标题
Therapeutic targets for rheumatoid arthritis: Progress and promises
作者
关键词
-
出版物
AUTOIMMUNITY
Volume 47, Issue 2, Pages 77-94
出版商
Informa UK Limited
发表日期
2014-01-20
DOI
10.3109/08916934.2013.873413
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- IL-17/Th17 mediated synovial inflammation is IL-22 independent
- (2013) Jan Piet van Hamburg et al. ANNALS OF THE RHEUMATIC DISEASES
- TNF Inhibition for Ophthalmic Indications: Current Status and Outlook
- (2013) Lana M. Rifkin et al. BIODRUGS
- Human CD4+ effector T lymphocytes generated upon TCR engagement with self-peptides respond defectively to IL-7 in their transition to memory cells
- (2013) Gabriela González-Pérez et al. Cellular & Molecular Immunology
- Kinase inhibitors: A new tool for the treatment of rheumatoid arthritis
- (2013) Soumya D. Chakravarty et al. CLINICAL IMMUNOLOGY
- IL-32 with potential insights into rheumatoid arthritis
- (2013) Wang-Dong Xu et al. CLINICAL IMMUNOLOGY
- Mitogen-Activated Protein Kinases as Therapeutic Targets for Rheumatoid Arthritis
- (2013) Verica Paunovic et al. DRUGS
- A biological therapy to osteoarthritis treatment using platelet-rich plasma
- (2013) Eduardo Anitua et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Interleukin-18 gene polymorphisms and rheumatoid arthritis: A meta-analysis
- (2013) Jong Dae Ji et al. GENE
- Specific siRNA Targeting Receptor for Advanced Glycation End Products (RAGE) Decreases Proliferation in Human Breast Cancer Cell Lines
- (2013) AL-Madhagi Radia et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Novel Role of IL-7 Ligation to IL-7 Receptor in Myeloid Cells of Rheumatoid Arthritis and Collagen-Induced Arthritis
- (2013) Z. Chen et al. JOURNAL OF IMMUNOLOGY
- Biologic agents in osteoarthritis: hopes and disappointments
- (2013) Xavier Chevalier et al. Nature Reviews Rheumatology
- The problem of choice: current biologic agents and future prospects in RA
- (2013) Ernest H. Choy et al. Nature Reviews Rheumatology
- Visfatin and adiponectin as novel markers for evaluation of metabolic disturbance in recently diagnosed rheumatoid arthritis patients
- (2013) Sahar Hossam El-Hini et al. RHEUMATOLOGY INTERNATIONAL
- Resistin in inflammatory and degenerative rheumatologic diseases
- (2013) S.M.H. Fadda et al. ZEITSCHRIFT FUR RHEUMATOLOGIE
- Progression to rheumatoid arthritis in early inflammatory arthritis is associated with low IL-7 serum levels
- (2012) Vincent Goëb et al. ANNALS OF THE RHEUMATIC DISEASES
- Adiponectin isoforms: a potential therapeutic target in rheumatoid arthritis?
- (2012) Klaus W Frommer et al. ANNALS OF THE RHEUMATIC DISEASES
- Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis
- (2012) Qi-Quan Huang et al. ARTHRITIS AND RHEUMATISM
- Regulation of inflammatory responses in tumor necrosis factor-activated and rheumatoid arthritis synovial macrophages by JAK inhibitors
- (2012) Anna Yarilina et al. ARTHRITIS AND RHEUMATISM
- B effector cells in rheumatoid arthritis and experimental arthritis
- (2012) Alison Finnegan et al. AUTOIMMUNITY
- B cells as effectors and regulators of autoimmunity
- (2012) Eliana Mariño et al. AUTOIMMUNITY
- Natural autoantibodies and associated B cells in immunity and autoimmunity
- (2012) Kaiissar Mannoor et al. AUTOIMMUNITY
- S100P-Derived RAGE Antagonistic Peptide Reduces Tumor Growth and Metastasis
- (2012) T. Arumugam et al. CLINICAL CANCER RESEARCH
- Interleukin-7: a key Mediator in T Cell-driven Autoimmunity, Inflammation, and Tissue Destruction
- (2012) Angela Bikker et al. CURRENT PHARMACEUTICAL DESIGN
- Interleukin-32: A predominantly intracellular proinflammatory mediator that controls cell activation and cell death
- (2012) Bas Heinhuis et al. CYTOKINE
- Adiponectin: A biomarker for rheumatoid arthritis?
- (2012) Xiuping Chen et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Emerging role of interleukin-22 in autoimmune diseases
- (2012) Hai-Feng Pan et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Are biological targets the final goal for rheumatoid arthritis therapy?
