Effects of Oleacein on High-Fat Diet-Dependent Steatosis, Weight Gain, and Insulin Resistance in Mice

Simple and efficient sustainable semi-synthesis of oleacein [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate] as potential additive for edible oils

(2018) Paola Costanzo et al.   FOOD CHEMISTRY

Critical Review on the Significance of Olive Phytochemicals in Plant Physiology and Human Health

(2017) Irene Gouvinhas et al.   MOLECULES

Metformin causes a futile intestinal–hepatic cycle which increases energy expenditure and slows down development of a type 2 diabetes-like state

(2017) Philipp Schommers et al.   Molecular Metabolism

Abdominal Obesity and Insulin Resistance in People Exposed to Moderate-to-High Levels of Dioxin

(2016) Jung-Wei Chang et al.   PLoS One

Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex

(2016) Jing Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of MEK1 Signaling Pathway in the Liver Ameliorates Insulin Resistance

(2016) Atsunori Ueyama et al.   Journal of Diabetes Research

Normocaloric Diet Restores Weight Gain and Insulin Sensitivity in Obese Mice

(2016) Giovanni Enrico Lombardo et al.   Frontiers in Endocrinology

Oral Administration of Oleuropein and Its Semisynthetic Peracetylated Derivative Prevents Hepatic Steatosis, Hyperinsulinemia, and Weight Gain in Mice Fed with High Fat Cafeteria Diet

(2015) Saverio Massimo Lepore et al.   International Journal of Endocrinology

Nutraceutical oleuropein supplementation prevents high fat diet-induced adiposity in mice

(2015) Inge van der Stelt et al.   Journal of Functional Foods

Cooperation between HMGA1, PDX-1, and MafA is Essential for Glucose-Induced Insulin Transcription in Pancreatic Beta Cells

(2015) Biagio Arcidiacono et al.   Frontiers in Endocrinology

Components of a standardised olive leaf dry extract (Ph. Eur.) promote hypothiocyanite production by lactoperoxidase

(2014) Jörg Flemmig et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Biomimetic synthesis and antioxidant evaluation of 3,4-DHPEA-EDA [2-(3,4-hydroxyphenyl) ethyl (3S,4E)-4-formyl-3-(2-oxoethyl)hex-4-enoate]

(2014) Monica Nardi et al.   FOOD CHEMISTRY

Effects of the Olive-Derived Polyphenol Oleuropein on Human Health

(2014) Barbara Barbaro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention

(2014) Shaodong Guo   JOURNAL OF ENDOCRINOLOGY

Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases

(2014) Stefania Bulotta et al.   Journal of Translational Medicine

Early Effects of a Hypocaloric, Mediterranean Diet on Laboratory Parameters in Obese Individuals

(2014) Marta Greco et al.   MEDIATORS OF INFLAMMATION

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

(2013) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glucose homeostasis can be differentially modulated by varying individual components of a western diet

(2013) Josephine M. Forbes et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Evidence That an HMGA1 Gene Variant Associates with Type 2 Diabetes, Body Mass Index, and High-Density Lipoprotein Cholesterol in a Hispanic-American Population

(2013) Clive R. Pullinger et al.   Metabolic Syndrome and Related Disorders

Comparison of in vivo effects of insulin on SREBP-1c activation and INSIG-1/2 in rat liver and human and rat adipose tissue

(2013) Guenther Boden et al.   Obesity

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

(2012) Young-Ah Moon et al.   Cell Metabolism

The HMGA1-IGF-I/IGFBP System: A Novel Pathway for Modulating Glucose Uptake

(2012) Stefania Iiritano et al.   MOLECULAR ENDOCRINOLOGY

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Hepatoprotective effect of oleuropein in mice: Mechanisms uncovered by gene expression profiling

(2010) Yunjung Kim et al.   Biotechnology Journal

Biological Activities of Phenolic Compounds Present in Virgin Olive Oil

(2010) Sara Cicerale et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oleuropein attenuates hepatic steatosis induced by high-fat diet in mice

(2010) Soyoung Park et al.   JOURNAL OF HEPATOLOGY

Sasa borealis leaves extract improves insulin resistance by modulating inflammatory cytokine secretion in high fat diet-induced obese C57/BL6J mice

(2010) Jung-Hwa Yang et al.   Nutrition Research and Practice

Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1)

(2009) Adriana Bianconcini et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Synthesis, Biological Evaluation, and Molecular Modeling of Oleuropein and Its Semisynthetic Derivatives as Cyclooxygenase Inhibitors

(2009) Antonio Procopio et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-  (PPAR ) and thiazolidinedione-PPAR  agonists

(2008) V Costa et al.   ENDOCRINE-RELATED CANCER