Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine

Inhibitors of Ceramidases

(2016) Essa M. Saied et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Targeting acid ceramidase sensitises head and neck cancer to cisplatin

(2016) Jong-Lyel Roh et al.   EUROPEAN JOURNAL OF CANCER

Immunoregulatory Cell Depletion Improves the Efficacy of Photodynamic Therapy-Generated Cancer Vaccines

(2015) Mladen Korbelik et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

C6-pyridinium ceramide sensitizes SCC17B human head and neck squamous cell carcinoma cells to photodynamic therapy

(2015) Nithin B. Boppana et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

The PERKs of damage-associated molecular patterns mediating cancer immunogenicity: From sensor to the plasma membrane and beyond

(2015) A.R. van Vliet et al.   SEMINARS IN CANCER BIOLOGY

Meta-analysis of organ-specific differences in the structure of the immune infiltrate in major malignancies

(2015) Gautier Stoll et al.   Oncotarget

Targeting (cellular) lysosomal acid ceramidase by B13: Design, synthesis and evaluation of novel DMG-B13 ester prodrugs

(2014) Aiping Bai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond

(2014) Christopher S. Garris et al.   IMMUNOLOGY

Ceramide and sphingosine-1-phosphate act as photodynamic therapy-elicited damage-associated molecular patterns: Cell surface exposure

(2014) Mladen Korbelik et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Retinoic Acid Increases Foxp3+ Regulatory T Cells and Inhibits Development of Th17 Cells by Enhancing TGF- -Driven Smad3 Signaling and Inhibiting IL-6 and IL-23 Receptor Expression

(2014) S. Xiao et al.   JOURNAL OF IMMUNOLOGY

Targeting S1P1 Receptor Protects against Murine Immunological Hepatic Injury through Myeloid-Derived Suppressor Cells

(2014) G. Liu et al.   JOURNAL OF IMMUNOLOGY

Consensus guidelines for the detection of immunogenic cell death

(2014) Oliver Kepp et al.   OncoImmunology

Radiation-induced acid ceramidase confers prostate cancer resistance and tumor relapse

(2013) Joseph C. Cheng et al.   JOURNAL OF CLINICAL INVESTIGATION

Bach2 Regulates Homeostasis of Foxp3+ Regulatory T Cells and Protects against Fatal Lung Disease in Mice

(2013) E. H. Kim et al.   JOURNAL OF IMMUNOLOGY

Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors

(2013) Mladen Korbelik et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Effective inhibition of acid and neutral ceramidases by novel B-13 and LCL-464 analogues

(2012) Krishna P. Bhabak et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Cyclophosphamide-induced Myeloid-derived Suppressor Cell Population Is Immunosuppressive But Not Identical to Myeloid-derived Suppressor Cells Induced By Growing TC-1 Tumors

(2012) Romana Mikyšková et al.   JOURNAL OF IMMUNOTHERAPY

Acid Ceramidase (ASAH1) Represses Steroidogenic Factor 1-Dependent Gene Transcription in H295R Human Adrenocortical Cells by Binding to the Receptor

(2012) N. C. Lucki et al.   MOLECULAR AND CELLULAR BIOLOGY

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages

(2011) Nadia M. Luheshi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cancer vaccines generated by photodynamic therapy

(2011) Mladen Korbelik   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Enhanced tumor cures after Foscan photodynamic therapy combined with the ceramide analog LCL29. Evidence from mouse squamous cell carcinomas for sphingolipids as biomarkers of treatment response

(2010) Separovic   INTERNATIONAL JOURNAL OF ONCOLOGY

The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells

(2010) Guangwei Liu et al.   NATURE IMMUNOLOGY

Functional Analysis of FOXP3

(2009) Jane H. Buckner et al.   Annals of the New York Academy of Sciences

Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy

(2009) Xiang Liu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Molecular Targeting of Acid Ceramidase: Implications to Cancer Therapy

(2008) Youssef Zeidan et al.   CURRENT DRUG TARGETS

Novel analogs of d-e-MAPP and B13. Part 1: Synthesis and evaluation as potential anticancer agents

(2007) Zdzislaw M. Szulc et al.   BIOORGANIC & MEDICINAL CHEMISTRY