Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast

Functions of autophagy in normal and diseased liver

(2013) Mark J. Czaja et al.   Autophagy

Promiscuity as a functional trait: intrinsically disordered regions as central players of interactomes

(2013) Alexander Cumberworth et al.   BIOCHEMICAL JOURNAL

SnapShot: Selective Autophagy

(2013) Meiyan Jin et al.   CELL

Resilience of death: intrinsic disorder in proteins involved in the programmed cell death

(2013) Z Peng et al.   CELL DEATH AND DIFFERENTIATION

Conformational Propensities of Intrinsically Disordered Proteins from NMR Chemical Shifts

(2013) Jaka Kragelj et al.   CHEMPHYSCHEM

The most important thing is the tail: Multitudinous functionalities of intrinsically disordered protein termini

(2013) Vladimir N. Uversky   FEBS LETTERS

The Mechanism and Physiological Function of Macroautophagy

(2013) Daniel J. Klionsky et al.   Journal of Innate Immunity

Modulation of allostery by protein intrinsic disorder

(2013) Allan Chris M. Ferreon et al.   NATURE

Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation

(2013) K. Mao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A decade and a half of protein intrinsic disorder: Biology still waits for physics

(2013) Vladimir N. Uversky   PROTEIN SCIENCE

Structural divergence is more extensive than sequence divergence for a family of intrinsically disordered proteins

(2013) Wade Borcherds et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?

(2013) Angélique Deleersnijder et al.   TRENDS IN MOLECULAR MEDICINE

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

Describing sequence–ensemble relationships for intrinsically disordered proteins

(2012) Albert H. Mao et al.   BIOCHEMICAL JOURNAL

The Neuroendocrine Protein 7B2 Is Intrinsically Disordered

(2012) Indrani Dasgupta et al.   BIOCHEMISTRY

Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

(2012) Michael J. Ragusa et al.   CELL

Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7–Atg3 and Atg7–Atg10 structures

(2012) Stephen E Kaiser et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intrinsically disordered proteins: regulation and disease

(2011) M Madan Babu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Atg8 Transfer from Atg7 to Atg3: A Distinctive E1-E2 Architecture and Mechanism in the Autophagy Pathway

(2011) Asad M. Taherbhoy et al.   MOLECULAR CELL

Structural Basis of Atg8 Activation by a Homodimeric E1, Atg7

(2011) Nobuo N. Noda et al.   MOLECULAR CELL

Insights into noncanonical E1 enzyme activation from the structure of autophagic E1 Atg7 with Atg8

(2011) Seung Beom Hong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Solution structure of Atg8 reveals conformational polymorphism of the N-terminal domain

(2010) Melanie Schwarten et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PONDR-FIT: A meta-predictor of intrinsically disordered amino acids

(2010) Bin Xue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Understanding protein non-folding

(2010) Vladimir N. Uversky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes

(2010) Vladimir N. Uversky   CHEMICAL SOCIETY REVIEWS

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

The amino-terminal region of Atg3 is essential for association with phosphatidylethanolamine in Atg8 lipidation

(2009) Takao Hanada et al.   FEBS LETTERS

CDF it all: Consensus prediction of intrinsically disordered proteins based on various cumulative distribution functions

(2009) Bin Xue et al.   FEBS LETTERS

Dimeric Coiled-coil Structure ofSaccharomyces cerevisiaeAtg16 and Its Functional Significance in Autophagy

(2009) Yuko Fujioka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intrinsically Disordered Proteins and Their Environment: Effects of Strong Denaturants, Temperature, pH, Counter Ions, Membranes, Binding Partners, Osmolytes, and Macromolecular Crowding

(2009) Vladimir N. Uversky   PROTEIN JOURNAL

Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept

(2008) Vladimir N. Uversky et al.   Annual Review of Biophysics

Intrinsic disorder in pathogenic and non-pathogenic microbes: discovering and analyzing the unfoldomes of early-branching eukaryotes

(2008) Amrita Mohan et al.   Molecular BioSystems

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS