Adora2b Adenosine Receptor Engagement Enhances Regulatory T Cell Abundance during Endotoxin-Induced Pulmonary Inflammation

Adenosine A2B receptor antagonist suppresses differentiation to regulatory T cells without suppressing activation of T cells

(2011) Hiroko Nakatsukasa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

(2011) Ming Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

The A2B Adenosine Receptor Promotes Th17 Differentiation via Stimulation of Dendritic Cell IL-6

(2011) J. M. Wilson et al.   JOURNAL OF IMMUNOLOGY

A2B Adenosine Receptor Blockade Enhances Macrophage-Mediated Bacterial Phagocytosis and Improves Polymicrobial Sepsis Survival in Mice

(2011) B. G. Belikoff et al.   JOURNAL OF IMMUNOLOGY

A2B Adenosine Receptor-Mediated Induction of IL-6 Promotes CKD

(2011) Y. Dai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Netrin-1 Dampens Pulmonary Inflammation during Acute Lung Injury

(2010) Valbona Mirakaj et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Extracellular Adenosine: A Safety Signal That Dampens Hypoxia-Induced Inflammation During Ischemia

(2010) Almut Grenz et al.   ANTIOXIDANTS & REDOX SIGNALING

IL-6: Regulator of Treg/Th17 balance

(2010) Akihiro Kimura et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Distinct Roles for the A2B Adenosine Receptor in Acute and Chronic Stages of Bleomycin-Induced Lung Injury

(2010) Y. Zhou et al.   JOURNAL OF IMMUNOLOGY

Signaling through the A2B Adenosine Receptor Dampens Endotoxin-Induced Acute Lung Injury

(2010) U. Schingnitz et al.   JOURNAL OF IMMUNOLOGY

Much Ado about Adenosine: Adenosine Synthesis and Function in Regulatory T Cell Biology

(2010) P. B. Ernst et al.   JOURNAL OF IMMUNOLOGY

A2B Adenosine Receptors Protect against Sepsis-Induced Mortality by Dampening Excessive Inflammation

(2010) B. Csoka et al.   JOURNAL OF IMMUNOLOGY

Detrimental effects of adenosine signaling in sickle cell disease

(2010) Yujin Zhang et al.   NATURE MEDICINE

CD4+CD25+Foxp3+ Regulatory T Cells Depletion May Attenuate the Development of Silica-Induced Lung Fibrosis in Mice

(2010) Fangwei Liu et al.   PLoS One

Attenuation of Chronic Pulmonary Inflammation in A2BAdenosine Receptor Knockout Mice

(2009) Rinat Zaynagetdinov et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Naringenin: A Potential Immunomodulator for Inhibiting Lung Fibrosis and Metastasis

(2009) G. Du et al.   CANCER RESEARCH

Antigen Specificity Is not Required for Modulation of Lung Allergic Responses by Naturally Occurring Regulatory T Cells

(2009) A. Joetham et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Regulatory T Cells Do Not Require Stimulation through Their TCR to Suppress

(2009) A. L. Szymczak-Workman et al.   JOURNAL OF IMMUNOLOGY

Enhanced Airway Inflammation and Remodeling in Adenosine Deaminase-Deficient Mice Lacking the A2B Adenosine Receptor

(2009) Y. Zhou et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: A2B Adenosine Receptor Signaling Provides Potent Protection during Intestinal Ischemia/Reperfusion Injury

(2009) M. L. Hart et al.   JOURNAL OF IMMUNOLOGY

The A2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells

(2009) J. M. Wilson et al.   JOURNAL OF IMMUNOLOGY

Contribution of Adenosine A2B Receptors to Inflammatory Parameters of Experimental Colitis

(2009) J.-S. Frick et al.   JOURNAL OF IMMUNOLOGY

Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses

(2009) Ye Zheng et al.   NATURE

Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia

(2009) Peter Rosenberger et al.   NATURE IMMUNOLOGY

Foxp3+ regulatory T cells: differentiation, specification, subphenotypes

(2009) Markus Feuerer et al.   NATURE IMMUNOLOGY

Hypoxia-Adenosinergic Immunosuppression: Tumor Protection by T Regulatory Cells and Cancerous Tissue Hypoxia

(2008) M. V. Sitkovsky et al.   CLINICAL CANCER RESEARCH

Selective induction of integrin β1 by hypoxia-inducible factor: implications for wound healing

(2008) Simon Keely et al.   FASEB JOURNAL

Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces

(2008) Yuri P. Rubtsov et al.   IMMUNITY

The Reno-Vascular A2B Adenosine Receptor Protects the Kidney from Ischemia

(2008) Almut Grenz et al.   PLOS MEDICINE

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY