The Regulation of Inflammation by Innate and Adaptive Lymphocytes

Lessons learned from twins in autoimmune and chronic inflammatory diseases

(2017) Elena Generali et al.   JOURNAL OF AUTOIMMUNITY

Phagocytosis imprints heterogeneity in tissue-resident macrophages

(2017) Noelia A-Gonzalez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota

(2017) Qing Zhao et al.   JOURNAL OF IMMUNOLOGY

IL-15 supports the generation of protective lung-resident memory CD4 T cells

(2017) T M Strutt et al.   Mucosal Immunology

Helminth-induced alterations of the gut microbiota exacerbate bacterial colitis

(2017) C Su et al.   Mucosal Immunology

Lipocalin-2: A Master Mediator of Intestinal and Metabolic Inflammation

(2017) Alexander R. Moschen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The microbiota protects against respiratory infection via GM-CSF signaling

(2017) Rebecca L. Brown et al.   Nature Communications

Distinct Microbial Communities Trigger Colitis Development upon Intestinal Barrier Damage via Innate or Adaptive Immune Cells

(2017) Urmi Roy et al.   Cell Reports

Host and Environmental Factors Influencing Individual Human Cytokine Responses

(2016) Rob ter Horst et al.   CELL

Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity

(2016) Melanie Schirmer et al.   CELL

A Long Noncoding RNA lincRNA-EPS Acts as a Transcriptional Brake to Restrain Inflammation

(2016) Maninjay K. Atianand et al.   CELL

Inflammasome Complexes: Emerging Mechanisms and Effector Functions

(2016) Vijay A.K. Rathinam et al.   CELL

Mass Cytometry: Single Cells, Many Features

(2016) Matthew H. Spitzer et al.   CELL

Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response

(2016) Helen Weavers et al.   CELL

A Stringent Systems Approach Uncovers Gene-Specific Mechanisms Regulating Inflammation

(2016) Ann-Jay Tong et al.   CELL

In VitroExperimental Model of Trained Innate Immunity in Human Primary Monocytes

(2016) Siroon Bekkering et al.   Clinical and Vaccine Immunology

Defensins, lectins, mucins, and secretory immunoglobulin A: microbe-binding biomolecules that contribute to mucosal immunity in the human gut

(2016) Phoom Chairatana et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication

(2016) Elena Carnero et al.   EMBO REPORTS

Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure

(2016) Sheryl Coutermarsh-Ott et al.   JOURNAL OF GENERAL VIROLOGY

Direct IL-6 Signals Maximize Protective Secondary CD4 T Cell Responses against Influenza

(2016) Tara M. Strutt et al.   JOURNAL OF IMMUNOLOGY

Defensins at the Mucosal Surface: Latest Insights into Defensin-Virus Interactions

(2016) Sarah S. Wilson et al.   JOURNAL OF VIROLOGY

NK cells and type 1 innate lymphoid cells: partners in host defense

(2016) Hergen Spits et al.   NATURE IMMUNOLOGY

The development and maintenance of resident macrophages

(2016) Elisa Gomez Perdiguero et al.   NATURE IMMUNOLOGY

Innate cell communication kick-starts pathogen-specific immunity

(2016) Amariliz Rivera et al.   NATURE IMMUNOLOGY

PGE2 induced in and released by dying cells functions as an inhibitory DAMP

(2016) Sho Hangai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Memory CD8 + T Cells: Innate-Like Sensors and Orchestrators of Protection

(2016) Grégoire Lauvau et al.   TRENDS IN IMMUNOLOGY

Triggering Intracellular Receptors for Vaccine Adjuvantation

(2016) Alice Gutjahr et al.   TRENDS IN IMMUNOLOGY

Morning vaccination enhances antibody response over afternoon vaccination: A cluster-randomised trial

(2016) Joanna E. Long et al.   VACCINE

Mitochondrial H2O2 in Lung Antigen-Presenting Cells Blocks NF-κB Activation to Prevent Unwarranted Immune Activation

(2016) Anupriya Khare et al.   Cell Reports

T-Cell Immunity to Influenza in Older Adults: A Pathophysiological Framework for Development of More Effective Vaccines

(2016) Janet E. McElhaney et al.   Frontiers in Immunology

Heterosubtypic T-Cell Immunity to Influenza in Humans: Challenges for Universal T-Cell Influenza Vaccines

(2016) Saranya Sridhar   Frontiers in Immunology

A Gammaherpesvirus Noncoding RNA Is Essential for Hematogenous Dissemination and Establishment of Peripheral Latency

