The Wnt Signaling Pathway and Related Therapeutic Drugs in Autism Spectrum Disorder

Wnt and GSK3 Signaling Pathways in Bipolar Disorder: Clinical and Therapeutic Implications

(2017) Ather Muneer   Clinical Psychopharmacology and Neuroscience

Generating Cellular Diversity and Spatial Form: Wnt Signaling and the Evolution of Multicellular Animals

(2016) Kyle M. Loh et al.   DEVELOPMENTAL CELL

Genetic alterations of δ-catenin/NPRAP/Neurojungin (CTNND2): functional implications in complex human diseases

(2016) Qun Lu et al.   HUMAN GENETICS

Deletion of CTNNB1 in inhibitory circuitry contributes to autism-associated behavioral defects

(2016) Fengping Dong et al.   HUMAN MOLECULAR GENETICS

Wnt signaling networks in autism spectrum disorder and intellectual disability

(2016) Vickie Kwan et al.   Journal of Neurodevelopmental Disorders

Shank Modulates Postsynaptic Wnt Signaling to Regulate Synaptic Development

(2016) K. P. Harris et al.   JOURNAL OF NEUROSCIENCE

Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling

(2016) Omer Durak et al.   NATURE NEUROSCIENCE

Autism and Cancer Share Risk Genes, Pathways, and Drug Targets

(2016) Jacqueline N. Crawley et al.   TRENDS IN GENETICS

Synaptic Wnt/GSK3βSignaling Hub in Autism

(2016) Mario O. Caracci et al.   NEURAL PLASTICITY

The antidepressant roles of Wnt2 and Wnt3 in stress-induced depression-like behaviors

(2016) W-J Zhou et al.   Translational Psychiatry

Use of Clozapine for Borderline Personality Disorder: A Case Report

(2016) Badii Amamou et al.   Clinical Psychopharmacology and Neuroscience

First glimpses of the neurobiology of autism spectrum disorder

(2015) Stephan J Sanders   CURRENT OPINION IN GENETICS & DEVELOPMENT

Loss of δ-catenin function in severe autism

(2015) Tychele N. Turner et al.   NATURE

Mutations and Modeling of the Chromatin Remodeler CHD8 Define an Emerging Autism Etiology

(2015) Rebecca A. Barnard et al.   Frontiers in Neuroscience

Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities

(2014) J L Mohn et al.   MOLECULAR PSYCHIATRY

Can we safely target the WNT pathway?

(2014) Michael Kahn   NATURE REVIEWS DRUG DISCOVERY

An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control

(2014) H. Clevers et al.   SCIENCE

A de novo convergence of autism genetics and molecular neuroscience

(2014) Niklas Krumm et al.   TRENDS IN NEUROSCIENCES

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

(2014) Claire S. Leblond et al.   PLoS Genetics

Disruption of the non-canonical Wnt gene PRICKLE2 leads to autism-like behaviors with evidence for hippocampal synaptic dysfunction

(2013) L P Sowers et al.   MOLECULAR PSYCHIATRY

AKT activation by N-cadherin regulates beta-catenin signaling and neuronal differentiation during cortical development

(2013) Jianing Zhang et al.   Neural Development

A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation

(2013) P-M Martin et al.   Translational Psychiatry

Brain region differences in regulation of Akt and GSK3 by chronic stimulant administration in mice

(2012) Marjelo A. Mines et al.   CELLULAR SIGNALLING

Down's-syndrome-related kinase Dyrk1A modulates the p120-catenin-Kaiso trajectory of the Wnt signaling pathway

(2012) J. Y. Hong et al.   JOURNAL OF CELL SCIENCE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males

(2011) Ren-Hua Chung et al.   Molecular Autism

Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16

(2011) J M Launay et al.   Translational Psychiatry

Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members

(2010) J. Y. Hong et al.   JOURNAL OF CELL SCIENCE

Novel de novo SHANK3 mutation in autistic patients

(2008) Julie Gauthier et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS