Various ways to improve whole cancer cell vaccines

Agonist Antibodies to TNFR Molecules That Costimulate T and NK Cells

(2013) I. Melero et al.   CLINICAL CANCER RESEARCH

Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion

(2013) Yared Hailemichael et al.   NATURE MEDICINE

Antigen cross-presentation by dendritic cell subsets: one general or all sergeants?

(2013) Stefan Nierkens et al.   TRENDS IN IMMUNOLOGY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Increasing the efficacy of tumor cell vaccines by enhancing cross priming

(2012) Brian M. Andersen et al.   CANCER LETTERS

Cancer Stem Cell Vaccination Confers Significant Antitumor Immunity

(2012) N. Ning et al.   CANCER RESEARCH

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

(2012) M. Velasco-Velazquez et al.   CANCER RESEARCH

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

(2012) Hidekazu Kameshima et al.   CANCER SCIENCE

Cytotoxic Chemotherapy and CD4+ Effector T Cells: An Emerging Alliance for Durable Antitumor Effects

(2012) Zhi-Chun Ding et al.   Clinical & Developmental Immunology

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Strategies for Enhancing Vaccine-Induced CTL Antitumor Immune Responses

(2012) Xin Yong et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Targeting Costimulatory Molecules to Improve Antitumor Immunity

(2012) Daria Capece et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Cancer therapy and vaccination

(2012) Hamdy A.A. Aly   JOURNAL OF IMMUNOLOGICAL METHODS

Vaccine Injection Site Matters: Qualitative and Quantitative Defects in CD8 T Cells Primed as a Function of Proximity to the Tumor in a Murine Glioma Model

(2012) J. R. Ohlfest et al.   JOURNAL OF IMMUNOLOGY

The Systematic Study of the Electroporation and Electrofusion of B16-F1 and CHO Cells in Isotonic and Hypotonic Buffer

(2012) Marko Usaj et al.   JOURNAL OF MEMBRANE BIOLOGY

Therapeutic Cancer Vaccines: Current Status and Moving Forward

(2012) J. Schlom   JNCI-Journal of the National Cancer Institute

Immunotherapy Against HPV16/18 Generates Potent TH1 and Cytotoxic Cellular Immune Responses

(2012) M. L. Bagarazzi et al.   Science Translational Medicine

Dendritic/Tumor Fusion Cells as Cancer Vaccines

(2012) David Avigan et al.   SEMINARS IN ONCOLOGY

T cell vaccinology: Exploring the known unknowns

(2012) Matt A. Burchill et al.   VACCINE

Yessotoxin as a Tool to Study Induction of Multiple Cell Death Pathways

(2012) Mónica Suárez Korsnes   Toxins

Targeting cancer stem cells via dendritic-cell vaccination

(2012) Seagal Teitz-Tennenbaum et al.   OncoImmunology

Loss-of-function alleles ofP2RX7andTLR4fail to affect the response to chemotherapy in non-small cell lung cancer

(2012) Erika Vacchelli et al.   OncoImmunology

Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy

(2011) Oliver Kepp et al.   CANCER AND METASTASIS REVIEWS

The CD40 agonist antibody CP-870,893 enhances dendritic cell and B-cell activity and promotes anti-tumor efficacy in SCID-hu mice

(2011) Ronald P. Gladue et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Monocyte-derived DC maturation strategies and related pathways: a transcriptional view

(2011) Luciano Castiello et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Beyond Cancer Vaccines

(2011) Michael Postow et al.   CANCER JOURNAL

Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response

(2011) J. Fucikova et al.   CANCER RESEARCH

Regulation of immune cell function and differentiation by the NKG2D receptor

(2011) Biljana Zafirova et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Potentiation strategies of dendritic cell-based antitumor vaccines: combinational therapy takes the front seat

(2011) Monireh Torabi-Rahvar et al.   DRUG DISCOVERY TODAY

NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d

(2011) Carlotta Kuylenstierna et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adjuvants for Enhancing the Immunogenicity of Whole Tumor Cell Vaccines

(2011) Cheryl Lai-Lai Chiang et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Recent Developments in Cancer Vaccines

(2011) K. Palucka et al.   JOURNAL OF IMMUNOLOGY

The iSBTc/SITC primer on tumor immunology and biological therapy of cancer: a summary of the 2010 program

(2011) James M Balwit et al.   Journal of Translational Medicine

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Cancer immunotherapy – revisited

(2011) W. Joost Lesterhuis et al.   NATURE REVIEWS DRUG DISCOVERY

Dendritic Cell Based Tumor Vaccination in Prostate and Renal Cell Cancer: A Systematic Review and Meta-Analysis

(2011) Andreas Draube et al.   PLoS One

Monitoring the Systemic Human Memory B Cell Compartment of Melanoma Patients for Anti-Tumor IgG Antibodies

(2011) Amy E. Gilbert et al.   PLoS One

Harnessing Dendritic Cells for Tumor Antigen Presentation

(2011) Stefan Nierkens et al.   Cancers

V-fusion: a convenient, nontoxic method for cell fusion

(2010) Amy Gottesman et al.   BIOTECHNIQUES

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model

(2010) Kimberley A. Stannard et al.   CANCER LETTERS

Tumor Cell Death and ATP Release Prime Dendritic Cells and Efficient Anticancer Immunity

(2010) L. Aymeric et al.   CANCER RESEARCH

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

Targeting inhibitory pathways in cancer immunotherapy

(2010) Marcio O Lasaro et al.   CURRENT OPINION IN IMMUNOLOGY

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

Therapeutic cancer vaccines: are we there yet?

(2010) Christopher A. Klebanoff et al.   IMMUNOLOGICAL REVIEWS

High hydrostatic pressure treatment generates inactivated mammalian tumor cells with immunogeneic features

(2010) E. M. Weiss et al.   Journal of Immunotoxicology

The Histone Deacetylase Inhibitor, Vorinostat, Reduces Tumor Growth at the Metastatic Bone Site and Associated Osteolysis, but Promotes Normal Bone Loss

(2010) J. Pratap et al.   MOLECULAR CANCER THERAPEUTICS

Epigenetic modifications as therapeutic targets

(2010) Theresa K Kelly et al.   NATURE BIOTECHNOLOGY

Whole tumor antigen vaccines

(2010) Cheryl Lai-Lai Chiang et al.   SEMINARS IN IMMUNOLOGY

Profound CD8+ T cell immunity elicited by sequential daily immunization with exogenous antigen plus the TLR3 agonist poly(I:C)

(2010) Darin A. Wick et al.   VACCINE

TLR-based immune adjuvants

(2010) Folkert Steinhagen et al.   VACCINE

Immunogenic cell death modalities and their impact on cancer treatment

(2009) Oliver Kepp et al.   APOPTOSIS

Arginase: an emerging key player in the mammalian immune system

(2009) Markus Munder   BRITISH JOURNAL OF PHARMACOLOGY

Recent advances in arginine metabolism: roles and regulation of the arginases

(2009) Sidney M Morris Jr   BRITISH JOURNAL OF PHARMACOLOGY

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Antigen loading of DCs with irradiated apoptotic tumor cells induces improved anti-tumor immunity compared to other approaches

(2009) Terry J. Fry et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Patient-derived renal cell carcinoma cells fused with allogeneic dendritic cells elicit anti-tumor activity: in vitro results and clinical responses

(2009) Jun Zhou et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Allogeneic GM-CSF-secreting tumor cell immunotherapies generate potent anti-tumor responses comparable to autologous tumor cell immunotherapies

(2009) Betty Li et al.   CLINICAL IMMUNOLOGY

Immunosuppressive Myeloid-Derived Suppressor Cells Can Be Converted into Immunogenic APCs with the Help of Activated NKT Cells: An Alternative Cell-Based Antitumor Vaccine

(2009) H.-J. Ko et al.   JOURNAL OF IMMUNOLOGY

AnnexinA5 renders dead tumor cells immunogenic—implications for multimodal cancer therapies

(2009) Benjamin Frey et al.   Journal of Immunotoxicology

Review of clinical studies on dendritic cell-based vaccination of patients with malignant melanoma: assessment of correlation between clinical response and vaccine parameters

(2008) Lotte Engell-Noerregaard et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Cancer chemotherapy: not only a direct cytotoxic effect, but also an adjuvant for antitumor immunity

(2008) Cédric Ménard et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines

(2008) Tanja D. de Gruijl et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Effective treatment of spontaneous metastases derived from a poorly immunogenic murine mammary carcinoma by combined dendritic–tumor hybrid vaccination and adoptive transfer of sensitized T cells

(2008) Hidemasa Tamai et al.   CLINICAL IMMUNOLOGY

B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer

(2008) Yu Liu et al.   CLINICAL IMMUNOLOGY

Introduction: the immune response against dying cells

(2008) Laurence Zitvogel et al.   CURRENT OPINION IN IMMUNOLOGY

Paradigm Shifts in Cancer Vaccine Therapy

(2008) Jeffrey Schlom et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Cell fusion: from hybridoma to dendritic cell-based vaccine

(2008) Jianlin Gong et al.   Expert Review of Vaccines

Principles of vaccination and possible development strategies for rational design

(2008) Claire J.P. Boog   IMMUNOLOGY LETTERS

The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway

(2008) S Wang   ONCOGENE

Immunogenicity of anthracyclines: moving towards more personalized medicine

(2008) Lionel Apetoh et al.   TRENDS IN MOLECULAR MEDICINE

An allogeneic hybrid-cell fusion vaccine against canine mammary cancer

(2008) R. Curtis Bird et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY