Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities

A de novo convergence of autism genetics and molecular neuroscience

(2014) Niklas Krumm et al.   TRENDS IN NEUROSCIENCES

Wnt signaling in the nervous system and in Alzheimer's disease

(2014) N. C. Inestrosa et al.   Journal of Molecular Cell Biology

Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism

(2013) A. Jeremy Willsey et al.   CELL

Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism

(2013) Neelroop N. Parikshak et al.   CELL

Loss of Dickkopf-1 Restores Neurogenesis in Old Age and Counteracts Cognitive Decline

(2013) Désirée R.M. Seib et al.   Cell Stem Cell

Canonical Wnt Signaling is Necessary for Object Recognition Memory Consolidation

(2013) A. M. Fortress et al.   JOURNAL OF NEUROSCIENCE

WNT signaling in neuronal maturation and synaptogenesis

(2013) Silvana B. Rosso et al.   Frontiers in Cellular Neuroscience

A rare WNT1 missense variant overrepresented in ASD leads to increased Wnt signal pathway activation

(2013) P-M Martin et al.   Translational Psychiatry

Wnt Signaling Regulates Acetylcholine Receptor Translocation and Synaptic Plasticity in the Adult Nervous System

(2012) Michael Jensen et al.   CELL

Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries

(2012) Michael E. Talkowski et al.   CELL

WNTs in synapse formation and neuronal circuitry

(2012) Mikyoung Park et al.   EMBO JOURNAL

A Role for WNT/β-Catenin Signaling in the Neural Mechanisms of Behavior

(2012) Kimberly A. Maguschak et al.   Journal of Neuroimmune Pharmacology

Patterns and rates of exonic de novo mutations in autism spectrum disorders

(2012) Benjamin M. Neale et al.   NATURE

De Novo Gene Disruptions in Children on the Autistic Spectrum

(2012) Ivan Iossifov et al.   NEURON

Diagnostic Exome Sequencing in Persons with Severe Intellectual Disability

(2012) Joep de Ligt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

(2012) B. J. O'Roak et al.   SCIENCE

Wnt Signaling in the Vertebrate Central Nervous System: From Axon Guidance to Synaptic Function

(2012) P. C. Salinas   Cold Spring Harbor Perspectives in Biology

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

The  -Catenin Destruction Complex

(2012) J. L. Stamos et al.   Cold Spring Harbor Perspectives in Biology

Age-Dependent Brain Gene Expression and Copy Number Anomalies in Autism Suggest Distinct Pathological Processes at Young Versus Mature Ages

(2012) Maggie L. Chow et al.   PLoS Genetics

Cadherin-catenin adhesion complexes at the synapse

(2011) G Stefano Brigidi et al.   CURRENT OPINION IN NEUROBIOLOGY

Wnt Signaling in Amygdala-Dependent Learning and Memory

(2011) K. A. Maguschak et al.   JOURNAL OF NEUROSCIENCE

Regulation of NMDA-Receptor Synaptic Transmission by Wnt Signaling

(2011) W. Cerpa et al.   JOURNAL OF NEUROSCIENCE

Ca2+permeable AMPA receptors switch allegiances: mechanisms and consequences

(2011) Siqiong June Liu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Adenomatous polyposis coli heterozygous knockout mice display hypoactivity and age-dependent working memory deficits

(2011) Hisatsugu Koshimizu et al.   Frontiers in Behavioral Neuroscience

Genome-wide identification of new Wnt/β-catenin target genes in the human genome using CART method

(2010) Christian Hödar et al.   BMC GENOMICS

Motor and cognitive stereotypies in the BTBR T+tf/J mouse model of autism

(2010) B. L. Pearson et al.   GENES BRAIN AND BEHAVIOR

Canonical Wnt3a Modulates Intracellular Calcium and Enhances Excitatory Neurotransmission in Hippocampal Neurons

(2010) Miguel E. Avila et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Postsynaptic Adenomatous Polyposis Coli (APC) Multiprotein Complex Is Required for Localizing Neuroligin and Neurexin to Neuronal Nicotinic Synapses in Vivo

(2010) M. M. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Fragile X Mental Retardation Protein Regulates Proliferation and Differentiation of Adult Neural Stem/Progenitor Cells

(2010) Yuping Luo et al.   PLoS Genetics

Cytoplasmic Polyadenylation Element-Binding Protein Regulates Neurotrophin-3-Dependent  -Catenin mRNA Translation in Developing Hippocampal Neurons

(2009) M. Kundel et al.   JOURNAL OF NEUROSCIENCE

Adenomatous polyposis coli is required for early events in the normal growth and differentiation of the developing cerebral cortex

(2009) Uladzislau Ivaniutsin et al.   Neural Development

The Adenomatous Polyposis Coli Protein Is an Essential Regulator of Radial Glial Polarity and Construction of the Cerebral Cortex

(2009) Yukako Yokota et al.   NEURON

Activation of calcium/calmodulin-dependent protein kinase IIα in the striatum by the heteromeric D1-D2 dopamine receptor complex

(2009) J. Ng et al.   NEUROSCIENCE

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

Adenomatous polyposis coli plays a key role, in vivo, in coordinating assembly of the neuronal nicotinic postsynaptic complex

(2008) Madelaine M. Rosenberg et al.   MOLECULAR AND CELLULAR NEUROSCIENCE