Fatty Acid Synthase: A Metabolic Enzyme and Candidate Oncogene in Prostate Cancer

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells

(2010) A. Vazquez-Martin et al.   CELL PROLIFERATION

Mechanisms of apoptosis resistance and treatment strategies to overcome them in hormone-refractory prostate cancer

(2008) Robert G. Uzzo et al.   CANCER

Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

(2008) E. Furuta et al.   CANCER RESEARCH

Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the β-ketoacyl reductase reaction

(2008) María Jesús Vázquez et al.   FEBS Journal

Fatty acid synthase inhibition with Orlistat promotes apoptosis and reduces cell growth and lymph node metastasis in a mouse melanoma model

(2008) Marco A. Carvalho et al.   INTERNATIONAL JOURNAL OF CANCER

Vitamins E and C in the Prevention of Cardiovascular Disease in Men

(2008) Howard D. Sesso   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Synthesis of Novel β-Lactone Inhibitors of Fatty Acid Synthase

(2008) Robyn D. Richardson et al.   JOURNAL OF MEDICINAL CHEMISTRY

1-11C-Acetate as a PET Radiopharmaceutical for Imaging Fatty Acid Synthase Expression in Prostate Cancer

(2008) A. L. Vavere et al.   JOURNAL OF NUCLEAR MEDICINE

Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis

(2008) Jing Ma et al.   LANCET ONCOLOGY

A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction

(2008) H. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Multiple newly identified loci associated with prostate cancer susceptibility

(2008) Rosalind A Eeles et al.   NATURE GENETICS

The Crystal Structure of a Mammalian Fatty Acid Synthase

(2008) T. Maier et al.   SCIENCE