An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
Authors
Keywords
-
Journal
SCIENCE
Volume 346, Issue 6205, Pages 1248012-1248012
Publisher
American Association for the Advancement of Science (AAAS)
Online
2014-10-03
DOI
10.1126/science.1248012
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts
- (2014) Z. Kabiri et al. DEVELOPMENT
- In situ identification of bipotent stem cells in the mammary gland
- (2014) Anne C. Rios et al. NATURE
- Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging
- (2014) Laila Ritsma et al. NATURE
- In Vivo Clonal Analysis Reveals Lineage-Restricted Progenitor Characteristics in Mammalian Kidney Development, Maintenance, and Regeneration
- (2014) Yuval Rinkevich et al. Cell Reports
- Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6
- (2014) Jennifer L Stamos et al. eLife
- Wnt Secretion from Epithelial Cells and Subepithelial Myofibroblasts Is Not Required in the Mouse Intestinal Stem Cell Niche In Vivo
- (2014) Adrianna K. San Roman et al. Stem Cell Reports
- Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells
- (2013) T. A. Jan et al. DEVELOPMENT
- Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
- (2013) Meritxell Huch et al. EMBO JOURNAL
- Intestinal label-retaining cells are secretory precursors expressing Lgr5
- (2013) Simon J. A. Buczacki et al. NATURE
- In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
- (2013) Meritxell Huch et al. NATURE
- Spatial organization within a niche as a determinant of stem-cell fate
- (2013) Panteleimon Rompolas et al. NATURE
- Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche
- (2013) Andrea Flesken-Nikitin et al. NATURE
- RNAi screens in mice identify physiological regulators of oncogenic growth
- (2013) Slobodan Beronja et al. NATURE
- Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury
- (2013) Norifumi Takeda et al. PLoS One
- Lineage tracing with Axin2 reveals distinct developmental and adult populations of Wnt/ -catenin-responsive neural stem cells
- (2013) A. N. Bowman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
- (2013) S. J. Habib et al. SCIENCE
- Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications
- (2013) T. Sato et al. SCIENCE
- The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution
- (2013) J. F. Ryan et al. SCIENCE
- Interfollicular Epidermal Stem Cells Self-Renew via Autocrine Wnt Signaling
- (2013) X. Lim et al. SCIENCE
- Lgr5-EGFP Marks Taste Bud Stem/Progenitor Cells in Posterior Tongue
- (2013) Karen K. Yee et al. STEM CELLS
- Lgr5+ Gastric Stem Cells Divide Symmetrically to Effect Epithelial Homeostasis in the Pylorus
- (2013) Marc Leushacke et al. Cell Reports
- Lgr5-Expressing Cells Are Sufficient and Necessary for Postnatal Mammary Gland Organogenesis
- (2013) Vicki Plaks et al. Cell Reports
- The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor
- (2012) Anne E. Powell et al. CELL
- Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland
- (2012) Renée van Amerongen et al. Cell Stem Cell
- A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities
- (2012) Rani Najdi et al. DIFFERENTIATION
- The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers
- (2012) Javier Muñoz et al. EMBO JOURNAL
- Redundant Sources of Wnt Regulate Intestinal Stem Cells and Promote Formation of Paneth Cells
- (2012) Henner F. Farin et al. GASTROENTEROLOGY
- Developmental stage-specific contribution of LGR5+ cells to basal and luminal epithelial lineages in the postnatal mammary gland
- (2012) Karin E de Visser et al. JOURNAL OF PATHOLOGY
- A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal
- (2012) J. H. van Es et al. MOLECULAR AND CELLULAR BIOLOGY
- ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
- (2012) Huai-Xiang Hao et al. NATURE
- Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
- (2012) Bon-Kyoung Koo et al. NATURE
- Active Wnt proteins are secreted on exosomes
- (2012) Julia Christina Gross et al. NATURE CELL BIOLOGY
- Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
- (2012) Johan H. van Es et al. NATURE CELL BIOLOGY
- Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
- (2012) Vivian W. Y. Wong et al. NATURE CELL BIOLOGY
- Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell
- (2012) Shiro Yui et al. NATURE MEDICINE
- Wnt/ -Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells
- (2012) K. Hoffmeyer et al. SCIENCE
- Structural Basis of Wnt Recognition by Frizzled
- (2012) C. Y. Janda et al. SCIENCE
- Lgr5+ve Stem/Progenitor Cells Contribute to Nephron Formation during Kidney Development
- (2012) Nick Barker et al. Cell Reports
- The R-spondin protein family
- (2012) Wim BM de Lau et al. GENOME BIOLOGY
- Universal patterns of stem cell fate in cycling adult tissues
- (2011) A. M. Klein et al. DEVELOPMENT
- Drosophila Stem Cell Niches: A Decade of Discovery Suggests a Unified View of Stem Cell Regulation
- (2011) Vicki P. Losick et al. DEVELOPMENTAL CELL
- Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes
- (2011) Arnout G Schepers et al. EMBO JOURNAL
- LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling
- (2011) Andrei Glinka et al. EMBO REPORTS
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
- (2011) Hua Tian et al. NATURE
- Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
- (2011) Wim de Lau et al. NATURE
- Distinct stem cells contribute to mammary gland development and maintenance
- (2011) Alexandra Van Keymeulen et al. NATURE
- Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
- (2011) Kunyoo Shin et al. NATURE
- Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells
- (2011) Derk ten Berge et al. NATURE CELL BIOLOGY
- Single-molecule transcript counting of stem-cell markers in the mouse intestine
- (2011) Shalev Itzkovitz et al. NATURE CELL BIOLOGY
- R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling
- (2011) K. S. Carmon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations
- (2011) K. S. Yan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interconversion Between Intestinal Stem Cell Populations in Distinct Niches
- (2011) N. Takeda et al. SCIENCE
- The ground state of pluripotency
- (2010) Jason Wray et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells
- (2010) Hugo J. Snippert et al. CELL
- Wnt Proteins Are Self-Renewal Factors for Mammary Stem Cells and Promote Their Long-Term Expansion in Culture
- (2010) Yi Arial Zeng et al. Cell Stem Cell
- Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro
- (2010) Nick Barker et al. Cell Stem Cell
- Brachyury establishes the embryonic mesodermal progenitor niche
- (2010) B. L. Martin et al. GENES & DEVELOPMENT
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
- (2010) Toshiro Sato et al. NATURE
- Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells
- (2010) R. K. Montgomery et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functional Hierarchy and Reversibility Within the Murine Spermatogenic Stem Cell Compartment
- (2010) T. Nakagawa et al. SCIENCE
- Intestinal Stem Cell Replacement Follows a Pattern of Neutral Drift
- (2010) C. Lopez-Garcia et al. SCIENCE
- A Transient Niche Regulates the Specification of Drosophila Intestinal Stem Cells
- (2010) D. Mathur et al. SCIENCE
- Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless
- (2009) Ceren Korkut et al. CELL
- Wnt Signaling and the Polarity of the Primary Body Axis
- (2009) Christian P. Petersen et al. CELL
- Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis
- (2009) Kim B. Jensen et al. Cell Stem Cell
- Towards an integrated view of Wnt signaling in development
- (2009) R. van Amerongen et al. DEVELOPMENT
- Multiple Wnts are involved in Hydra organizer formation and regeneration
- (2009) Tobias Lengfeld et al. DEVELOPMENTAL BIOLOGY
- Apoptotic Cells Provide an Unexpected Source of Wnt3 Signaling to Drive Hydra Head Regeneration
- (2009) Simona Chera et al. DEVELOPMENTAL CELL
- Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
- (2009) Toshiro Sato et al. NATURE
- Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia
- (2009) Hoang Nguyen et al. NATURE GENETICS
- The Wnt Receptor, Lrp5, Is Expressed by Mouse Mammary Stem Cells and Is Required to Maintain the Basal Lineage
- (2009) Nisha M. Badders et al. PLoS One
- R-Spondin Family Members Regulate the Wnt Pathway by a Common Mechanism
- (2008) Kyung-Ah Kim et al. MOLECULAR BIOLOGY OF THE CELL
- Centrosome misorientation reduces stem cell division during ageing
- (2008) Jun Cheng et al. NATURE
- The Trichoplax genome and the nature of placozoans
- (2008) Mansi Srivastava et al. NATURE
- The ground state of embryonic stem cell self-renewal
- (2008) Qi-Long Ying et al. NATURE
- Lgr5 marks cycling, yet long-lived, hair follicle stem cells
- (2008) Viljar Jaks et al. NATURE GENETICS
- Bmi1 is expressed in vivo in intestinal stem cells
- (2008) Eugenio Sangiorgi et al. NATURE GENETICS
- Generation of mTert-GFP mice as a model to identify and study tissue progenitor cells
- (2008) D. T. Breault et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Catenin Defines Head Versus Tail Identity During Planarian Regeneration and Homeostasis
- (2007) K. A. Gurley et al. SCIENCE
- Smed- catenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration
- (2007) C. P. Petersen et al. SCIENCE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started