Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy

Synthesis and bioevaluation of ω-N-amino analogs of B13

(2009) Aiping Bai et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Towards the definition of prostate cancer-related microRNAs: where are we now?

(2009) Paolo Gandellini et al.   TRENDS IN MOLECULAR MEDICINE

Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate

(2008) C MAO   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes

(2008) M. V. Shah et al.   BLOOD

Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias

(2008) W. J. Kim et al.   BLOOD

Cytotoxicity and acid ceramidase inhibitory activity of 2-substituted aminoethanol amides

(2008) Carmen Bedia et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Molecular Targeting of Acid Ceramidase: Implications to Cancer Therapy

(2008) Youssef Zeidan et al.   CURRENT DRUG TARGETS

Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

(2008) Sophie Pattingre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase I/II Study of Biweekly Paclitaxel and Radiation in Androgen-Ablated Locally Advanced Prostate Cancer

(2008) Nicholas J. Sanfilippo et al.   JOURNAL OF CLINICAL ONCOLOGY

Filamin A Links Sphingosine Kinase 1 and Sphingosine-1-Phosphate Receptor 1 at Lamellipodia To Orchestrate Cell Migration

(2008) M. Maceyka et al.   MOLECULAR AND CELLULAR BIOLOGY

Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models

(2008) D. Pchejetski et al.   MOLECULAR CANCER THERAPEUTICS

Acid Ceramidase Upregulation in Prostate Cancer Cells Confers Resistance to Radiation: AC Inhibition, a Potential Radiosensitizer

(2008) Ayman EM Mahdy et al.   MOLECULAR THERAPY

Novel analogs of d-e-MAPP and B13. Part 2: Signature effects on bioactive sphingolipids

(2007) Alicja Bielawska et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Novel analogs of d-e-MAPP and B13. Part 1: Synthesis and evaluation as potential anticancer agents

(2007) Zdzislaw M. Szulc et al.   BIOORGANIC & MEDICINAL CHEMISTRY