The Antioxidant Procyanidin Reduces Reactive Oxygen Species Signaling in Macrophages and Ameliorates Experimental Colitis in Mice

Fecal Matrix Metalloprotease-9 and Lipocalin-2 as Biomarkers in Detecting Endoscopic Activity in Patients With Inflammatory Bowel Diseases

(2017) Anthony Buisson et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Grape seed-derived procyanidins alleviate gout pain via NLRP3 inflammasome suppression

(2017) Hai-Jiao Liu et al.   Journal of Neuroinflammation

Reactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer Therapy

(2017) Hanna-Riikka Teppo et al.   Oxidative Medicine and Cellular Longevity

Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation induced by zinc oxide nanoparticles in A549 cells

(2017) Xiao Liang et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Anti-inflammatory and anti-apoptotic effects of rosuvastatin by regulation of oxidative stress in a dextran sulfate sodium-induced colitis model

(2017) Seung Kak Shin et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The prognostic value of histology in ulcerative colitis in clinical remission with mesalazine

(2017) Giuseppe Frieri et al.   Therapeutic Advances in Gastroenterology

Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency

(2016) Dror S. Shouval et al.   GASTROENTEROLOGY

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

(2016) Pedro A Ruiz et al.   GUT

Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microglia

(2016) Yang Cai et al.   Journal of Neuroinflammation

Expressions of Matrix Metalloproteinases (MMP-2, MMP-7, and MMP-9) and Their Inhibitors (TIMP-1, TIMP-2) in Inflammatory Bowel Diseases

(2016) Katarzyna Jakubowska et al.   Gastroenterology Research and Practice

Andrographolide ameliorates OVA-induced lung injury in mice by suppressing ROS-mediated NF-κB signaling and NLRP3 inflammasome activation

(2016) Shuang Peng et al.   Oncotarget

Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis

(2015) Prashant Nighot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A new pharmacological effect of levornidazole: Inhibition of NLRP3 inflammasome activation

(2015) Xingqi Wang et al.   BIOCHEMICAL PHARMACOLOGY

A Thermo-Sensitive Delivery Platform for Topical Administration of Inflammatory Bowel Disease Therapies

(2015) Sidhartha R. Sinha et al.   GASTROENTEROLOGY

Epithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-κB activation

(2015) Liren Li et al.   IMMUNOLOGIC RESEARCH

The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases

(2015) Mutlay Sayan et al.   Particle and Fibre Toxicology

Diversity of Intestinal Macrophages in Inflammatory Bowel Diseases

(2015) Anja A. Kühl et al.   Frontiers in Immunology

Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone

(2014) Xue-Feng Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Constitutive expression of MMP9 in intestinal epithelium worsens murine acute colitis and is associated with increased levels of proinflammatory cytokine Kc

(2013) Hongchun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Inflammatory Bowel Disease: Mechanisms, Redox Considerations, and Therapeutic Targets

(2013) Fiorella Biasi et al.   ANTIOXIDANTS & REDOX SIGNALING

Grape seed procyanidin extract reduces the endotoxic effects induced by lipopolysaccharide in rats

(2013) Victor Pallarès et al.   FREE RADICAL BIOLOGY AND MEDICINE

IL-10 modulates DSS-induced colitis through a macrophage–ROS–NO axis

(2013) B Li et al.   Mucosal Immunology

A clinical review of recent findings in the epidemiology of inflammatory bowel disease

(2013) Millie Long et al.   Clinical Epidemiology

Yuwen02f1 suppresses LPS-induced endotoxemia and adjuvant-induced arthritis primarily through blockade of ROS formation, NFkB and MAPK activation

(2012) Chun-Chieh Hsu et al.   BIOCHEMICAL PHARMACOLOGY

An Orally Administered Redox Nanoparticle That Accumulates in the Colonic Mucosa and Reduces Colitis in Mice

(2012) Long Binh Vong et al.   GASTROENTEROLOGY

Colitis-associated cancer: the dark side of inflammatory bowel disease

(2011) S. Danese et al.   GUT

Inflammatory responses of RAW 264.7 macrophages upon exposure to nanoparticles: Role of ROS-NFκB signaling pathway

(2011) Reddy P. Nishanth et al.   Nanotoxicology

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

(2010) Simon A. Hirota et al.   INFLAMMATORY BOWEL DISEASES

Importance of disrupted intestinal barrier in inflammatory bowel diseases

(2010) Saʼad Y. Salim et al.   INFLAMMATORY BOWEL DISEASES

Regulation of adaptive immunity by the NLRP3 inflammasome

(2010) Mingkuan Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

(2009) Pallavi Garg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

NLRP3 (NALP3, Cryopyrin) Facilitates In Vivo Caspase-1 Activation, Necrosis, and HMGB1 Release via Inflammasome-Dependent and -Independent Pathways

(2009) S. B. Willingham et al.   JOURNAL OF IMMUNOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols