitraturia

(2015) R. Allan Jhagroo et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacokinetic-pharmacodynamic modelling of intravenous and oral topiramate and its effect on phonemic fluency in adult healthy volunteers

(2015) Ghada F. Ahmed et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Modified-Release Formulations of Second-Generation Antiepileptic Drugs: Pharmacokinetic and Clinical Aspects

(2015) Gail D. Anderson et al.   CNS DRUGS

Pharmacokinetic simulations of topiramate plasma concentrations following dosing irregularities with extended-release vs. immediate-release formulations

(2015) Scott T. Brittain et al.   EPILEPSY & BEHAVIOR

Pharmacokinetic-Pharmacodynamic Modeling of Intravenous and Oral Topiramate and Its Effect on the Symbol-Digit Modalities Test in Adult Healthy Volunteers

(2015) Chay Ngee Lim et al.   JOURNAL OF CLINICAL PHARMACOLOGY

First trimester exposure to topiramate and the risk of oral clefts in the offspring: A systematic review and meta-analysis

(2015) Abdulaziz M.S. Alsaad et al.   REPRODUCTIVE TOXICOLOGY

Topiramate may not increase risk of urolithiasis: A nationwide population-based cohort study

(2015) Ai-Ling Shen et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective

(2015) Alan Talevi   Frontiers in Pharmacology

Increased risk of urinary calculi in patients with migraine: A nationwide cohort study

(2014) Min-Juei Tsai et al.   CEPHALALGIA

Adherence to oral migraine-preventive medications among patients with chronic migraine

(2014) Zsolt Hepp et al.   CEPHALALGIA

Efficacy and mechanism of anticonvulsant drugs in migraine

(2014) Jan Hoffmann et al.   Expert Review of Clinical Pharmacology

Topiramate is likely to act outside of the trigeminocervical complex

(2013) Robin J Storer et al.   CEPHALALGIA

Increased susceptibility to cortical spreading depression in an animal model of medication-overuse headache

(2013) A Laine Green et al.   CEPHALALGIA

Comparative steady-state pharmacokinetic evaluation of immediate-release topiramate and USL255, a once-daily extended-release topiramate formulation

(2013) Meir Bialer et al.   EPILEPSIA

Intravenous topiramate: Safety and pharmacokinetics following a single dose in patients with epilepsy or migraines taking oral topiramate

(2013) Anne M. Clark et al.   EPILEPSIA

Migraine: The Seventh Disabler

(2013) Timothy J. Steiner et al.   HEADACHE

Childhood and Adolescent Migraine Prevention (CHAMP) Study: A Double-Blinded, Placebo-Controlled, Comparative Effectiveness Study of Amitriptyline, Topiramate, and Placebo in the Prevention of Childhood and Adolescent Migraine

(2013) Andrew D. Hershey et al.   HEADACHE

Suppressive effect of chronic peroral topiramate on potassium-induced cortical spreading depression in rats

(2012) Miyuki Unekawa et al.   CEPHALALGIA

The effect of topiramate plasma concentration on linguistic behavior, verbal recall and working memory

(2012) S.E. Marino et al.   EPILEPSY & BEHAVIOR

The Association of Obesity With Episodic and Chronic Migraine

(2012) Randolph W. Evans et al.   HEADACHE

Randomized, placebo-controlled trial of propranolol added to topiramate in chronic migraine

(2012) S. D. Silberstein et al.   NEUROLOGY

Evidence-based guideline update: Pharmacologic treatment for episodic migraine prevention in adults: Table 1

(2012) S.D. Silberstein et al.   NEUROLOGY

Topiramate in the treatment of migraine: A kainate (glutamate) receptor antagonist within the trigeminothalamic pathway

(2011) Anna P Andreou et al.   CEPHALALGIA

Palinopsia in patients with migraine: A case-control study

(2011) Vincenzo Belcastro et al.   CEPHALALGIA

Genetic and environmental correlates of topiramate-induced cognitive impairment

(2011) Elizabeth T. Cirulli et al.   EPILEPSIA

cAMP-Dependent protein kinase A activity modulates topiramate potentiation of GABAA receptors

(2011) Timothy A. Simeone et al.   EPILEPSY RESEARCH

Topiramate intervention to prevent transformation of episodic migraine: The topiramate INTREPID study

(2010) Richard B Lipton et al.   CEPHALALGIA

Pharmacokinetic-pharmacodynamic assessment of topiramate dosing regimens for children with epilepsy 2 to

(2010) Ihab G. Girgis et al.   EPILEPSIA

Topiramate dose effects on cognition: A randomized double-blind study

(2010) D. W. Loring et al.   NEUROLOGY

Patients With and Without Prior Urolithiasis Have Hypocitraturia and Incident Kidney Stones While on Topiramate

(2010) Daniel M. Kaplon et al.   UROLOGY

Intracisternal Injection of Inflammatory Soup Activates the Trigeminal Nerve System

(2009) J Hoffmann et al.   CEPHALALGIA

Weight Change and Clinical Markers of Cardiovascular Disease Risk During Preventive Treatment of Migraine

(2009) ME Bigal et al.   CEPHALALGIA

Utility of Topiramate for the Treatment of Patients with Chronic Migraine in the Presence or Absence of Acute Medication Overuse

(2009) H-C Diener et al.   CEPHALALGIA

Persistence with Migraine Prophylactic Treatment and Acute Migraine Medication Utilization in the Managed Care Setting

(2009) Avin Z. Yaldo et al.   CLINICAL THERAPEUTICS

Topiramate versus amitriptyline in migraine prevention: A 26-week, multicenter, randomized, double-blind, double-dummy, parallel-group noninferiority trial in adult migraineurs

(2009) David W. Dodick et al.   CLINICAL THERAPEUTICS

The Effect of Migraine Prophylaxis on Migraine-Related Resource Use and Productivity

(2009) Miguel J.A. Láinez   CNS DRUGS

Resource utilization impact of topiramate for migraine prevention in the managed-care setting

(2009) Debra A. Wertz et al.   CURRENT MEDICAL RESEARCH AND OPINION

Rejection and Acceptance of Possible Side Effects of Migraine Prophylactic Drugs

(2009) Pedro A. Kowacs et al.   HEADACHE

Funding of Research on Headache Disorders by the National Institutes of Health

(2009) Todd J. Schwedt et al.   HEADACHE

Topiramate Treatment of Chronic Migraine: A Randomized, Placebo-Controlled Trial of Quality of Life and Other Efficacy Measures

(2009) Stephen Silberstein et al.   HEADACHE

Economic Burden of Transformed Migraine: Results From the American Migraine Prevalence and Prevention (AMPP) Study

(2009) Julie Munakata et al.   HEADACHE

Topiramate Reduces Excitability in the Basolateral Amygdala by Selectively Inhibiting GluK1 (GluR5) Kainate Receptors on Interneurons and Positively Modulating GABAA Receptors on Principal Neurons

(2009) M. F. M. Braga et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Topiramate for Migraine Prevention in Pediatric Subjects 12 to 17 Years of Age

(2009) D. Lewis et al.   PEDIATRICS

Mechanically-induced cortical spreading depression associated regional cerebral blood flow changes are blocked by Na+ ion channel blockade

(2008) Simon Akerman et al.   BRAIN RESEARCH

Are Migraineurs at Increased Risk of Adverse Drug Responses?: A Meta-Analytic Comparison of Topiramate-Related Adverse Drug Reactions in Epilepsy and Migraine

(2008) J Luykx et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Molecular Pharmacodynamics, Clinical Therapeutics, and Pharmacokinetics of Topiramate

(2008) Richard P. Shank et al.   CNS Neuroscience & Therapeutics

Release of Glutamate and CGRP from Trigeminal Ganglion Neurons: Role of Calcium Channels and 5-HT1 Receptor Signaling

(2008) Yan Xiao et al.   Molecular Pain

Analysis of Safety and Tolerability Data Obtained from Over 1,500 Patients Receiving Topiramate for Migraine Prevention in Controlled Trials

(2008) James Adelman et al.   PAIN MEDICINE

Induction of Progressive Profound Hypocitraturia with Increasing Doses of Topiramate

(2008) Brad W. Warner et al.   UROLOGY