CNS macrophages and peripheral myeloid cells in brain tumours

TLR Ligands in the Local Treatment of Established Intracerebral Murine Gliomas

(2014) O. M. Grauer et al.   JOURNAL OF IMMUNOLOGY

GDNF mediates glioblastoma-induced microglia attraction but not astrogliosis

(2013) Min-Chi Ku et al.   ACTA NEUROPATHOLOGICA

Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma

(2013) Krishna P.L. Bhat et al.   CANCER CELL

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

(2013) Andrea Casazza et al.   CANCER CELL

miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

(2013) Jun Wei et al.   CANCER RESEARCH

The Endogenous Tryptophan Metabolite and NAD+ Precursor Quinolinic Acid Confers Resistance of Gliomas to Oxidative Stress

(2013) F. Sahm et al.   CANCER RESEARCH

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Acquired Resistance to Anti-VEGF Therapy in Glioblastoma Is Associated with a Mesenchymal Transition

(2013) Y. Piao et al.   CLINICAL CANCER RESEARCH

Proteins in Microglial Activation - Inputs and Outputs by Subsets

(2013) Uwe-Karsten Hanisch   CURRENT PROTEIN & PEPTIDE SCIENCE

Clinical trials in cellular immunotherapy for brain/CNS tumors

(2013) Jetan Badhiwala et al.   Expert Review of Neurotherapeutics

The A1 adenosine receptor as a new player in microglia physiology

(2013) L. Luongo et al.   GLIA

Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia

(2013) Aleksandra Ellert-Miklaszewska et al.   GLIA

Glioblastoma and Other Malignant Gliomas

(2013) Antonio Omuro   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex

(2013) C. L. Cunningham et al.   JOURNAL OF NEUROSCIENCE

Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response

(2013) Malgorzata Sielska et al.   JOURNAL OF PATHOLOGY

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells

(2013) Susobhan Sarkar et al.   NATURE NEUROSCIENCE

A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

(2013) Tobias Goldmann et al.   NATURE NEUROSCIENCE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

The microglial sensome revealed by direct RNA sequencing

(2013) Suzanne E Hickman et al.   NATURE NEUROSCIENCE

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2006-2010

(2013) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Minocycline selectively inhibits M1 polarization of microglia

(2013) K Kobayashi et al.   Cell Death & Disease

Immune Heterogeneity of Glioblastoma Subtypes: Extrapolation from the Cancer Genome Atlas

(2013) T. Doucette et al.   Cancer Immunology Research

Targeting Tregs in Malignant Brain Cancer: Overcoming IDO

(2013) Derek A. Wainwright et al.   Frontiers in Immunology

Adoptive Cell Therapies for Glioblastoma

(2013) Kevin Bielamowicz et al.   Frontiers in Oncology

The Tumor Microenvironment Strongly Impacts Master Transcriptional Regulators and Gene Expression Class of Glioblastoma

(2012) Lee A.D. Cooper et al.   AMERICAN JOURNAL OF PATHOLOGY

Biology, genetics and imaging of glial cell tumours

(2012) C Walker et al.   BRITISH JOURNAL OF RADIOLOGY

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

Impact of Temozolomide on Immune Response during Malignant Glioma Chemotherapy

(2012) Sadhak Sengupta et al.   Clinical & Developmental Immunology

Regulation of oxidative stress in long-lived lipopolysaccharide-activated microglia

(2012) Yoko S Kaneko et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Genomic Estimates of Aneuploid Content in Glioblastoma Multiforme and Improved Classification

(2012) B. Li et al.   CLINICAL CANCER RESEARCH

Development and homeostasis of “resident” myeloid cells: The case of the microglia

(2012) Elisa Gomez Perdiguero et al.   GLIA

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

The nucleotide-binding oligomerization domain-containing-2 ligand muramyl dipeptide enhances phagocytosis and intracellular killing of Escherichia coli K1 by Toll-like receptor agonists in microglial cells

(2012) Sandra Ribes et al.   JOURNAL OF NEUROIMMUNOLOGY

Microglia Modulate Hippocampal Neural Precursor Activity in Response to Exercise and Aging

(2012) J. Vukovic et al.   JOURNAL OF NEUROSCIENCE

Long-term outcomes for low-grade intracranial ganglioglioma: 30-year experience from the Mayo Clinic

(2012) Julia J. Compton et al.   JOURNAL OF NEUROSURGERY

Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer ‘if’ but ‘how’

(2012) Ravid Shechter et al.   JOURNAL OF PATHOLOGY

Unknown

(2012) Salvatore Coniglio et al.   MOLECULAR MEDICINE

Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype

(2012) Y. Piao et al.   NEURO-ONCOLOGY

Microglia in development: linking brain wiring to brain environment

(2012) Rosa C. Paolicelli et al.   Neuron Glia Biology

Review: Activation patterns of microglia and their identification in the human brain

(2012) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine A-induced cell death

(2012) I A Ciechomska et al.   ONCOGENE

Increased Microglia/Macrophage Gene Expression in a Subset of Adult and Pediatric Astrocytomas

(2012) Jane R. Engler et al.   PLoS One

Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation

(2012) H. Qin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathophysiology of astroglial purinergic signalling

(2012) Heike Franke et al.   Purinergic Signalling

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression

(2011) D.S. Markovic et al.   BRAIN BEHAVIOR AND IMMUNITY

Age related changes in microglial phenotype vary between CNS regions: Grey versus white matter differences

(2011) Adam D. Hart et al.   BRAIN BEHAVIOR AND IMMUNITY

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

(2011) Balázs Csóka et al.   FASEB JOURNAL

The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma

(2011) K. P. L. Bhat et al.   GENES & DEVELOPMENT

Tumor-secreted SDF-1 promotes glioma invasiveness and TAM tropism toward hypoxia in a murine astrocytoma model

(2011) Shu-Chi Wang et al.   LABORATORY INVESTIGATION

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling

(2011) Tuomas Tammela et al.   NATURE CELL BIOLOGY

Microglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation

(2011) Tim Kees et al.   NEURO-ONCOLOGY

Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia

(2011) V. L. Jacobs et al.   NEURO-ONCOLOGY

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Characteristics of the Alternative Phenotype of Microglia/Macrophages and its Modulation in Experimental Gliomas

(2011) Konrad Gabrusiewicz et al.   PLoS One

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

CX3CR1 promotes recruitment of human glioma-infiltrating microglia/macrophages (GIMs)

(2010) Janka Held-Feindt et al.   EXPERIMENTAL CELL RESEARCH

Cryptic activities of fibronectin fragments, particularly cryptic proteases

(2010) Maurice Pagano   Frontiers in Bioscience-Landmark

Glioma-initiating cells: A predominant role in microglia/macrophages tropism to glioma

(2010) Liang Yi et al.   JOURNAL OF NEUROIMMUNOLOGY

Immunotherapy coming of age: What will it take to make it standard of care for glioblastoma?

(2010) A. B. Heimberger et al.   NEURO-ONCOLOGY

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

(2010) Alexander Dityatev et al.   TRENDS IN NEUROSCIENCES

ATP stimulates chemokine production via a store-operated calcium entry pathway in C6 glioma cells

(2009) Nattinee Jantaratnotai et al.   BMC CANCER

TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma

(2009) Silvia Peñuelas et al.   CANCER CELL

The human brain in numbers: a linearly scaled-up primate brain

(2009) Suzana Herculano-Houzel   Frontiers in Human Neuroscience

Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice

(2009) Leying Zhang et al.   GLIA

Flow cytometry and in vitro analysis of human glioma–associated macrophages

(2009) Ian F. Parney et al.   JOURNAL OF NEUROSURGERY

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Antiangiogenic therapies for high-grade glioma

(2009) Andrew D. Norden et al.   Nature Reviews Neurology

Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion

(2009) D. S. Markovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of CTL Function among High-Avidity Tumor-Specific CD8+ T Cells following Tumor Infiltration

(2008) C. N. Janicki et al.   CANCER RESEARCH

Combating immunosuppression in glioma

(2008) Eleanor A Vega et al.   Future Oncology

CX3CL1 and CX3CR1 in the GL261 murine model of glioma: CX3CR1 deficiency does not impact tumor growth or infiltration of microglia and lymphocytes

(2008) Che Liu et al.   JOURNAL OF NEUROIMMUNOLOGY

Endothelial Cell Barrier Impairment Induced by Glioblastomas and Transforming Growth Factor β2Involves Matrix Metalloproteinases and Tight Junction Proteins

(2008) Hideyuki Ishihara et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Induction of prostaglandin E2 synthesis and microsomal prostaglandin E synthase–1 expression in murine microglia by glioma-derived soluble factors

(2008) Yoshiteru Nakano et al.   JOURNAL OF NEUROSURGERY

Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas

(2008) Y Komohara et al.   JOURNAL OF PATHOLOGY

Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas

(2008) E. C. Brantley et al.   MOLECULAR CANCER RESEARCH

Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead

(2007) V. W.M. van Hinsbergh et al.   CARDIOVASCULAR RESEARCH