Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis

Constitutive expression of MMP9 in intestinal epithelium worsens murine acute colitis and is associated with increased levels of proinflammatory cytokine Kc

(2013) Hongchun Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

TNFR2 Activates MLCK-Dependent Tight Junction Dysregulation to Cause Apoptosis-Mediated Barrier Loss and Experimental Colitis

(2013) Liping Su et al.   GASTROENTEROLOGY

Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis

(2013) Prashant Nighot et al.   INFLAMMATORY BOWEL DISEASES

MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation and Tissue Injury

(2013) Chenzhang Shi et al.   PLoS One

The Impact of Matrix Metalloproteinases and Their Tissue Inhibitors in Inflammatory Bowel Diseases

(2012) Gábor Lakatos et al.   DIGESTIVE DISEASES

Myosin Light Chain Kinase Inhibitor Inhibits Dextran Sulfate Sodium-Induced Colitis in Mice

(2012) Xiaochang Liu et al.   DIGESTIVE DISEASES AND SCIENCES

Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation

(2012) Shila Gilbert et al.   EMBO Molecular Medicine

Fecal MMP-9

(2012) Anita Annaházi et al.   INFLAMMATORY BOWEL DISEASES

Mechanism of Interleukin-1β Induced-Increase in Mouse Intestinal Permeability In Vivo

(2012) Rana Al-Sadi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Serum MMPs 7–9 and their inhibitors during glucocorticoid and anti-TNF-α therapy in pediatric inflammatory bowel disease

(2012) Laura Mäkitalo et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Chloride channel ClC-2 modulates tight junction barrier function via intracellular trafficking of occludin

(2011) Prashant K. Nighot et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Occludin regulates macromolecule flux across the intestinal epithelial tight junction barrier

(2011) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9

(2011) Ruifen Xu et al.   BRAIN RESEARCH

Correlation of MMP-3 and MMP-9 with Crohn’s Disease Activity in Children

(2011) Anna Kofla-Dlubacz et al.   DIGESTIVE DISEASES AND SCIENCES

Matrix Metalloproteinase-9 Inhibition Reduces Inflammation and Improves Motility in Murine Models of Postoperative Ileus

(2011) Beverley A. Moore et al.   GASTROENTEROLOGY

MicroRNA Regulation of Intestinal Epithelial Tight Junction Permeability

(2011) Dongmei Ye et al.   GASTROENTEROLOGY

Suppression of MMP-9 Expression in Brain Microvascular Endothelial Cells (BMVEC) Using a Gold Nanorod (GNR)-siRNA Nanoplex

(2011) Supriya D. Mahajan et al.   IMMUNOLOGICAL INVESTIGATIONS

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism

(2011) Fang Yan et al.   JOURNAL OF CLINICAL INVESTIGATION

The Behavior of Matrix Metalloproteinase-9 in Lymphocytic Colitis, Collagenous Colitis and Ulcerative Colitis

(2011) Gábor Lakatos et al.   PATHOLOGY & ONCOLOGY RESEARCH

CXCR4 Antagonist AMD3100 Modulates Claudin Expression and Intestinal Barrier Function in Experimental Colitis

(2011) Xian-Ming Xia et al.   PLoS One

Epithelial Myosin Light Chain Kinase Activation Induces Mucosal Interleukin-13 Expression to Alter Tight Junction Ion Selectivity

(2010) Christopher R. Weber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

(2010) Alexander T Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

(2009) Pallavi Garg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis

(2009) Rudolf Mennigen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

TGF-β1 induced MMP-9 expression in HNSCC cell lines via Smad/MLCK pathway

(2008) Sariya Nuchanardpanit Sinpitaksakul et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis

(2008) Liping Su et al.   GASTROENTEROLOGY

Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse

(2008) M C Arrieta et al.   GUT

Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease

(2008) Michael A. Manfredi et al.   INFLAMMATORY BOWEL DISEASES

Changes in the expression of claudins in active ulcerative colitis

(2008) Tadayuki Oshima et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

(2008) Wenlan Liu et al.   JOURNAL OF NEUROCHEMISTRY

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

(2008) Christopher R Weber et al.   LABORATORY INVESTIGATION