Immunotherapy coming of age: What will it take to make it standard of care for glioblastoma?

Modulation of T-Cell Activation by Malignant Melanoma Initiating Cells

(2010) T. Schatton et al.   CANCER RESEARCH

Survival of Patients with Newly Diagnosed Glioblastoma Treated with Radiation and Temozolomide in Research Studies in the United States

(2010) S. A. Grossman et al.   CLINICAL CANCER RESEARCH

Glioma-Associated Cancer-Initiating Cells Induce Immunosuppression

(2010) J. Wei et al.   CLINICAL CANCER RESEARCH

Immunobiological Characterization of Cancer Stem Cells Isolated from Glioblastoma Patients

(2010) T. Di Tomaso et al.   CLINICAL CANCER RESEARCH

Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma

(2010) John H. Sampson et al.   JOURNAL OF CLINICAL ONCOLOGY

Glioblastoma Cancer-Initiating Cells Inhibit T-Cell Proliferation and Effector Responses by the Signal Transducers and Activators of Transcription 3 Pathway

(2010) J. Wei et al.   MOLECULAR CANCER THERAPEUTICS

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

(2010) Adam Wu et al.   NEURO-ONCOLOGY

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

(2010) F. Stephen Hodi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Brain metastases and subtypes of breast cancer

(2009) B. C. Pestalozzi   ANNALS OF ONCOLOGY

Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter?

(2009) S Postel-Vinay et al.   BRITISH JOURNAL OF CANCER

Recognition and Killing of Brain Tumor Stem-Like Initiating Cells by CD8+ Cytolytic T Cells

(2009) C. E. Brown et al.   CANCER RESEARCH

Efficacy of temozolomide as adjuvant chemotherapy after postsurgical radiotherapy alone for glioblastomas

(2009) Deok-Joo Rhee et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation

(2009) Alberto Mantovani et al.   HUMAN IMMUNOLOGY

Self-antigen–specific CD8+T cell precursor frequency determines the quality of the antitumor immune response

(2009) Gabrielle A. Rizzuto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tuberculosis Subunit Vaccination Provides Long-Term Protective Immunity Characterized by Multifunctional CD4 Memory T Cells

(2009) T. Lindenstrom et al.   JOURNAL OF IMMUNOLOGY

Anti-CTLA-4 therapy-related autoimmune hypophysitis in a melanoma patient

(2009) Katharina C. Kaehler et al.   MELANOMA RESEARCH

An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme

(2009) J. H. Sampson et al.   MOLECULAR CANCER THERAPEUTICS

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Lessons from 60 years of pharmaceutical innovation

(2009) Bernard Munos   NATURE REVIEWS DRUG DISCOVERY

Modulation of Angiogenic and Inflammatory Response in Glioblastoma by Hypoxia

(2009) Anastasia Murat et al.   PLoS One

Antigen-Specific T-Cell Response from Dendritic Cell Vaccination Using Cancer Stem-Like Cell-Associated Antigens

(2009) Qijin Xu et al.   STEM CELLS

Vaccination Elicits Correlated Immune and Clinical Responses in Glioblastoma Multiforme Patients

(2008) C. J. Wheeler et al.   CANCER RESEARCH

A Novel Inhibitor of Signal Transducers And Activators Of Transcription 3 Activation Is Efficacious Against Established Central Nervous System Melanoma and Inhibits Regulatory T Cells

(2008) L.-Y. Kong et al.   CLINICAL CANCER RESEARCH

Incidence and Prognostic Impact of FoxP3+ Regulatory T Cells in Human Gliomas

(2008) A. B. Heimberger et al.   CLINICAL CANCER RESEARCH

Postoperative Adjuvant Dendritic Cell-Based Immunotherapy in Patients with Relapsed Glioblastoma Multiforme

(2008) S. De Vleeschouwer et al.   CLINICAL CANCER RESEARCH

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics

(2008) Naoki Umemura et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tumor antigen precursor protein profiles of adult and pediatric brain tumors identify potential targets for immunotherapy

(2008) Jian Gang Zhang et al.   JOURNAL OF NEURO-ONCOLOGY

A phase II clinical trial of poly-ICLC with radiation for adult patients with newly diagnosed supratentorial glioblastoma: a North American Brain Tumor Consortium (NABTC01-05)

(2008) Nicholas Butowski et al.   JOURNAL OF NEURO-ONCOLOGY

CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit

(2008) J. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA