Recent Progresses in Phototherapy-Synergized Cancer Immunotherapy

Enhanced Immunotherapy Based on Photodynamic Therapy for Both Primary and Lung Metastasis Tumor Eradication

(2018) Wen Song et al.   ACS Nano

Enhancing Both Biodegradability and Efficacy of Semiconducting Polymer Nanoparticles for Photoacoustic Imaging and Photothermal Therapy

(2018) Yan Lyu et al.   ACS Nano

Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration

(2018) Liangliang Dai et al.   ADVANCED FUNCTIONAL MATERIALS

Antigen-Directed Fabrication of a Multifunctional Nanovaccine with Ultrahigh Antigen Loading Efficiency for Tumor Photothermal-Immunotherapy

(2018) Jinbin Pan et al.   ADVANCED MATERIALS

Dual-Peak Absorbing Semiconducting Copolymer Nanoparticles for First and Second Near-Infrared Window Photothermal Therapy: A Comparative Study

(2018) Yuyan Jiang et al.   ADVANCED MATERIALS

Temperature-Correlated Afterglow of a Semiconducting Polymer Nanococktail for Imaging-Guided Photothermal Therapy

(2018) Xu Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Macrotheranostic Probe with Disease-Activated Near-Infrared Fluorescence, Photoacoustic, and Photothermal Signals for Imaging-Guided Therapy

(2018) Xu Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Semiconducting Polymer Nanoenzymes with Photothermic Activity for Enhanced Cancer Therapy

(2018) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progress on semiconducting polymer nanoparticles for molecular imaging and cancer phototherapy

(2018) Jingchao Li et al.   BIOMATERIALS

Near-infrared photoimmunotherapy targeting EGFR-Shedding new light on glioblastoma treatment

(2018) Thomas A. Burley et al.   INTERNATIONAL JOURNAL OF CANCER

Immunogenic Apoptosis as a Novel Tool for Anticancer Vaccine Development

(2018) Barbara Montico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PEGylated magnetic Prussian blue nanoparticles as a multifunctional therapeutic agent for combined targeted photothermal ablation and pH-triggered chemotherapy of tumour cells

(2018) Peng Xue et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

The perfect personalized cancer therapy: cancer vaccines against neoantigens

(2018) Luigi Aurisicchio et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nanoscale Metal–Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer Immunotherapy

(2018) Guangxu Lan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near Infrared Photoimmunotherapy with Combined Exposure of External and Interstitial Light Sources

(2018) Yasuhiro Maruoka et al.   MOLECULAR PHARMACEUTICS

Semiconducting Photothermal Nanoagonist for Remote-Controlled Specific Cancer Therapy

(2018) Xu Zhen et al.   NANO LETTERS

The market for chimeric antigen receptor T cell therapies

(2018) Amy Yip et al.   NATURE REVIEWS DRUG DISCOVERY

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors

(2018) Tingting Wang et al.   Nature Communications

Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer

(2018) Jutaek Nam et al.   Nature Communications

An Endogenous Vaccine Based on Fluorophores and Multivalent Immunoadjuvants Regulates Tumor Micro-Environment for Synergistic Photothermal and Immunotherapy

(2018) Ling Li et al.   Theranostics

Photosensitizer-induced self-assembly of antigens as nanovaccines for cancer immunotherapy

(2018) F. Q. Cao et al.   Biomaterials Science

Advanced smart-photosensitizers for more effective cancer treatment

(2018) Wooram Park et al.   Biomaterials Science

Recent progress in the development of near-infrared organic photothermal and photodynamic nanotherapeutics

(2018) Houjuan Zhu et al.   Biomaterials Science

Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy

(2018) Jinrong Peng et al.   Advanced Science

The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia

(2017) Su-Fern Tan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Oxygenic Hybrid Semiconducting Nanoparticles for Enhanced Photodynamic Therapy

(2017) Houjuan Zhu et al.   NANO LETTERS

Prussian blue nanoparticle-based photothermal therapy combined with checkpoint inhibition for photothermal immunotherapy of neuroblastoma

(2017) Juliana Cano-Mejia et al.   Nanomedicine-Nanotechnology Biology and Medicine

Immunotherapy: Cancer vaccines on the move

(2017) Jacques Banchereau et al.   Nature Reviews Clinical Oncology

Calreticulin is an effective immunologic adjuvant to tumor-associated antigens

(2017) Jun Wang et al.   Experimental and Therapeutic Medicine

Polymer nanoparticles with high photothermal conversion efficiency as robust photoacoustic and thermal theranostics

(2017) Liang Guo et al.   Journal of Materials Chemistry B

Photodynamic-Immune Checkpoint Therapy Eradicates Local and Distant Tumors by CD8 + T Cells

(2017) Jan Willem Kleinovink et al.   Cancer Immunology Research

Anticancer actions of lysosomally targeted inhibitor, LCL521, of acid ceramidase

(2017) Aiping Bai et al.   PLoS One

Photothermal therapeutic application of gold nanorods-porphyrin-trastuzumab complexes in HER2-positive breast cancer

(2017) Xinmei Kang et al.   Scientific Reports

Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresectable and Metastatic Cancers

(2017) Yang Liu et al.   Scientific Reports

CTLA-4 and PD-1 Pathways

(2016) Elizabeth I. Buchbinder et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Recent advances in different modal imaging-guided photothermal therapy

(2016) Qiwen Chen et al.   BIOMATERIALS

Oncolytic virus therapy: A new era of cancer treatment at dawn

(2016) Hiroshi Fukuhara et al.   CANCER SCIENCE

Therapeutic hyperthermia: The old, the new, and the upcoming

(2016) Matthew Mallory et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Photodynamic-therapy Activates Immune Response by disrupting Immunity Homeostasis of Tumor Cells, which Generates Vaccine for Cancer Therapy

(2016) Yuanhong Zheng et al.   International Journal of Biological Sciences

Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine

(2016) Mladen Korbelik et al.   INTERNATIONAL JOURNAL OF CANCER

Photodynamic Therapy Mediated by Nontoxic Core–Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer

(2016) Xiaopin Duan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chlorin-Based Nanoscale Metal–Organic Framework Systemically Rejects Colorectal Cancers via Synergistic Photodynamic Therapy and Checkpoint Blockade Immunotherapy

(2016) Kuangda Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Acid-Activatable Versatile Micelleplexes for PD-L1 Blockade-Enhanced Cancer Photodynamic Immunotherapy

(2016) Dangge Wang et al.   NANO LETTERS

Spatially selective depletion of tumor-associated regulatory T cells with near-infrared photoimmunotherapy

(2016) Kazuhide Sato et al.   Science Translational Medicine

PD-L1 expression in human cancers and its association with clinical outcomes

(2016) Jinming Yu et al.   OncoTargets and Therapy

Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy

(2016) Chunbai He et al.   Nature Communications

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Enhanced Anti-Tumor Efficacy through a Combination of Integrin αvβ6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition

(2016) Liquan Gao et al.   Theranostics

Mreg Activity in Tumor Response to Photodynamic Therapy and Photodynamic Therapy-Generated Cancer Vaccines

(2016) Mladen Korbelik et al.   Cancers

Near-infrared labeled, ovalbumin loaded polymeric nanoparticles based on a hydrophilic polyester as model vaccine: In vivo tracking and evaluation of antigen-specific CD8 + T cell immune response

(2015) Sima Rahimian et al.   BIOMATERIALS

PEDOT nanocomposites mediated dual-modal photodynamic and photothermal targeted sterilization in both NIR I and II window

(2015) Luoyuan Li et al.   BIOMATERIALS

Semimetal nanomaterials of antimony as highly efficient agent for photoacoustic imaging and photothermal therapy

(2015) Wanwan Li et al.   BIOMATERIALS

Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors

(2015) Jingchao Li et al.   BIOMATERIALS

InCVAX – A novel strategy for treatment of late-stage, metastatic cancers through photoimmunotherapy induced tumor-specific immunity

(2015) Feifan Zhou et al.   CANCER LETTERS

Anti-tumor immunity of BAM-SiPc-mediated vascular photodynamic therapy in a BALB/c mouse model

(2015) Hing-Yuen Yeung et al.   Cellular & Molecular Immunology

Combination of Photodynamic Therapy and Specific Immunotherapy Efficiently Eradicates Established Tumors

