Hypoxic culture conditions enhance the generation of regulatory T cells

The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

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Th2 Lymphoproliferative Disorder of LatY136F Mutant Mice Unfolds Independently of TCR-MHC Engagement and Is Insensitive to the Action of Foxp3+ Regulatory T Cells

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Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

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Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells

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Hypoxia-induced and A2A adenosine receptor-independent T-cell suppression is short lived and easily reversible

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Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process

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Intratumor Hypoxia Promotes Immune Tolerance by Inducing Regulatory T Cells via TGF-β1 in Gastric Cancer

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Three Novel Acetylation Sites in the Foxp3 Transcription Factor Regulate the Suppressive Activity of Regulatory T Cells

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Adora2b Adenosine Receptor Engagement Enhances Regulatory T Cell Abundance during Endotoxin-Induced Pulmonary Inflammation

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Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa

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The development and immunosuppressive functions of CD4+ CD25+ FoxP3+ regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway

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Generation and Large-Scale Expansion of Human Inducible Regulatory T Cells That Suppress Graft-Versus-Host Disease

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Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets

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Hypoxia Potentiates Glioma-Mediated Immunosuppression

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Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1

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Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity

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mTOR signalling and metabolic regulation of T cell differentiation

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Metabolism in T cell activation and differentiation

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An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness

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SIRT1 Negatively Regulates the Mammalian Target of Rapamycin

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Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

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The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling

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Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization

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The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment

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The multiple facets of mTOR in immunity

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Critical role of IL-2 and TGF-β in generation, function and stabilization of Foxp3+CD4+ Treg

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Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α

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The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+cells

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PTEN Nuclear Localization Is Regulated by Oxidative Stress and Mediates p53-Dependent Tumor Suppression

(2008) C.-J. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

IL-2 signaling prevents T cell anergy by inhibiting the expression of anergy-inducing genes

(2008) Myrianne Duré et al.   MOLECULAR IMMUNOLOGY

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

(2008) S. Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of 2-hydroxyethidium in cellular systems: a unique marker product of superoxide and hydroethidine

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