Human Type IV P-type ATPases That Work as Plasma Membrane Phospholipid Flippases and Their Regulation by Caspase and Calcium

Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

(2015) S. Lee et al.   EMBO JOURNAL

Phospholipid Flippase ATP10A Translocates Phosphatidylcholine and Is Involved in Plasma Membrane Dynamics

(2015) Tomoki Naito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of developmental neurite pruning

(2014) Oren Schuldiner et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Exposure of Phosphatidylserine by Xk-related Protein Family Members during Apoptosis

(2014) Jun Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipid Flippase Activities and Substrate Specificities of Human Type IV P-type ATPases Localized to the Plasma Membrane

(2014) Hiroyuki Takatsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray structure of a calcium-activated TMEM16 lipid scramblase

(2014) Janine D. Brunner et al.   NATURE

Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

(2014) K. Segawa et al.   SCIENCE

Auto-inhibition of Drs2p, a Yeast Phospholipid Flippase, by Its Carboxyl-terminal Tail

(2013) Xiaoming Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium-dependent Phospholipid Scramblase Activity of TMEM16 Protein Family Members

(2013) Jun Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P4-ATPases: lipid flippases in cell membranes

(2013) Rosa L. Lopez-Marques et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

(2013) J. Suzuki et al.   SCIENCE

Mammalian P4-ATPases and ABC transporters and their role in phospholipid transport

(2012) Jonathan A. Coleman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site

(2012) K. Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina

(2012) L. Ruggiero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations in a P-Type ATPase Gene Cause Axonal Degeneration

(2012) Xianjun Zhu et al.   PLoS Genetics

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

ATP9B, a P4-ATPase (a Putative Aminophospholipid Translocase), Localizes to thetrans-Golgi Network in a CDC50 Protein-independent Manner

(2011) Hiroyuki Takatsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Role of the β-Subunit CDC50A in the Stable Expression, Assembly, Subcellular Localization, and Lipid Transport Activity of the P4-ATPase ATP8A2

(2011) Jonathan A. Coleman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Platelet membrane phospholipid asymmetry: from the characterization of a scramblase activity to the identification of an essential protein mutated in Scott syndrome

(2011) T. LHERMUSIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes

(2011) Mehmet Yabas et al.   NATURE IMMUNOLOGY

The Distribution and Function of Phosphatidylserine in Cellular Membranes

(2010) Peter A. Leventis et al.   Annual Review of Biophysics

Cascleave: towards more accurate prediction of caspase substrate cleavage sites

(2010) Jiangning Song et al.   BIOINFORMATICS

Autoimmunity and the Clearance of Dead Cells

(2010) Shigekazu Nagata et al.   CELL

Functions of phospholipid flippases

(2010) K. Tanaka et al.   JOURNAL OF BIOCHEMISTRY

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia

(2010) Nancy B Ray et al.   NATURE MEDICINE

Phagocytosis of Retinal Rod and Cone Photoreceptors

(2010) Brian M. Kevany et al.   PHYSIOLOGY

Localization, Purification, and Functional Reconstitution of the P4-ATPase Atp8a2, a Phosphatidylserine Flippase in Photoreceptor Disc Membranes

(2009) Jonathan A. Coleman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering a polarity-sensitive biosensor for time-lapse imaging of apoptotic processes and degeneration

(2009) Yujin E Kim et al.   NATURE METHODS

Distinct Flippases Translocate Glycerophospholipids and Oligosaccharide Diphosphate Dolichols across the Endoplasmic Reticulum†

(2008) Sumana Sanyal et al.   BIOCHEMISTRY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression of Atp8b3 in murine testis and its characterization as a testis specific P-type ATPase

(2008) Eun-Yeung Gong et al.   REPRODUCTION