(2015) J. W. Kleinovink et al.   CLINICAL CANCER RESEARCH

Photodynamic Therapy-mediated Cancer Vaccination Enhances Stem-like Phenotype and Immune Escape, Which Can Be Blocked by Thrombospondin-1 Signaling through CD47 Receptor Protein

(2015) Yuanhong Zheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pooled Analysis of Long-Term Survival Data From Phase II and Phase III Trials of Ipilimumab in Unresectable or Metastatic Melanoma

(2015) Dirk Schadendorf et al.   JOURNAL OF CLINICAL ONCOLOGY

IR 820 dye encapsulated in polycaprolactone glycol chitosan: Poloxamer blend nanoparticles for photo immunotherapy for breast cancer

(2015) Piyush Kumar et al.   Materials Science & Engineering C-Materials for Biological Applications

Nanomedicine for targeted photothermal cancer therapy: where are we now?

(2015) Feng Chen et al.   Nanomedicine

Combination cancer immunotherapies tailored to the tumour microenvironment

(2015) Mark J. Smyth et al.   Nature Reviews Clinical Oncology

Combination cancer immunotherapy and new immunomodulatory targets

(2015) Kathleen M. Mahoney et al.   NATURE REVIEWS DRUG DISCOVERY

Polypyrrole Composite Nanoparticles with Morphology-Dependent Photothermal Effect and Immunological Responses

(2015) Ye Tian et al.   Small

Calreticulin as Cancer Treatment Adjuvant: Combination with Photodynamic Therapy and Photodynamic Therapy-Generated Vaccines

(2015) Mladen Korbelik et al.   Frontiers in Oncology

Nanoparticle-Based Immunotherapy for Cancer

(2014) Kun Shao et al.   ACS Nano

Combinatorial Photothermal and Immuno Cancer Therapy Using Chitosan-Coated Hollow Copper Sulfide Nanoparticles

(2014) Liangran Guo et al.   ACS Nano

Immunological Responses Triggered by Photothermal Therapy with Carbon Nanotubes in Combination with Anti-CTLA-4 Therapy to Inhibit Cancer Metastasis

(2014) Chao Wang et al.   ADVANCED MATERIALS

Engineered, self-assembled near-infrared photothermal agents for combined tumor immunotherapy and chemo-photothermal therapy

(2014) Yu Tao et al.   BIOMATERIALS

Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer

(2014) M T Huggett et al.   BRITISH JOURNAL OF CANCER

Functional Nanomaterials for Phototherapies of Cancer

(2014) Liang Cheng et al.   CHEMICAL REVIEWS

Regulatory T cells in cancer immunotherapy

(2014) Hiroyoshi Nishikawa et al.   CURRENT OPINION IN IMMUNOLOGY

Various ways to improve whole cancer cell vaccines

(2014) Laetitia Cicchelero et al.   Expert Review of Vaccines

Local tumour hyperthermia as immunotherapy for metastatic cancer

(2014) Seiko Toraya-Brown et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Surface Plasmon Resonance Enhanced Light Absorption and Photothermal Therapy in the Second Near-Infrared Window

(2014) Xianguang Ding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Local hyperthermia treatment of tumors induces CD8+ T cell-mediated resistance against distal and secondary tumors

(2014) Seiko Toraya-Brown et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cu7.2S4 nanocrystals: a novel photothermal agent with a 56.7% photothermal conversion efficiency for photothermal therapy of cancer cells

(2014) Bo Li et al.   Nanoscale

Cancer/Testis Antigen HCA587-Derived Long Peptide Vaccine Generates Potent Immunologic Responses and Antitumor Effects in Mouse Model

(2014) Lijie Zhang et al.   ONCOLOGY RESEARCH

Rose Bengal Acetate PhotoDynamic Therapy (RBAc-PDT) Induces Exposure and Release of Damage-Associated Molecular Patterns (DAMPs) in Human HeLa Cells

(2014) Elisa Panzarini et al.   PLoS One

Prussian blue nanoparticles for laser-induced photothermal therapy of tumors

(2014) Hilary A. Hoffman et al.   RSC Advances

Au Nanorod Design as Light-Absorber in the First and Second Biological Near-Infrared Windows for in Vivo Photothermal Therapy

