Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation induced by zinc oxide nanoparticles in A549 cells

Comparative Analysis of Transcriptional Profile Changes in Larval Zebrafish Exposed to Zinc Oxide Nanoparticles and Zinc Sulfate

(2016) Ryeo-Ok Kim et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Zinc oxide nanoparticles induce renal toxicity through reactive oxygen species

(2016) Lu Xiao et al.   FOOD AND CHEMICAL TOXICOLOGY

Cyto-genotoxicity and oxidative stress induced by zinc oxide nanoparticle in human lymphocyte cells in vitro and Swiss albino male mice in vivo

(2016) Manosij Ghosh et al.   FOOD AND CHEMICAL TOXICOLOGY

Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats

(2016) Zhengwang Cao et al.   International Journal of Nanomedicine

Developmental Toxicity of Zinc Oxide Nanoparticles to Zebrafish (Danio rerio): A Transcriptomic Analysis

(2016) Jin Soo Choi et al.   PLoS One

The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm

(2015) Jeremy A. Hirota et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation

(2015) Gregory M. Orlowski et al.   JOURNAL OF IMMUNOLOGY

The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases

(2015) Mutlay Sayan et al.   Particle and Fibre Toxicology

The complex cascade of cellular events governing inflammasome activation and IL-1β processing in response to inhaled particles

(2015) Virginie Rabolli et al.   Particle and Fibre Toxicology

Sintered Indium-Tin Oxide Particles Induce Pro-Inflammatory Responses In Vitro, in Part through Inflammasome Activation

(2015) Melissa A. Badding et al.   PLoS One

High-temperature calcined fullerene nanowhiskers as well as long needle-like multi-wall carbon nanotubes have abilities to induce NLRP3-mediated IL-1β secretion

(2014) Hongyan Cui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcriptional and posttranscriptional regulation and endocytosis were involved in zinc oxide nanoparticle-induced interleukin-8 overexpression in human bronchial epithelial cells

(2014) Zhen Yan et al.   CELL BIOLOGY AND TOXICOLOGY

Reactive oxygen species mediate IL-8 expression in Down syndrome candidate region-1-overexpressed cells

(2014) Je Won Ko et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation

(2014) Joyce K Thompson et al.   Particle and Fibre Toxicology

Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs

(2014) Paul M Peeters et al.   Particle and Fibre Toxicology

Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review

(2013) Olesja Bondarenko et al.   ARCHIVES OF TOXICOLOGY

Titanium Dioxide Nanoparticles Induced Proinflammation of Primary Cultured Cardiac Myocytes of Rat

(2013) Wei Song et al.   Journal of Nanomaterials

Effect of multi-walled carbon nanotube surface modification on bioactivity in the C57BL/6 mouse model

(2013) Tina M. Sager et al.   Nanotoxicology

Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells

(2013) Jedd M Hillegass et al.   Particle and Fibre Toxicology

Silica induces NLRP3 inflammasome activation in human lung epithelial cells

(2013) Paul M Peeters et al.   Particle and Fibre Toxicology

Association of zinc ion release and oxidative stress induced by intratracheal instillation of ZnO nanoparticles to rat lung

(2012) Hiroko Fukui et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Inflammasome Activators Induce Interleukin-1α Secretion via Distinct Pathways with Differential Requirement for the Protease Function of Caspase-1

(2012) Olaf Groß et al.   IMMUNITY

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

(2012) Jeremy A. Hirota et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

N-acetylcysteine Administration is Associated with Reduced Activation of NF-kB and Preserves Lung Dendritic Cells Function in a Zymosan-Induced Generalized Inflammation Model

(2012) Hong-Wei Wang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Caspase-1 Activation of Interleukin-1β (IL-1β) and IL-18 Is Dispensable for Induction of Experimental Cerebral Malaria

(2011) Maximilian Kordes et al.   INFECTION AND IMMUNITY

Pulmonary toxicity of inhaled nanoscale and fine zinc oxide particles: Mass and surface area as an exposure metric

(2011) Meng Ho et al.   INHALATION TOXICOLOGY

NLRP3/Caspase-1-Independent IL-1  Production Mediates Diesel Exhaust Particle-Induced Pulmonary Inflammation

(2011) S. Provoost et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation

(2011) Etienne Meunier et al.   Nanomedicine-Nanotechnology Biology and Medicine

A Yersinia Effector with Enhanced Inhibitory Activity on the NF-κB Pathway Activates the NLRP3/ASC/Caspase-1 Inflammasome in Macrophages

(2011) Ying Zheng et al.   PLoS Pathogens

Alveolar Epithelial Cell Injury Due to Zinc Oxide Nanoparticle Exposure

(2010) Yong Ho Kim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Phosphorylation of p65 Is Required for Zinc Oxide Nanoparticle–Induced Interleukin 8 Expression in Human Bronchial Epithelial Cells

(2010) Weidong Wu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Sterile inflammatory responses mediated by the NLRP3 inflammasome

(2010) Suzanne L. Cassel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1  and IL-1 

(2010) A. S. Yazdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxicity of zinc oxide nanoparticles to zebrafish embryo: a physicochemical study of toxicity mechanism

(2009) Wei Bai et al.   JOURNAL OF NANOPARTICLE RESEARCH

Copper Oxide Nanoparticles Are Highly Toxic: A Comparison between Metal Oxide Nanoparticles and Carbon Nanotubes

(2008) Hanna L. Karlsson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Toxicity of nano- and micro-sized ZnO particles in human lung epithelial cells

(2008) Weisheng Lin et al.   JOURNAL OF NANOPARTICLE RESEARCH

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE