CpG DNA as a vaccine adjuvant

Improving the Immunogenicity of Pneumococcal Conjugate Vaccine in HIV‐Infected Adults with a Toll‐Like Receptor 9 Agonist Adjuvant: A Randomized, Controlled Trial

(2010) Ole S. Søgaard et al.   CLINICAL INFECTIOUS DISEASES

In Situ Vaccination With a TLR9 Agonist Induces Systemic Lymphoma Regression: A Phase I/II Study

(2010) Joshua D. Brody et al.   JOURNAL OF CLINICAL ONCOLOGY

Peptide Vaccine Induces Enhanced Tumor Growth Associated with Apoptosis Induction in CD8+ T Cells

(2010) D. Muraoka et al.   JOURNAL OF IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

A Novel Class of Immune-Stimulatory CpG Oligodeoxynucleotides Unifies High Potency in Type I Interferon Induction with Preferred Structural Properties

(2010) Ulrike Samulowitz et al.   OLIGONUCLEOTIDES

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

(2009) Jörg Vollmer et al.   ADVANCED DRUG DELIVERY REVIEWS

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

CpG-enhanced CD8+ T-cell responses to peptide immunization are severely inhibited by B cells

(2009) Michael G. Overstreet et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tumor-reactive CD8+T-cell responses after vaccination with NY-ESO-1 peptide, CpG 7909 and Montanide® ISA-51: Association with survival

(2009) Julia Karbach et al.   INTERNATIONAL JOURNAL OF CANCER

Inductive and suppressive networks regulate TLR9-dependent gene expression in vivo

(2009) Sven Klaschik et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neonatal Sublingual Vaccination with Salmonella Proteins and Adjuvant Cholera Toxin or CpG Oligodeoxynucleotides Induces Mucosal and Systemic Immunity in Mice

(2009) Ching-Feng Huang et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Short- and long-term changes in gene expression mediated by the activation of TLR9

(2009) Sven Klaschik et al.   MOLECULAR IMMUNOLOGY

A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel®+CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults

(2009) Issaka Sagara et al.   VACCINE

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali

(2009) Boubacar Traore et al.   VACCINE

TLR9 as a key receptor for the recognition of DNA☆

(2008) Y KUMAGAI et al.   ADVANCED DRUG DELIVERY REVIEWS

CpG Oligodeoxynucleotides Alter Lymphocyte and Dendritic Cell Trafficking in Humans

(2008) W. N. Haining et al.   CLINICAL CANCER RESEARCH

CPG 7909 Adjuvant plus Hepatitis B Virus Vaccination in HIV‐Infected Adults Achieves Long‐Term Seroprotection for Up to 5 Years

(2008) C. L. Cooper et al.   CLINICAL INFECTIOUS DISEASES

Accessing the therapeutic potential of immunostimulatory nucleic acids

(2008) Winfried Barchet et al.   CURRENT OPINION IN IMMUNOLOGY

Dendritic cells and innate defense against tumor cells

(2008) E ULLRICH et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Immunization With Analog Peptide in Combination With CpG and Montanide Expands Tumor Antigen-specific CD8+ T Cells in Melanoma Patients

(2008) Julien Fourcade et al.   JOURNAL OF IMMUNOTHERAPY

Sickle Cell Trait Is Associated with a Delayed Onset of Malaria: Implications for Time‐to‐Event Analysis in Clinical Studies of Malaria

(2008) Peter D. Crompton et al.   JOURNAL OF INFECTIOUS DISEASES

Dynavax trial halted

(2008) Laura DeFrancesco   NATURE BIOTECHNOLOGY

Phase 1 Trial of AMA1-C1/Alhydrogel plus CPG 7909: An Asexual Blood-Stage Vaccine for Plasmodium falciparum Malaria

(2008) Gregory E. D. Mullen et al.   PLoS One

In vivo oral administration effects of various oligodeoxynucleotides containing synthetic immunostimulatory motifs in the immune response to pseudorabies attenuated virus vaccine in newborn piglets

(2007) Zhang Linghua et al.   VACCINE