(2016) Emily R. Feldman et al.   mSphere

Natural Killer Cell Memory

(2015) Timothy E. O’Sullivan et al.   IMMUNITY

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

Strategically Localized Dendritic Cells Promote Rapid T Cell Responses to Lymph-Borne Particulate Antigens

(2015) Michael Y. Gerner et al.   IMMUNITY

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Lipocalin-2 exacerbates psoriasiform skin inflammation by augmenting T-helper 17 response

(2015) Carren S. Hau et al.   JOURNAL OF DERMATOLOGY

Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2

(2015) Stefan A. Schattgen et al.   JOURNAL OF IMMUNOLOGY

Airway-Resident Memory CD8 T Cells Provide Antigen-Specific Protection against Respiratory Virus Challenge through Rapid IFN-γ Production

(2015) Sean R. McMaster et al.   JOURNAL OF IMMUNOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

The prevention and eradication of smallpox: a commentary on Sloane (1755) 'An account of inoculation'

(2015) R. A. Weiss et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Vaccination and heterologous immunity: educating the immune system

(2015) Anna Gil et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Inflammasome control of viral infection

(2015) Christopher Lupfer et al.   Current Opinion in Virology

CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue

(2015) Gabrielle Stack et al.   PLoS Pathogens

lncRNAs regulate the innate immune response to viral infection

(2015) Jing Ouyang et al.   Wiley Interdisciplinary Reviews-RNA

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

(2015) Abhishek D. Garg et al.   Frontiers in Immunology

Heterologous immunity between viruses

(2015) Raymond M. Welsh et al.   IMMUNOLOGICAL REVIEWS

Memory-T-Cell-Derived Interferon-γ Instructs Potent Innate Cell Activation for Protective Immunity

(2014) Saïdi M’Homa Soudja et al.   IMMUNITY

Circadian Clock Proteins and Immunity

(2014) Anne M. Curtis et al.   IMMUNITY

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

tTregs, pTregs, and iTregs: similarities and differences

(2014) Ethan M. Shevach et al.   IMMUNOLOGICAL REVIEWS

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

mTOR- and HIF-1 -mediated aerobic glycolysis as metabolic basis for trained immunity

(2014) S.-C. Cheng et al.   SCIENCE

Immunologic strategies for HIV-1 remission and eradication

(2014) D. H. Barouch et al.   SCIENCE

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Long non-coding RNAs and control of gene expression in the immune system

(2014) Maninjay K. Atianand et al.   TRENDS IN MOLECULAR MEDICINE

How advances in immunology provide insight into improving vaccine efficacy

(2014) Mark K. Slifka et al.   VACCINE

Antigens for CD4 and CD8 T Cells in Tuberculosis

(2014) C. S. Lindestam Arlehamn et al.   Cold Spring Harbor Perspectives in Medicine

Persistence of LPS-Induced Lung Inflammation in Surfactant Protein-C–Deficient Mice

(2013) Stephan W. Glasser et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting

(2013) Miriam Merad et al.   Annual Review of Immunology

A Systems Analysis Identifies a Feedforward Inflammatory Circuit Leading to Lethal Influenza Infection

(2013) Marlène Brandes et al.   CELL

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

Mechanisms of NOD-like Receptor-Associated Inflammasome Activation

(2013) Haitao Wen et al.   IMMUNITY

Dendritic-Cell-Based Therapeutic Cancer Vaccines

(2013) Karolina Palucka et al.   IMMUNITY

The role of lung dendritic cell subsets in immunity to respiratory viruses

(2013) Katrijn Neyt et al.   IMMUNOLOGICAL REVIEWS

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Influenza A Exacerbates Staphylococcus aureus Pneumonia by Attenuating IL-1  Production in Mice

(2013) K. M. Robinson et al.   JOURNAL OF IMMUNOLOGY

Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

(2013) M Guilliams et al.   Mucosal Immunology

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

(2013) William R Heath et al.   NATURE IMMUNOLOGY

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Unsolved Mysteries in NLR Biology

(2013) Christopher Lupfer et al.   Frontiers in Immunology

Pulmonary surfactant protein A and surfactant lipids upregulate IRAK-M, a negative regulator of TLR-mediated inflammation in human macrophages

(2012) Huy A. Nguyen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

Recognition of Bacteria by Inflammasomes

(2012) Jakob von Moltke et al.   Annual Review of Immunology

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms

(2012) K. Kai McKinstry et al.   JOURNAL OF CLINICAL INVESTIGATION

The origins, function, and regulation of T follicular helper cells

(2012) Cindy S. Ma et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiple Redundant Effector Mechanisms of CD8+ T Cells Protect against Influenza Infection

(2012) H. Hamada et al.   JOURNAL OF IMMUNOLOGY

Blockade of IL-10 Signaling during Bacillus Calmette-Guerin Vaccination Enhances and Sustains Th1, Th17, and Innate Lymphoid IFN-  and IL-17 Responses and Increases Protection to Mycobacterium tuberculosis Infection

(2012) J. M. Pitt et al.   JOURNAL OF IMMUNOLOGY

Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors

(2012) T. M. Strutt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

(2012) J. Kleinnijenhuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antiinflammatory Role of MUC1 Mucin during Infection with NontypeableHaemophilus influenzae

(2011) Yoshiyuki Kyo et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

The inflammasome: an integrated view

(2011) Olaf Gross et al.   IMMUNOLOGICAL REVIEWS

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

(2011) Kathrin Kastenmüller et al.   JOURNAL OF CLINICAL INVESTIGATION

Memory CD4 T Cells That Express CXCR5 Provide Accelerated Help to B Cells

(2011) M. K. L. MacLeod et al.   JOURNAL OF IMMUNOLOGY

Rapid Reactivation of Extralymphoid CD4 T Cells during Secondary Infection

(2011) Timothy J. Chapman et al.   PLoS One

Airway immune homeostasis and implications for influenza-induced inflammation

(2011) Robert J Snelgrove et al.   TRENDS IN IMMUNOLOGY

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Toll-like Receptor 2 Signaling in CD4+ T Lymphocytes Promotes T Helper 17 Responses and Regulates the Pathogenesis of Autoimmune Disease

(2010) Joseph M. Reynolds et al.   IMMUNITY

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

Regulation of CD4+ T-cell contraction during pathogen challenge

(2010) K. Kai McKinstry et al.   IMMUNOLOGICAL REVIEWS

IL-10 production differentially influences the magnitude, quality, and protective capacity of Th1 responses depending on the vaccine platform

(2010) Patricia A. Darrah et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Seasonal FluMist Vaccination Induces Cross-Reactive T Cell Immunity against H1N1 (2009) Influenza and Secondary Bacterial Infections

(2010) K. Sun et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Granulocyte-Macrophage Colony-Stimulating Factor Is the Major CD8+ T Cell-Derived Licensing Factor for Dendritic Cell Activation

(2010) L. Min et al.   JOURNAL OF IMMUNOLOGY

Memory CD4 T Cells Direct Protective Responses to Influenza Virus in the Lungs through Helper-Independent Mechanisms

(2010) J. R. Teijaro et al.   JOURNAL OF VIROLOGY

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+ T cell responses to influenza

(2010) André Ballesteros-Tato et al.   NATURE IMMUNOLOGY

Critical role for the chemokine receptor CXCR6 in NK cell–mediated antigen-specific memory of haptens and viruses

(2010) Silke Paust et al.   NATURE IMMUNOLOGY

Memory CD4+ T cells induce innate responses independently of pathogen

(2010) Tara M Strutt et al.   NATURE MEDICINE

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

Conduits Mediate Transport of Low-Molecular-Weight Antigen to Lymph Node Follicles

(2009) Ramon Roozendaal et al.   IMMUNITY

Cutting Edge: Stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity

(2009) B. Moltedo et al.   JOURNAL OF IMMUNOLOGY

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Adaptive immune features of natural killer cells

(2009) Joseph C. Sun et al.   NATURE

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

(2009) Tri Giang Phan et al.   NATURE IMMUNOLOGY

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses

(2009) I. Amit et al.   SCIENCE

Immune homeostasis in the respiratory tract and its impact on heterologous infection

(2009) Erika Wissinger et al.   SEMINARS IN IMMUNOLOGY

Regulation of Hierarchical Clustering and Activation of Innate Immune Cells by Dendritic Cells

(2008) Suk-Jo Kang et al.   IMMUNITY

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

(2008) Arnaud Didierlaurent et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clearance of influenza virus from the lung depends on migratory langerin+CD11b−but not plasmacytoid dendritic cells

(2008) Corine H. GeurtsvanKessel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Predominant Role of Bacterial Pneumonia as a Cause of Death in Pandemic Influenza: Implications for Pandemic Influenza Preparedness

(2008) David M. Morens et al.   JOURNAL OF INFECTIOUS DISEASES

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

(2008) Li Wen et al.   NATURE

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE

INTERFEROME: the database of interferon regulated genes

(2008) Shamith A. Samarajiwa et al.   NUCLEIC ACIDS RESEARCH

MUC1 Mucin Is a Negative Regulator of Toll-Like Receptor Signaling

(2007) Keiko Ueno et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY