Rapid Temporal Control of Foxp3 Protein Degradation by Sirtuin-1

Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs

(2010) Tatiana Akimova et al.   CLINICAL IMMUNOLOGY

Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function

(2010) Yan Xiao et al.   CURRENT OPINION IN IMMUNOLOGY

Nicotinamide phosphoribosyltransferase/sirtuin 1 pathway is involved in human immunodeficiency virus type 1 Tat-mediated long terminal repeat transactivation

(2010) Hong-Sheng Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization

(2009) J. van Loosdregt et al.   BLOOD

Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis

(2009) Sandra J. Saouaf et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Inhibition of HDAC9 Increases T Regulatory Cell Function and Prevents Colitis in Mice

(2009) Edwin F. de Zoeten et al.   GASTROENTEROLOGY

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

(2009) Jinping Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

sirt1-null mice develop an autoimmune-like condition

(2008) Jedon Sequeira et al.   EXPERIMENTAL CELL RESEARCH

TGF-  and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3

(2008) A. Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Potent and Stable Human CD4+ T Regulatory Cells by Activation-independent Expression of FOXP3

(2007) Sarah E Allan et al.   MOLECULAR THERAPY