Diuretics with carbonic anhydrase inhibitory action: a patent and literature review (2005 – 2013)

Restoring catalytic activity to the human carbonic anhydrase (CA) related proteins VIII, X and XI affords isoforms with high catalytic efficiency and susceptibility to anion inhibition

(2012) Isao Nishimori et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

(2012) Hee Lee et al.   BMC Systems Biology

Polypharmacology of sulfonamides: pazopanib, a multitargeted receptor tyrosine kinase inhibitor in clinical use, potently inhibits several mammalian carbonic anhydrases

(2012) Jean-Yves Winum et al.   CHEMICAL COMMUNICATIONS

Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?

(2012) Vincenzo Alterio et al.   CHEMICAL REVIEWS

Update on carbonic anhydrase inhibitors: a patent review (2008 – 2011)

(2012) Mayank Aggarwal et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Secondary and tertiary sulfonamides: a patent review (2008 – 2012)

(2012) Andrea Scozzafava et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Sulfonamides: a patent review (2008 – 2012)

(2012) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Structure-based drug discovery of carbonic anhydrase inhibitors

(2012) Claudiu T. Supuran   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Structural annotation of human carbonic anhydrases

(2012) Mayank Aggarwal et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Characterization of Carbonic Anhydrase IX Interactome Reveals Proteins Assisting Its Nuclear Localization in Hypoxic Cells

(2012) Pasquale Buanne et al.   JOURNAL OF PROTEOME RESEARCH

Renal carbonic anhydrases are involved in the reabsorption of endogenous nitrite

(2012) Kristine Chobanyan-Jürgens et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Novel therapies for glaucoma: a patent review 2007 – 2011

(2011) Fabrizio Carta et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Acetaldehyde-derived modifications on cytosolic human carbonic anhydrases

(2011) Fatemeh Bootorabi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology

(2011) Francesca Fabrizi et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Carbonic anhydrase inhibitors

(2010) Claudiu T. Supuran   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Carbonic Anhydrase Inhibition/Activation: Trip of a Scientist Around the World in the Search of Novel Chemotypes and Drug Targets

(2010) Claudiu T. Supuran   CURRENT PHARMACEUTICAL DESIGN

Carbonic anhydrase inhibition with natural products: novel chemotypes and inhibition mechanisms

(2010) Claudiu T. Supuran   MOLECULAR DIVERSITY

Carbonic Anhydrase Inhibitors. Comparison of Chlorthalidone and Indapamide X-ray Crystal Structures in Adducts with Isozyme II: When Three Water Molecules and the Keto−Enol Tautomerism Make the Difference†

(2009) Claudia Temperini et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Comparison of chlorthalidone, indapamide, trichloromethiazide, and furosemide X-ray crystal structures in adducts with isozyme II, when several water molecules make the difference

(2008) Claudia Temperini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide–isozyme II adduct

(2008) Claudia Temperini et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Diuretics: From Classical Carbonic Anhydrase Inhibitors to Novel Applications of the Sulfonamides

(2008) Claudiu Supuran   CURRENT PHARMACEUTICAL DESIGN

Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

(2008) Claudiu T. Supuran   NATURE REVIEWS DRUG DISCOVERY

Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited—old leads for new applications?

(2008) Claudia Temperini et al.   ORGANIC & BIOMOLECULAR CHEMISTRY