- (2012) Puja Sharma et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Interleukin 22, a Potential Therapeutic Target for Rheumatoid Arthritis
- (2012) Q. XIE et al. JOURNAL OF RHEUMATOLOGY
- Increased Serum Interleukin 22 in Patients with Rheumatoid Arthritis and Correlation with Disease Activity
- (2012) LAURINDO FERREIRA da ROCHA et al. JOURNAL OF RHEUMATOLOGY
- Increased Frequencies of Th22 Cells as well as Th17 Cells in the Peripheral Blood of Patients with Ankylosing Spondylitis and Rheumatoid Arthritis
- (2012) Lei Zhang et al. PLoS One
- Adiponectin and Leptin Induce VCAM-1 Expression in Human and Murine Chondrocytes
- (2012) Javier Conde et al. PLoS One
- Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines
- (2012) N. J. Logsdon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The efficacy of biologic agents in patients with rheumatoid arthritis and an inadequate response to tumour necrosis factor inhibitors: a systematic review
- (2012) R. J. Moots et al. RHEUMATOLOGY
- Immunity 12 years after alemtuzumab in RA: CD5+ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses
- (2012) A. E. Anderson et al. RHEUMATOLOGY
- Optimizing outcomes in patients with rheumatoid arthritis and an inadequate response to anti-TNF treatment
- (2012) P. Emery RHEUMATOLOGY
- IL-32 aggravates synovial inflammation and bone destruction and increases synovial natural killer cells in experimental arthritis models
- (2012) Young-Eun Park et al. RHEUMATOLOGY INTERNATIONAL
- Interleukin-32-induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase-1 in vitro
- (2012) Hyun-Ja Jeong et al. ARTHRITIS RESEARCH & THERAPY
- Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis
- (2012) Lieying Fan et al. ARTHRITIS RESEARCH & THERAPY
- A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation.
- (2012) Asako Chiba et al. ARTHRITIS RESEARCH & THERAPY
- Functional role of IL-22 in psoriatic arthritis
- (2012) Anupam Mitra et al. ARTHRITIS RESEARCH & THERAPY
- IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis
- (2012) Young-Mee Moon et al. ARTHRITIS RESEARCH & THERAPY
- Kinase inhibitors: a new class of antirheumatic drugs
- (2012) Vasileios Kyttaris Drug Design Development and Therapy
- Interleukin-7 levels in synovial fluid increase with age and MMP-1 levels decrease with progression of osteoarthritis
- (2011) René Rübenhagen et al. Acta Orthopaedica
- Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis
- (2011) J. Leipe et al. ANNALS OF THE RHEUMATIC DISEASES
- Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases
- (2011) Wang Hui et al. ANNALS OF THE RHEUMATIC DISEASES
- Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease
- (2011) Wenjun Ouyang et al. Annual Review of Immunology
- Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation
- (2011) Renoud J. Marijnissen et al. ARTHRITIS AND RHEUMATISM
- The anti-CD20 antibody rituximab reduces the Th17 cell response
- (2011) Frank L. van de Veerdonk et al. ARTHRITIS AND RHEUMATISM
- Interleukin-22 promotes osteoclastogenesis in rheumatoid arthritis through induction of RANKL in human synovial fibroblasts
- (2011) Kyoung-Woon Kim et al. ARTHRITIS AND RHEUMATISM
- Effects of adalimumab therapy on disease activity and interferon-γ-mediated biochemical pathways in patients with rheumatoid arthritis
- (2011) Katharina Kurz et al. AUTOIMMUNITY
- Efficacy and safety of the human anti-IL-1beta monoclonal antibody canakinumab in rheumatoid arthritis: results of a 12-week, phase II, dose-finding study
- (2011) Rieke Alten et al. BMC MUSCULOSKELETAL DISORDERS
- IL-19 as a Potential Therapeutic in Autoimmune and Inflammatory Diseases
- (2011) Yasu-Taka Azuma et al. CURRENT PHARMACEUTICAL DESIGN
- Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis
- (2011) Dass S. Vinay et al. CYTOKINE
- Celecoxib
- (2011) Paul L. McCormack DRUGS
- Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis
- (2011) Lei Zhang et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Interleukin-18: A Mediator of Inflammation and Angiogenesis in Rheumatoid Arthritis
- (2011) Michael V. Volin et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (Pamapimod) and 6-(2,4-Difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as Orally Bioavailable and Highly Selective Inhibitors of p38α Mitogen-Activated Protein Kinase
- (2011) David M. Goldstein et al. JOURNAL OF MEDICINAL CHEMISTRY
- What's new in our understanding of the role of adipokines in rheumatic diseases?
- (2011) Rodolfo Gómez et al. Nature Reviews Rheumatology
- Toward understanding the role of leptin and leptin receptor antagonism in preclinical models of rheumatoid arthritis
- (2011) Laszlo Otvos et al. PEPTIDES
- Interleukin-19 blockade attenuates collagen-induced arthritis in rats
- (2011) Y.-H. Hsu et al. RHEUMATOLOGY
- Negative regulation of NF-κB and its involvement in rheumatoid arthritis
- (2011) Geert van Loo et al. ARTHRITIS RESEARCH & THERAPY
- Serum Adiponectin and Vaspin Levels in Rheumatoid Arthritis
- (2010) Metin Ozgen et al. ARCHIVES OF MEDICAL RESEARCH
- Ofatumumab, a human anti-CD20 monoclonal antibody, for treatment of rheumatoid arthritis with an inadequate response to one or more disease-modifying antirheumatic drugs: Results of a randomized, double-blind, placebo-controlled, phase I/II study
- (2010) Mikkel Østergaard et al. ARTHRITIS AND RHEUMATISM
- Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators
- (2010) Sarita A. Y. Hartgring et al. ARTHRITIS AND RHEUMATISM
- Rheumatoid arthritis therapy: Advances from bench to bedside
- (2010) Soo-In Choi et al. AUTOIMMUNITY
- Regulatory immune cell subsets in autoimmunity
- (2010) Antonio La Cava AUTOIMMUNITY
- Anti-IL-17A therapy protects against bone erosion in experimental models of rheumatoid arthritis
- (2010) Cheng-Chi Chao et al. AUTOIMMUNITY
- KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase
- (2010) Antonio Garrido Montalban et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases
- (2010) Rui-Xue Leng et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Isolation and characterization of human interleukin-10–secreting T cells from peripheral blood
- (2010) Graziella Mazza et al. HUMAN IMMUNOLOGY
- A Multitude of Kinases—Which are the Best Targets in Treating Rheumatoid Arthritis?
- (2010) Tamsin M. Lindstrom et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
- Synovial/Serum leptin ratio in rheumatoid arthritis: the association with activity and erosion
- (2010) Shereen M. Olama et al. RHEUMATOLOGY INTERNATIONAL
- Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis
- (2010) W. Hueber et al. Science Translational Medicine
- Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies
- (2009) Nemanja Damjanov et al. ARTHRITIS AND RHEUMATISM
- Serum adipokine levels in patients with systemic lupus erythematosus
- (2009) Juan B. De Sanctis et al. AUTOIMMUNITY
- AGE and their receptor RAGE in systemic autoimmune diseases: An inflammation propagating factor contributing to accelerated atherosclerosis
- (2009) Hans L. A. Nienhuis et al. AUTOIMMUNITY
- Prospective new biological therapies for rheumatoid arthritis
- (2009) Ladislav Šenolt et al. AUTOIMMUNITY REVIEWS
- The receptor RAGE: Bridging inflammation and cancer
- (2009) Astrid Riehl et al. Cell Communication and Signaling
- Soluble Forms of RAGE in Human Diseases: Clinical and Therapeutical Implications
- (2009) Francesca Santilli et al. CURRENT MEDICINAL CHEMISTRY
- ERK-Dependent T Cell Receptor Threshold Calibration in Rheumatoid Arthritis
- (2009) K. Singh et al. JOURNAL OF IMMUNOLOGY
- Periodic, Partial Inhibition of I B Kinase -Mediated Signaling Yields Therapeutic Benefit in Preclinical Models of Rheumatoid Arthritis
- (2009) K. M. Gillooly et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A Novel, Highly Selective, Tight Binding I B Kinase-2 (IKK-2) Inhibitor: A Tool to Correlate IKK-2 Activity to the Fate and Functions of the Components of the Nuclear Factor- B Pathway in Arthritis-Relevant Cells and Animal Models
- (2009) G. Mbalaviele et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Adiponectin and leptin serum concentrations in patients with rheumatoid arthritis
- (2009) Bożena Targońska-Stępniak et al. RHEUMATOLOGY INTERNATIONAL
- Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocytes
- (2009) Zafar Rasheed et al. ARTHRITIS RESEARCH & THERAPY
- Reduction of serum interleukin 7 levels upon methotrexate therapy in early rheumatoid arthritis correlates with disease suppression
- (2008) J A G van Roon et al. ANNALS OF THE RHEUMATIC DISEASES
- Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study
- (2008) Mark C. Genovese et al. ARTHRITIS AND RHEUMATISM
- Role of the NF-κB axis in immune modulation of osteoclasts and bone loss
- (2008) Yousef Abu-Amer et al. AUTOIMMUNITY
- Review: Immune cells and mediators of inflammatory arthritis
- (2008) Georg Schett AUTOIMMUNITY
- LILRA5 is expressed by synovial tissue macrophages in rheumatoid arthritis, selectively induces pro-inflammatory cytokines and IL-10 and is regulated by TNF-α, IL-10 and IFN-γ
- (2008) Ainslie Mitchell et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Interleukin-7 in rheumatoid arthritis
- (2008) S. M. Churchman et al. RHEUMATOLOGY
- Expression of IL-19 and its receptors in RA: potential role for synovial hyperplasia formation
- (2008) N. Sakurai et al. RHEUMATOLOGY
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started