Oxidative Stress and Lectin-Like Ox-LDL-Receptor LOX-1 in Atherogenesis and Tumorigenesis

The Effects of Vitamin Supplementation on Drosophila Life Span Under Normoxia and Under Oxidative Stress

(2011) S. Bahadorani et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process

(2010) Willem A. den Hengst et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Effect of alpha-tocopherol and beta-carotene supplementation on macrovascular complications and total mortality from diabetes: Results of the ATBC Study

(2010) Merja K. Kataja-Tuomola et al.   ANNALS OF MEDICINE

Macrophage Migration Inhibitory Factor Provides Cardioprotection During Ischemia/Reperfusion by Reducing Oxidative Stress

(2010) Kiyokazu Koga et al.   ANTIOXIDANTS & REDOX SIGNALING

Oxidized Low-Density Lipoprotein-Activated c-Jun NH2-Terminal Kinase Regulates Manganese Superoxide Dismutase Ubiquitination

(2010) Wakako Takabe et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effect of endothelial cell proliferation on atherogenesis: A role of p21Sdi/Cip/Waf1 in monocyte adhesion to endothelial cells

(2010) Hiyo Obikane et al.   ATHEROSCLEROSIS

OxLDL-IgG immune complexes induce expression and secretion of proatherogenic cytokines by cultured human mast cells

(2010) Jani Lappalainen et al.   ATHEROSCLEROSIS

Lectin-like oxidized low-density lipoprotein receptor-1 is required for the adipose tissue expression of proinflammatory cytokines in high-fat diet-induced obese mice

(2010) Rieko Takanabe-Mori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

NADPH oxidase 4 is an oncoprotein localized to mitochondria

(2010) Kelly A. Graham et al.   CANCER BIOLOGY & THERAPY

A Transcriptional Signature and Common Gene Networks Link Cancer with Lipid Metabolism and Diverse Human Diseases

(2010) Heather A. Hirsch et al.   CANCER CELL

Role of NADPH Oxidase in Endothelial Ischemia/Reperfusion Injury in Humans

(2010) Stavros P. Loukogeorgakis et al.   CIRCULATION

Intramyocardial Fibroblast Myocyte Communication

(2010) Rahul Kakkar et al.   CIRCULATION RESEARCH

Nox4 is a Novel Inducible Source of Reactive Oxygen Species in Monocytes and Macrophages and Mediates Oxidized Low Density Lipoprotein–Induced Macrophage Death

(2010) Chi Fung Lee et al.   CIRCULATION RESEARCH

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Molecular Imaging of Atherosclerotic Plaques Targeted to Oxidized LDL Receptor LOX-1 by SPECT/CT and Magnetic Resonance

(2010) Dayuan Li et al.   Circulation-Cardiovascular Imaging

Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis

(2010) Rosa Puca et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Heat shock proteins in ovarian cancer: A potential target for therapy

(2010) Marie Cohen et al.   GYNECOLOGIC ONCOLOGY

Heparin Cofactor II Protects Against Angiotensin II-Induced Cardiac Remodeling Via Attenuation of Oxidative Stress in Mice

(2010) Yuka Sumitomo-Ueda et al.   HYPERTENSION

Reactive oxygen species and vascular biology: implications in human hypertension

(2010) Rhian M Touyz et al.   HYPERTENSION RESEARCH

Tumor Necrosis Factor Receptor-associated Factor-6 and Ribosomal S6 Kinase Intracellular Pathways Link the Angiotensin II AT1 Receptor to the Phosphorylation and Activation of the IκB Kinase Complex in Vascular Smooth Muscle Cells

(2010) Priscilla Doyon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble lectin-like oxidized LDL receptor-1 (sLOX-1) as a sensitive and specific biomarker for acute coronary syndrome—Comparison with other biomarkers

(2010) Noriaki Kume et al.   Journal of Cardiology

Regression and shift in composition of coronary atherosclerotic plaques by pioglitazone: insight from an intravascular ultrasound analysis

(2010) Fabrizio Clementi et al.   Journal of Cardiovascular Medicine

Curcumin Reduces Angiotensin II–mediated Cardiomyocyte Growth via LOX-1 Inhibition

(2010) Bum-Yong Kang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Circulating endothelial progenitor cells, microparticles and vascular disease

(2010) Jawahar L Mehta et al.   JOURNAL OF HYPERTENSION

Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Delivers Heat Shock Protein 60-Fused Antigen into the MHC Class I Presentation Pathway

(2010) J. Xie et al.   JOURNAL OF IMMUNOLOGY

Prognostic Significance of Myocardial Fibrosis in Hypertrophic Cardiomyopathy

(2010) Rory O'Hanlon et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells

(2010) Wen-Jane Lee et al.   JOURNAL OF VASCULAR SURGERY

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

Genomics of cardiac remodeling in angiotensin II-treated wild-type and LOX-1-deficient mice

(2010) Bum-Yong Kang et al.   PHYSIOLOGICAL GENOMICS

Inhibitor of growth-4 promotes I B promoter activation to suppress NF- B signaling and innate immunity

(2010) A. H. Coles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Angiotensin-converting enzyme 2 attenuates atherosclerotic lesions by targeting vascular cells

(2010) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Significance of heterogenity in endothel-dependent vasodilatation occurrence in healthy individuals with or without coronary risk factors

(2010) Marija Polovina et al.   Vojnosanitetski Pregled

Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-α in cerebral vascular endothelial cells

(2009) Shyamali Basuroy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

CRP is a novel ligand for the oxidized LDL receptor LOX-1

(2009) Heather H. Shih et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hydrogen Peroxide as a Cell-Survival Signaling Molecule

(2009) Gillian Groeger et al.   ANTIOXIDANTS & REDOX SIGNALING

JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells

(2009) Adrian Manea et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

LOX-1 dependent overexpression of immunoglobulins in cardiomyocytes in response to angiotensin II

(2009) Bum-Yong Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular mechanisms controlling E-cadherin expression in breast cancer

(2009) Somesh Baranwal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LOX-1 as a natural IFN- -mediated signal for apoptotic cell uptake and antigen presentation in dendritic cells

(2009) S. Parlato et al.   BLOOD

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

(2009) H. A. Hirsch et al.   CANCER RESEARCH

Roles of Nox1 and other Nox isoforms in cancer development

(2009) Tohru Kamata   CANCER SCIENCE

Oxidized low-density lipoproteins upregulate proline oxidase to initiate ROS-dependent autophagy

(2009) O. Zabirnyk et al.   CARCINOGENESIS

Cardiac protection takes off

(2009) H. M. Piper et al.   CARDIOVASCULAR RESEARCH

LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells

(2009) Koichi Sugimoto et al.   CARDIOVASCULAR RESEARCH

Molecular Regulation of Tumor Angiogenesis and Perfusion via Redox Signaling

(2009) Thomas W. Miller et al.   CHEMICAL REVIEWS

Response Gene to Complement 32, a Novel Hypoxia-Regulated Angiogenic Inhibitor

(2009) Xiaojin An et al.   CIRCULATION

LOX-1

(2009) Sayoko Ogura et al.   CIRCULATION JOURNAL

Mediation of Electronegative Low-Density Lipoprotein Signaling by LOX-1

(2009) Jonathan Lu et al.   CIRCULATION RESEARCH

Angiotensin II–Inducible Smooth Muscle Cell Apoptosis Involves the Angiotensin II Type 2 Receptor, GATA-6 Activation, and FasL-Fas Engagement

(2009) Nicole Y. Tan et al.   CIRCULATION RESEARCH

Intracellular Signaling of LOX-1 in Endothelial Cell Apoptosis

(2009) Dayuan Li et al.   CIRCULATION RESEARCH

Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters

(2009) Hai-bo Wang et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose

(2009) Ashraf Taye et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Theaflavins retard human breast cancer cell migration by inhibiting NF-κB via p53-ROS cross-talk

(2009) Arghya Adhikary et al.   FEBS LETTERS

Reactive Oxygen Species-independent Oxidation of Thioredoxin in Hypoxia

(2009) Harish Muniyappa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rosuvastatin Attenuates Ang II—Mediated Cardiomyocyte Hypertrophy via Inhibition of LOX-1

(2009) Bum-Yong Kang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

SIRT1: A novel target to prevent atherosclerosis

(2009) Wei Yu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+signaling pathways in endothelial cells

(2009) Nobuo Sakamoto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Relationship of Oxidized Phospholipids and Biomarkers of Oxidized Low-Density Lipoprotein With Cardiovascular Risk Factors, Inflammatory Biomarkers, and Effect of Statin Therapy in Patients With Acute Coronary Syndromes

(2009) Alexander E. Fraley et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer

(2009) Toshiro Migita et al.   JNCI-Journal of the National Cancer Institute

Deletion of LOX-1 attenuates renal injury following angiotensin II infusion

(2009) Changping Hu et al.   KIDNEY INTERNATIONAL

Oxidative Stress and Hypertension

(2009) David G. Harrison et al.   MEDICAL CLINICS OF NORTH AMERICA

Association of soluble intercellular adhesion molecule–1 with insulin resistance and metabolic syndrome in Taiwanese

(2009) Lung-An Hsu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Angiotensin type 2 receptor-mediated apoptosis of human prostate cancer cells

(2009) H. Li et al.   MOLECULAR CANCER THERAPEUTICS

Weight, Dietary Behavior, and Physical Activity in Childhood and Adolescence: Implications for Adult Cancer Risk

(2009) Bernard F. Fuemmeler et al.   Obesity Facts

Redox regulation of anoikis resistance of metastatic prostate cancer cells: key role for Src and EGFR-mediated pro-survival signals

(2009) E Giannoni et al.   ONCOGENE

HIF2  inhibition promotes p53 pathway activity, tumor cell death, and radiation responses

(2009) J. A. Bertout et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat Shock Proteins in Cancer: Signaling Pathways, Tumor Markers and Molecular Targets in Liver Malignancy

(2009) Wen Lu et al.   PROTEIN AND PEPTIDE LETTERS

Effect of renin inhibition and AT1R blockade on myocardial remodeling in the transgenic Ren2 rat

(2008) Adam Whaley-Connell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The lectin-like oxidized low-density-lipoprotein receptor: a pro-inflammatory factor in vascular disease

(2008) Sarah Dunn et al.   BIOCHEMICAL JOURNAL

p53 hot-spot mutants increase tumor vascularization via ROS-mediated activation of the HIF1/VEGF-A pathway

(2008) N.V. Khromova et al.   CANCER LETTERS

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

Understanding tumor endothelial cell abnormalities to develop ideal anti-angiogenic therapies

(2008) Kyoko Hida et al.   CANCER SCIENCE

LOX-1 deletion decreases collagen accumulation in atherosclerotic plaque in low-density lipoprotein receptor knockout mice fed a high-cholesterol diet

(2008) C. Hu et al.   CARDIOVASCULAR RESEARCH

Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone

(2008) Yi Lu et al.   CLINICAL & EXPERIMENTAL METASTASIS

Oxidized LDL Receptor LOX-1 Binds to C-Reactive Protein and Mediates Its Vascular Effects

(2008) Y. Fujita et al.   CLINICAL CHEMISTRY

Arterial compliance and endothelium-dependent vasodilation are independently related to coronary risk in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study

(2008) Lars Lind   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

Modulation of Angiotensin II–Mediated Hypertension and Cardiac Remodeling by Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Deletion

(2008) Changping Hu et al.   HYPERTENSION

Heat shock proteins: Stress proteins with Janus-like properties in cancer

(2008) Stuart K. Calderwood et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

LOX-1 Receptor Blockade Abrogates oxLDL-induced Oxidative DNA Damage and Prevents Activation of the Transcriptional Repressor Oct-1 in Human Coronary Arterial Endothelium

(2008) Thomas Thum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beneficial Effects of Resveratrol on Atherosclerosis

(2008) Enguo Fan et al.   JOURNAL OF MEDICINAL FOOD

Role of angiotensin II AT1 receptor activation in cardiovascular diseases

(2008) Sandrine Billet et al.   KIDNEY INTERNATIONAL

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

AT2 receptors: Functional relevance in cardiovascular disease

(2008) Emma S. Jones et al.   PHARMACOLOGY & THERAPEUTICS

CD44v4 Is a Major E-Selectin Ligand that Mediates Breast Cancer Cell Transendothelial Migration

(2008) Ke Zen et al.   PLoS One

Obesity and cancer

(2008) Tobias Pischon et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Over-expression of angiotensin II type 2 receptor (agtr2) reduces atherogenesis and modulates LOX-1, endothelial nitric oxide synthase and heme-oxygenase-1 expression

(2007) Changping Hu et al.   ATHEROSCLEROSIS

RETRACTED: Redox regulation of resveratrol-mediated switching of death signal into survival signal

(2007) Samarjit Das et al.   FREE RADICAL BIOLOGY AND MEDICINE