Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

Cutting Edge: Innate Immune Response Triggered by Influenza A Virus Is Negatively Regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-Dependent Pathway

(2014) J. Pothlichet et al.   JOURNAL OF IMMUNOLOGY

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

Lung Dendritic Cells in Respiratory Viral Infection and Asthma: From Protection to Immunopathology

(2012) Bart N. Lambrecht et al.   Annual Review of Immunology

Viral infection triggers rapid differentiation of human blood monocytes into dendritic cells

(2012) W. Hou et al.   BLOOD

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

(2012) L. F. Poulin et al.   BLOOD

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion

(2012) Saïdi M'Homa Soudja et al.   IMMUNITY

Fungi Subvert Vaccine T Cell Priming at the Respiratory Mucosa by Preventing Chemokine-Induced Influx of Inflammatory Monocytes

(2012) Marcel Wüthrich et al.   IMMUNITY

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

(2012) Julie Helft et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Zbtb46expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

(2012) Ansuman T. Satpathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state

(2012) Matthew M. Meredith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage

(2012) Matthew M. Meredith et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD64 Expression Distinguishes Monocyte-Derived and Conventional Dendritic Cells and Reveals Their Distinct Role during Intramuscular Immunization

(2012) C. Langlet et al.   JOURNAL OF IMMUNOLOGY

Rapid Differentiation of Monocytes into Type I IFN-Producing Myeloid Dendritic Cells as an Antiviral Strategy against Influenza Virus Infection

(2012) W. Cao et al.   JOURNAL OF IMMUNOLOGY

Functional Interferon System Is Required for Clearance of Lassa Virus

(2012) N. E. Yun et al.   JOURNAL OF VIROLOGY

TSLP promotes influenza-specific CD8+ T-cell responses by augmenting local inflammatory dendritic cell function

(2012) K Yadava et al.   Mucosal Immunology

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection

(2012) Jonathan Maelfait et al.   PLoS Pathogens

Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation

(2012) Annabell Bachem et al.   Frontiers in Immunology

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection

(2011) Katrin D. Mayer-Barber et al.   IMMUNITY

Dendritic Cell and Macrophage Heterogeneity In Vivo

(2011) Daigo Hashimoto et al.   IMMUNITY

Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza

(2011) Wilbur H. Chen et al.   IMMUNOLOGY LETTERS

Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice

(2011) Heidi A. Schreiber et al.   JOURNAL OF CLINICAL INVESTIGATION

CD103+pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen

(2011) A. Nicole Desch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lung CD103+ Dendritic Cells Efficiently Transport Influenza Virus to the Lymph Node and Load Viral Antigen onto MHC Class I for Presentation to CD8 T Cells

(2011) A. W. S. Ho et al.   JOURNAL OF IMMUNOLOGY

Plasmacytoid Dendritic Cells Promote Host Defense against Acute Pneumovirus Infection via the TLR7-MyD88-Dependent Signaling Pathway

(2011) S. Davidson et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8 + Type

(2011) K. Crozat et al.   JOURNAL OF IMMUNOLOGY

Susceptibility to Infection and Inflammatory Response Following Influenza Virus (H1N1, A/PR/8/34) Challenge: Role of Macrophages

(2011) E. Angela Murphy et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Major Histocompatibility Complex Class II Expression and Hemagglutinin Subtype Influence the Infectivity of Type A Influenza Virus for Respiratory Dendritic Cells

(2011) K. M. Hargadon et al.   JOURNAL OF VIROLOGY

Rapid Host Defense against Aspergillus fumigatus Involves Alveolar Macrophages with a Predominance of Alternatively Activated Phenotype

(2011) Shikha Bhatia et al.   PLoS One

Microbiota regulates immune defense against respiratory tract influenza A virus infection

(2011) T. Ichinohe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory Monocytes and Neutrophils Are Licensed to Kill during Memory Responses In Vivo

(2011) Emilie Narni-Mancinelli et al.   PLoS Pathogens

Unique Type I Interferon Responses Determine the Functional Fate of Migratory Lung Dendritic Cells during Influenza Virus Infection

(2011) Bruno Moltedo et al.   PLoS Pathogens

Type I Interferon Signaling Regulates Ly6Chi Monocytes and Neutrophils during Acute Viral Pneumonia in Mice

(2011) Sang-Uk Seo et al.   PLoS Pathogens

Highly Pathogenic Avian Influenza Virus H5N1 Infects Alveolar Macrophages without Virus Production or Excessive TNF-Alpha Induction

(2011) Debby van Riel et al.   PLoS Pathogens

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas

(2010) Cheolho Cheong et al.   CELL

From skin dendritic cells to a simplified classification of human and mouse dendritic cell subsets

(2010) Martin Guilliams et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Contrasting roles of macrophages and dendritic cells in controlling initial pulmonary Brucella infection

(2010) Cristel Archambaud et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

E-Cadherin Marks a Subset of Inflammatory Dendritic Cells that Promote T Cell-Mediated Colitis

(2010) Karima R.R. Siddiqui et al.   IMMUNITY

Type I Interferons Regulate Cytolytic Activity of Memory CD8+ T Cells in the Lung Airways during Respiratory Virus Challenge

(2010) Jacob E. Kohlmeier et al.   IMMUNITY

Peripheral CD103+dendritic cells form a unified subset developmentally related to CD8α+conventional dendritic cells

(2010) Brian T. Edelson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammatory dendritic cells—not basophils—are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

(2010) Hamida Hammad et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antiviral CD8+T cell effector activities in situ are regulated by target cell type

(2010) Matthew M. Hufford et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis

(2010) Shahin Shafiani et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasmacytoid Dendritic Cells Enhance Mortality during Lethal Influenza Infections by Eliminating Virus-Specific CD8 T Cells

(2010) R. A. Langlois et al.   JOURNAL OF IMMUNOLOGY

CCR2-Antagonist Prophylaxis Reduces Pulmonary Immune Pathology and Markedly Improves Survival during Influenza Infection

(2010) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Functional Divergence among CD103+ Dendritic Cell Subpopulations following Pulmonary Poxvirus Infection

(2010) N. M. Beauchamp et al.   JOURNAL OF VIROLOGY

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4- and IFN-β-dependent

(2010) K A Shirey et al.   Mucosal Immunology

Temporal changes in dendritic cell subsets, cross-priming and costimulation via CD70 control CD8+ T cell responses to influenza

(2010) André Ballesteros-Tato et al.   NATURE IMMUNOLOGY

Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue

(2010) N. Iijima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Dendritic Cell Antigen Presentation Drives Simultaneous Cytokine Production by Effector and Regulatory T Cells in Inflamed Skin

(2009) James B. McLachlan et al.   IMMUNITY

Selective control of SIRP-α–positive airway dendritic cell trafficking through CD47 is critical for the development of TH2-mediated allergic inflammation

(2009) Marianne Raymond et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alternatively activated macrophages in infection and autoimmunity

(2009) DeLisa Fairweather et al.   JOURNAL OF AUTOIMMUNITY

Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice

(2009) Denis Bedoret et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice

(2009) Arash Shahangian et al.   JOURNAL OF CLINICAL INVESTIGATION

Accumulation of CD11b+ Lung Dendritic Cells in Response to Fungal Infection Results from the CCR2-Mediated Recruitment and Differentiation of Ly-6Chigh Monocytes

(2009) J. J. Osterholzer et al.   JOURNAL OF IMMUNOLOGY

CD4-Positive T Lymphocytes Provide a Neuroimmunological Link in the Control of Adult Hippocampal Neurogenesis

(2009) S. A. Wolf et al.   JOURNAL OF IMMUNOLOGY

Alveolar Macrophages Transport Pathogens to Lung Draining Lymph Nodes

(2009) A. C. Kirby et al.   JOURNAL OF IMMUNOLOGY

Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing

(2009) K. J. Mylonas et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell subsets in primary and secondary T cell responses at body surfaces

(2009) William R Heath et al.   NATURE IMMUNOLOGY

Respiratory Dendritic Cell Subsets Differ in Their Capacity to Support the Induction of Virus-Specific Cytotoxic CD8+ T Cell Responses

(2009) Taeg S. Kim et al.   PLoS One

Both Conventional and Interferon Killer Dendritic Cells Have Antigen-Presenting Capacity during Influenza Virus Infection

(2009) Corine H. GeurtsvanKessel et al.   PLoS One

Modeling the immune rheostat of macrophages in the lung in response to infection

(2009) J. Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

(2009) J. R. Aldridge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

(2008) K. Movahedi et al.   BLOOD

Tumor Necrosis Factor Signaling Mediates Resistance to Mycobacteria by Inhibiting Bacterial Growth and Macrophage Death

(2008) Hilary Clay et al.   IMMUNITY

Clearance of influenza virus from the lung depends on migratory langerin+CD11b−but not plasmacytoid dendritic cells

(2008) Corine H. GeurtsvanKessel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protective influenza-specific CD8 T cell responses require interactions with dendritic cells in the lungs

(2008) Jodi McGill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Optimization of methods to study pulmonary dendritic cell migration reveals distinct capacities of DC subsets to acquire soluble versus particulate antigen

(2008) Claudia Jakubzick et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Macrophage Impairment Underlies Airway Occlusion in Primary Respiratory Syncytial Virus Bronchiolitis

(2008) Jennifer L. Reed et al.   JOURNAL OF INFECTIOUS DISEASES

Alveolar Macrophages Are Indispensable for Controlling Influenza Viruses in Lungs of Pigs

(2008) H. M. Kim et al.   JOURNAL OF VIROLOGY

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

(2008) Claudia Waskow et al.   NATURE IMMUNOLOGY

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY