Mechanisms of developmental neurite pruning

Axon and dendrite pruning in Drosophila

(2014) Fengwei Yu et al.   CURRENT OPINION IN NEUROBIOLOGY

Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms

(2014) A. Erturk et al.   JOURNAL OF NEUROSCIENCE

Epidermal Cells Are the Primary Phagocytes in the Fragmentation and Clearance of Degenerating Dendrites in Drosophila

(2014) Chun Han et al.   NEURON

Astrocytes Play a Key Role in Drosophila Mushroom Body Axon Pruning

(2014) Yaniv Hakim et al.   PLoS One

Rapid in vivo forward genetic approach for identifying axon death genes inDrosophila

(2014) Lukas J. Neukomm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synapse elimination in the developing cerebellum

(2013) Kouichi Hashimoto et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Phagocytic glial cells: sculpting synaptic circuits in the developing nervous system

(2013) Dorothy P. Schafer et al.   CURRENT OPINION IN NEUROBIOLOGY

Neurite pruning and neuronal cell death: spatial regulation of shared destruction programs

(2013) Maya Maor-Nof et al.   CURRENT OPINION IN NEUROBIOLOGY

Astrocytes engage unique molecular programs to engulf pruned neuronal debris from distinct subsets of neurons

(2013) O. E. Tasdemir-Yilmaz et al.   GENES & DEVELOPMENT

Phosphatidylserine recognition and induction of apoptotic cell clearance by Drosophila engulfment receptor Draper

(2013) Tran Thanh Tung et al.   JOURNAL OF BIOCHEMISTRY

Target-Derived Neurotrophins Coordinate Transcription and Transport of Bclw to Prevent Axonal Degeneration

(2013) K. E. Cosker et al.   JOURNAL OF NEUROSCIENCE

Astrocytes mediate synapse elimination through MEGF10 and MERTK pathways

(2013) Won-Suk Chung et al.   NATURE

TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

(2013) Allison R Bialas et al.   NATURE NEUROSCIENCE

Plum, an Immunoglobulin Superfamily Protein, Regulates Axon Pruning by Facilitating TGF-β Signaling

(2013) Xiaomeng M. Yu et al.   NEURON

Regulation of Axon Degeneration after Injury and in Development by the Endogenous Calpain Inhibitor Calpastatin

(2013) Jing Yang et al.   NEURON

Compartmentalized Calcium Transients Trigger Dendrite Pruning in Drosophila Sensory Neurons

(2013) T. Kanamori et al.   SCIENCE

Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning

(2013) Corey L. Cusack et al.   Nature Communications

Axonal Pruning Is Actively Regulated by the Microtubule-Destabilizing Protein Kinesin Superfamily Protein 2A

(2013) Maya Maor-Nof et al.   Cell Reports

XIAP Regulates Caspase Activity in Degenerating Axons

(2013) Nicolas Unsain et al.   Cell Reports

A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning

(2013) Jack Jing Lin Wong et al.   PLOS BIOLOGY

The RacGAP β2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus

(2012) Martin M. Riccomagno et al.   CELL

A Novel Drosophila Model of Nerve Injury Reveals an Essential Role of Nmnat in Maintaining Axonal Integrity

(2012) Yanshan Fang et al.   CURRENT BIOLOGY

Axon Regrowth during Development and Regeneration Following Injury Share Molecular Mechanisms

(2012) Shiri P. Yaniv et al.   CURRENT BIOLOGY

The discontinuous nature of neurofilament transport accommodates both establishment and repair of the axonal neurofilament array

(2012) Thomas B. Shea et al.   Cytoskeleton

Caspase levels and execution efficiencies determine the apoptotic potential of the cell

(2012) Anat Florentin et al.   JOURNAL OF CELL BIOLOGY

Spatially Coordinated Kinase Signaling Regulates Local Axon Degeneration

(2012) M. Chen et al.   JOURNAL OF NEUROSCIENCE

In Vivo Nerve-Macrophage Interactions Following Peripheral Nerve Injury

(2012) A. F. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

A Conditioning Lesion Protects Axons from Degeneration via the Wallenda/DLK MAP Kinase Signaling Cascade

(2012) X. Xiong et al.   JOURNAL OF NEUROSCIENCE

An Interaction Screen Identifies headcase as a Regulator of Large-Scale Pruning

(2012) N. Loncle et al.   JOURNAL OF NEUROSCIENCE

A Caspase Cascade Regulating Developmental Axon Degeneration

(2012) D. J. Simon et al.   JOURNAL OF NEUROSCIENCE

Pervasive Synaptic Branch Removal in the Mammalian Neuromuscular System at Birth

(2012) Juan C. Tapia et al.   NEURON

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

Genetic Dissection of TAM Receptor-Ligand Interaction in Retinal Pigment Epithelial Cell Phagocytosis

(2012) Tal Burstyn-Cohen et al.   NEURON

Drosophila Motor Neuron Retraction during Metamorphosis Is Mediated by Inputs from TGF-β/BMP Signaling and Orphan Nuclear Receptors

(2012) Ana Boulanger et al.   PLoS One

Sexually Dimorphic BDNF Signaling Directs Sensory Innervation of the Mammary Gland

(2012) Y. Liu et al.   SCIENCE

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

(2012) J. M. Osterloh et al.   SCIENCE

p75 neurotrophin receptor signaling in nervous system injury and degeneration: paradox and opportunity

(2012) Carlos F. Ibáñez et al.   TRENDS IN NEUROSCIENCES

The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

(2012) Xin Xiong et al.   PLOS BIOLOGY

Image-based Screening Identifies Novel Roles for IκB Kinase and Glycogen Synthase Kinase 3 in Axonal Degeneration

(2011) Josiah Gerdts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity

(2011) Arundhati Sengupta Ghosh et al.   JOURNAL OF CELL BIOLOGY

Dendrites Have a Rapid Program of Injury-Induced Degeneration That Is Molecularly Distinct from Developmental Pruning

(2011) J. Tao et al.   JOURNAL OF NEUROSCIENCE

ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation

(2011) Shuji Wakatsuki et al.   NATURE CELL BIOLOGY

Glia instruct developmental neuronal remodeling through TGF-β signaling

(2011) Takeshi Awasaki et al.   NATURE NEUROSCIENCE

Enhancer-driven membrane markers for analysis of nonautonomous mechanisms reveal neuron-glia interactions in Drosophila

(2011) C. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning

(2010) S. M. Martin et al.   DEVELOPMENT

Distinct Presynaptic and Postsynaptic Dismantling Processes of Drosophila Neuromuscular Junctions during Metamorphosis

(2010) Z. Liu et al.   JOURNAL OF NEUROSCIENCE

Axonal Degeneration Is Regulated by the Apoptotic Machinery or a NAD+-Sensitive Pathway in Insects and Mammals

(2010) Z. Schoenmann et al.   JOURNAL OF NEUROSCIENCE

ftz-f1 and Hr39 opposing roles on EcR expression during Drosophila mushroom body neuron remodeling

(2010) Ana Boulanger et al.   NATURE NEUROSCIENCE

p75NTR-dependent, myelin-mediated axonal degeneration regulates neural connectivity in the adult brain

(2010) Katya J Park et al.   NATURE NEUROSCIENCE

Branching out: mechanisms of dendritic arborization

(2010) Yuh-Nung Jan et al.   NATURE REVIEWS NEUROSCIENCE

Visual Map Development: Bidirectional Signaling, Bifunctional Guidance Molecules, and Competition

(2010) D. A. Feldheim et al.   Cold Spring Harbor Perspectives in Biology

Can’t live without them, can live with them: roles of caspases during vital cellular processes

(2009) Yael Feinstein-Rotkopf et al.   APOPTOSIS

Ensheathing Glia Function as Phagocytes in the Adult Drosophila Brain

(2009) J. Doherty et al.   JOURNAL OF NEUROSCIENCE

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Ephrin-B3 reverse signaling through Grb4 and cytoskeletal regulators mediates axon pruning

(2009) Nan-Jie Xu et al.   NATURE NEUROSCIENCE

A genetic pathway composed of Sox14 and Mical governs severing of dendrites during pruning

(2009) Daniel Kirilly et al.   NATURE NEUROSCIENCE

Drosophila IKK-related kinase Ik2 and Katanin p60-like 1 regulate dendrite pruning of sensory neuron during metamorphosis

(2009) H.-H. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Remodeling: Refining Neural Connectivity at the Neuromuscular Junction

(2009) Won-Suk Chung et al.   PLOS BIOLOGY

piggyBac-Based Mosaic Screen Identifies a Postmitotic Function for Cohesin in Regulating Developmental Axon Pruning

(2008) Oren Schuldiner et al.   DEVELOPMENTAL CELL

Organization and Postembryonic Development of Glial Cells in the Adult Central Brain of Drosophila

(2008) T. Awasaki et al.   JOURNAL OF NEUROSCIENCE

Lysosomal Activity Associated with Developmental Axon Pruning

(2008) J. W. Song et al.   JOURNAL OF NEUROSCIENCE

Review of the Multiple Aspects of Neurofilament Functions, and their Possible Contribution to Neurodegeneration

(2008) Rodolphe Perrot et al.   MOLECULAR NEUROBIOLOGY

Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration

(2008) Karun K Singh et al.   NATURE NEUROSCIENCE

Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex

(2008) L. K. Low et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA