Conformational Propensities of Intrinsically Disordered Proteins from NMR Chemical Shifts

Comparative Studies of Disordered Proteins with Similar Sequences: Application to Aβ40 and Aβ42

(2013) Charles K. Fisher et al.   BIOPHYSICAL JOURNAL

Chemical shifts in biomolecules

(2013) David A Case   CURRENT OPINION IN STRUCTURAL BIOLOGY

Describing intrinsically disordered proteins at atomic resolution by NMR

(2013) Malene Ringkjøbing Jensen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Improving the chemical shift dispersion of multidimensional NMR spectra of intrinsically disordered proteins

(2013) Wolfgang Bermel et al.   JOURNAL OF BIOMOLECULAR NMR

Chemical shift prediction for denatured proteins

(2013) James H. Prestegard et al.   JOURNAL OF BIOMOLECULAR NMR

BEST-TROSY experiments for time-efficient sequential resonance assignment of large disordered proteins

(2013) Zsofia Solyom et al.   JOURNAL OF BIOMOLECULAR NMR

Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’

(2013) Joseph M. Rogers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Dynamic Structure of α-Synuclein Multimers

(2013) Thomas Gurry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Prediction of NMR Residual Dipolar Couplings from the Primary Sequence of Unfolded Proteins

(2012) Jie-rong Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Describing sequence–ensemble relationships for intrinsically disordered proteins

(2012) Albert H. Mao et al.   BIOCHEMICAL JOURNAL

Residual dipolar couplings measured in unfolded proteins are sensitive to amino-acid-specific geometries as well as local conformational sampling

(2012) Jie-rong Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Using NMR chemical shifts to calculate the propensity for structural order and disorder in proteins

(2012) Kamil Tamiola et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Bacterial in-cell NMR of human α-synuclein: a disordered monomer by nature?: Figure 1

(2012) Andres Binolfi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Disentangling the Coil: Modulation of Conformational and Dynamic Properties by Site-Directed Mutation in the Non-Native State of Hen Egg White Lysozyme

(2012) Friederike Sziegat et al.   BIOCHEMISTRY

Determination of Secondary Structure Populations in Disordered States of Proteins Using Nuclear Magnetic Resonance Chemical Shifts

(2012) Carlo Camilloni et al.   BIOCHEMISTRY

Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties

(2012) Alexander S. Maltsev et al.   BIOCHEMISTRY

Unusual biophysics of intrinsically disordered proteins

(2012) Vladimir N. Uversky   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Characterization of disordered proteins with ENSEMBLE

(2012) Mickaël Krzeminski et al.   BIOINFORMATICS

Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables

(2012) V. Ozenne et al.   BIOINFORMATICS

MetaDisorder: a meta-server for the prediction of intrinsic disorder in proteins

(2012) Lukasz P Kozlowski et al.   BMC BIOINFORMATICS

Intrinsically Disordered Proteins: From Sequence and Conformational Properties toward Drug Discovery

(2012) Nasrollah Rezaei-Ghaleh et al.   CHEMBIOCHEM

Probing the diverse landscape of protein flexibility and binding

(2012) Joseph A Marsh et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, andEscherichia coliExists Predominantly as Disordered Monomer

(2012) Bruno Fauvet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

4D Non-uniformly sampled HCBCACON and 1 J(NCα)-selective HCBCANCO experiments for the sequential assignment and chemical shift analysis of intrinsically disordered proteins

(2012) Jiří Nováček et al.   JOURNAL OF BIOMOLECULAR NMR

PPM: a side-chain and backbone chemical shift predictor for the assessment of protein conformational ensembles

(2012) Da-Wei Li et al.   JOURNAL OF BIOMOLECULAR NMR

High dimensional and high resolution pulse sequences for backbone resonance assignment of intrinsically disordered proteins

(2012) Anna Zawadzka-Kazimierczuk et al.   JOURNAL OF BIOMOLECULAR NMR

Speeding up sequence specific assignment of IDPs

(2012) Wolfgang Bermel et al.   JOURNAL OF BIOMOLECULAR NMR

Mapping the Potential Energy Landscape of Intrinsically Disordered Proteins at Amino Acid Resolution

(2012) Valéry Ozenne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequence-Specific Mapping of the Interaction between Urea and Unfolded Ubiquitin from Ensemble Analysis of NMR and Small Angle Scattering Data

(2012) Jie-rong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interpreting Protein Structural Dynamics from NMR Chemical Shifts

(2012) Paul Robustelli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intrinsically disordered proteins: a 10-year recap

(2012) Peter Tompa   TRENDS IN BIOCHEMICAL SCIENCES

Constructing ensembles for intrinsically disordered proteins

(2011) Charles K Fisher et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Unstructural biology coming of age

(2011) Peter Tompa   CURRENT OPINION IN STRUCTURAL BIOLOGY

Intrinsically disordered proteins: regulation and disease

(2011) M Madan Babu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

5D 13C-detected experiments for backbone assignment of unstructured proteins with a very low signal dispersion

(2011) Jiří Nováček et al.   JOURNAL OF BIOMOLECULAR NMR

Extension of the HA-detection based approach: (HCA)CON(CA)H and (HCA)NCO(CA)H experiments for the main-chain assignment of intrinsically disordered proteins

(2011) Sampo Mäntylahti et al.   JOURNAL OF BIOMOLECULAR NMR

Sequence correction of random coil chemical shifts: correlation between neighbor correction factors and changes in the Ramachandran distribution

(2011) Magnus Kjaergaard et al.   JOURNAL OF BIOMOLECULAR NMR

Random coil chemical shift for intrinsically disordered proteins: effects of temperature and pH

(2011) Magnus Kjaergaard et al.   JOURNAL OF BIOMOLECULAR NMR

SHIFTX2: significantly improved protein chemical shift prediction

(2011) Beomsoo Han et al.   JOURNAL OF BIOMOLECULAR NMR

Sparsely sampled high-resolution 4-D experiments for efficient backbone resonance assignment of disordered proteins

(2011) Jie Wen et al.   JOURNAL OF MAGNETIC RESONANCE

Explaining the Structural Plasticity of α-Synuclein

(2011) Orly Ullman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Impact of Proline-Directed Pseudophosphorylation at AT8, AT100, and PHF1 Epitopes on 441-Residue Tau

(2011) Stefan Bibow et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards a robust description of intrinsic protein disorder using nuclear magnetic resonance spectroscopy

(2011) Robert Schneider et al.   Molecular BioSystems

Fuzziness: linking regulation to protein dynamics

(2011) Monika Fuxreiter   Molecular BioSystems

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

(2011) Tim Bartels et al.   NATURE

Intrinsic disorder in measles virus nucleocapsids

(2011) M. R. Jensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A soluble  -synuclein construct forms a dynamic tetramer

(2011) W. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disordered proteins studied by chemical shifts

(2011) Magnus Kjaergaard et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Ensemble modeling of protein disordered states: Experimental restraint contributions and validation

(2011) Joseph A. Marsh et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Expanding the proteome: disordered and alternatively folded proteins

(2011) H. Jane Dyson   QUARTERLY REVIEWS OF BIOPHYSICS

Multitude of binding modes attainable by intrinsically disordered proteins: a portrait gallery of disorder-based complexes

(2010) Vladimir N. Uversky   CHEMICAL SOCIETY REVIEWS

HA-detected experiments for the backbone assignment of intrinsically disordered proteins

(2010) Sampo Mäntylahti et al.   JOURNAL OF BIOMOLECULAR NMR

SPARTA+: a modest improvement in empirical NMR chemical shift prediction by means of an artificial neural network

(2010) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein

(2010) Stéphane Gely et al.   JOURNAL OF MOLECULAR RECOGNITION

Enhanced Conformational Space Sampling Improves the Prediction of Chemical Shifts in Proteins

(2010) Phineus R. L. Markwick et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Defining Conformational Ensembles of Intrinsically Disordered and Partially Folded Proteins Directly from Chemical Shifts

(2010) Malene Ringkjøbing Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Automatic Assignment of the Intrinsically Disordered Protein Tau with 441-Residues

(2010) Rhagavendran L. Narayanan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequence-Specific Random Coil Chemical Shifts of Intrinsically Disordered Proteins

(2010) Kamil Tamiola et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modeling Intrinsically Disordered Proteins with Bayesian Statistics

(2010) Charles K. Fisher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NMR Characterization of Long-Range Order in Intrinsically Disordered Proteins

(2010) Loïc Salmon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Signature of the MYPT1−PP1 Interaction

(2010) Anderson S. Pinheiro et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folding and binding cascades: Dynamic landscapes and population shifts

(2010) Sandeep Kumar et al.   PROTEIN SCIENCE

Structural Diversity in Free and Bound States of Intrinsically Disordered Protein Phosphatase 1 Regulators

(2010) Joseph A. Marsh et al.   STRUCTURE

Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 with the Cdc4 Subunit of an SCF Ubiquitin Ligase

(2010) Tanja Mittag et al.   STRUCTURE

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

(2009) Vladimir N Uversky et al.   BMC GENOMICS

NMR chemical shift data and ab initio shielding calculations: emerging tools for protein structure determination

(2009) Frans A. A. Mulder et al.   CHEMICAL SOCIETY REVIEWS

Biophysical characterization of intrinsically disordered proteins

(2009) David Eliezer   CURRENT OPINION IN STRUCTURAL BIOLOGY

H-start for exclusively heteronuclear NMR spectroscopy: The case of intrinsically disordered proteins

(2009) Wolfgang Bermel et al.   JOURNAL OF MAGNETIC RESONANCE

Structure and Disorder in an Unfolded State under Nondenaturing Conditions from Ensemble Models Consistent with a Large Number of Experimental Restraints

(2009) Joseph A. Marsh et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Characterization of the Natively Unfolded N-Terminal Domain of Human c-Src Kinase: Insights into the Role of Phosphorylation of the Unique Domain

(2009) Yolanda Pérez et al.   JOURNAL OF MOLECULAR BIOLOGY

Certification of Molecular Dynamics Trajectories with NMR Chemical Shifts

(2009) Da-Wei Li et al.   Journal of Physical Chemistry Letters

Circular Dichroism Spectrum of Peptides in the Poly(Pro)II Conformation

(2009) Robert W. Woody   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Description of Backbone Conformational Sampling of Unfolded Proteins at Amino Acid Resolution from NMR Residual Dipolar Couplings

(2009) Gabrielle Nodet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fast and Accurate Predictions of Protein NMR Chemical Shifts from Interatomic Distances

(2009) Kai J. Kohlhoff et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Modelfree Analysis of Urea Binding to Unfolded Ubiquitin Using a Combination of Small Angle X-ray and Neutron Scattering

(2009) Frank Gabel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Accurate Random Coil Chemical Shifts from an Analysis of Loop Regions in Native States of Proteins

(2009) Alfonso De Simone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural characterization of α-synuclein in an aggregation prone state

(2009) Min-Kyu Cho et al.   PROTEIN SCIENCE

Quantitative Determination of the Conformational Properties of Partially Folded and Intrinsically Disordered Proteins Using NMR Dipolar Couplings

(2009) Malene Ringkjøbing Jensen et al.   STRUCTURE

The unfoldomics decade: an update on intrinsically disordered proteins

(2008) A Keith Dunker et al.   BMC GENOMICS

Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners

(2008) Christopher J Oldfield et al.   BMC GENOMICS

MeDor: a metaserver for predicting protein disorder

(2008) Philippe Lieutaud et al.   BMC GENOMICS

Function and structure of inherently disordered proteins

(2008) A Keith Dunker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Model-independent interpretation of NMR relaxation data for unfolded proteins: the acid-denatured state of ACBP

(2008) Kristofer Modig et al.   JOURNAL OF BIOMOLECULAR NMR

Conformational distributions of unfolded polypeptides from novel NMR techniques

(2008) Sebastian Meier et al.   JOURNAL OF CHEMICAL PHYSICS

On the Origin of NMR Dipolar Waves in Transient Helical Elements of Partially Folded Proteins

(2008) Malene Ringkjøbing Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural and Dynamic Characterization of Intrinsically Disordered Human Securin by NMR Spectroscopy

(2008) Veronika Csizmok et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Conformational Analysis of Partially Folded Proteins from Residual Dipolar Couplings: Application to the Molecular Recognition Element of Sendai Virus Nucleoprotein

(2008) Malene Ringkjøbing Jensen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Consistent blind protein structure generation from NMR chemical shift data

(2008) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

(2007) Peter Tompa et al.   TRENDS IN BIOCHEMICAL SCIENCES