(2013) Ming-Fong Tsai et al.   ACS Nano

Ultra-Low Doses of Chirality Sorted (6,5) Carbon Nanotubes for Simultaneous Tumor Imaging and Photothermal Therapy

(2013) Alexander L. Antaris et al.   ACS Nano

NIR photothermal therapy using polyaniline nanoparticles

(2013) Jing Zhou et al.   BIOMATERIALS

Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance

(2013) Agnieszka Kaczmarek et al.   IMMUNITY

CpG oligodeoxynucleotide as immune adjuvant enhances photodynamic therapy response in murine metastatic breast cancer

(2013) Yumin Xia et al.   Journal of Biophotonics

Generation of an effective anti-lung cancer vaccine by DTPP-mediated photodynamic therapy and mechanistic studies

(2013) Liqing Zheng et al.   LASERS IN MEDICAL SCIENCE

Gold nanoparticle mediated cancer immunotherapy

(2013) Joao Paulo Mattos Almeida et al.   Nanomedicine-Nanotechnology Biology and Medicine

Long peptide-based cancer immunotherapy targeting tumor antigen-specific CD4+and CD8+T cells

(2013) Yusuke Tomita et al.   OncoImmunology

Antitumor immunologically modified carbon nanotubes for photothermal therapy

(2012) Feifan Zhou et al.   BIOMATERIALS

Photodynamic therapy–generated cancer vaccine elicits acute phase and hormonal response in treated mice

(2012) Mladen Korbelik et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Nanomaterials formulations for photothermal and photodynamic therapy of cancer

(2012) Edakkattuparambil Sidharth Shibu et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS

TAT Peptide-Functionalized Gold Nanostars: Enhanced Intracellular Delivery and Efficient NIR Photothermal Therapy Using Ultralow Irradiance

(2012) Hsiangkuo Yuan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor Immunotherapy Directed at PD-1

(2012) Antoni Ribas   NEW ENGLAND JOURNAL OF MEDICINE

Clinical effects of in situ photoimmunotherapy on late-stage melanoma patients

(2011) Xiaosong Li et al.   CANCER BIOLOGY & THERAPY

CpG DNA as a vaccine adjuvant

(2011) Christian Bode et al.   Expert Review of Vaccines

Chemokine-Containing Exosomes Are Released from Heat-Stressed Tumor Cells via Lipid Raft-Dependent Pathway and Act as Efficient Tumor Vaccine

(2011) T. Chen et al.   JOURNAL OF IMMUNOLOGY

IDO: more than an enzyme

(2011) WanJun Chen   NATURE IMMUNOLOGY

Cancer vaccines generated by photodynamic therapy

(2011) Mladen Korbelik   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

In situ real-time investigation of cancer cell photothermolysis mediated by excited gold nanorod surface plasmons

(2010) Cheng-Lung Chen et al.   BIOMATERIALS

Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release

(2010) Akiko Sato et al.   CANCER SCIENCE

Stimulation of anti-tumor immunity by photodynamic therapy

(2010) Pawel Mroz et al.   Expert Review of Clinical Immunology

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Photodynamic Therapy of Tumors Can Lead to Development of Systemic Antigen-Specific Immune Response

(2010) Pawel Mroz et al.   PLoS One

CpG Oligodeoxyneucleotides as TLR9 Agonists

(2009) Yanal M. Murad et al.   BIODRUGS

Recent Advances in Cancer Therapy: An Overview

(2009) A. Urruticoechea et al.   CURRENT PHARMACEUTICAL DESIGN

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy

(2009) Xiang Liu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

CD20 deficiency in humans results in impaired T cell–independent antibody responses

(2009) Taco W. Kuijpers et al.   JOURNAL OF CLINICAL INVESTIGATION

Second window for in vivo imaging

(2009) Andrew M. Smith et al.   Nature Nanotechnology

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Phase I Immunotherapeutic Trial with Long Peptides Spanning the E6 and E7 Sequences of High-Risk Human Papillomavirus 16 in End-Stage Cervical Cancer Patients Shows Low Toxicity and Robust Immunogenicity

(2008) G. G. Kenter et al.   CLINICAL CANCER RESEARCH

CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

(2008) J. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA