Emerging Opportunities for Synthetic Biology in Agriculture

Interference with Clp protease impairs carotenoid accumulation during tomato fruit ripening

(2018) Lucio D’Andrea et al.   JOURNAL OF EXPERIMENTAL BOTANY

Expression of cocoa genes in Saccharomyces cerevisiae improves cocoa butter production

(2018) Yongjun Wei et al.   Microbial Cell Factories

Strategies for microbial synthesis of high-value phytochemicals

(2018) Sijin Li et al.   Nature Chemistry

The future of CRISPR technologies in agriculture

(2018) Caixia Gao   NATURE REVIEWS MOLECULAR CELL BIOLOGY

From plant metabolic engineering to plant synthetic biology: The evolution of the design/build/test/learn cycle

(2018) Benjamin Pouvreau et al.   PLANT SCIENCE

In vitro DNA SCRaMbLE

(2018) Yi Wu et al.   Nature Communications

Rapid pathway prototyping and engineering using in vitro and in vivo synthetic genome SCRaMbLE-in methods

(2018) Wei Liu et al.   Nature Communications

Reprogramming Probiotic Lactobacillus reuteri as a Biosensor for Staphylococcus aureus Derived AIP-I Detection

(2018) David Lubkowicz et al.   ACS Synthetic Biology

Identifying knowledge gaps for gene drive research to control invasive animal species: The next CRISPR step

(2018) Dorian Moro et al.   Global Ecology and Conservation

Microbes and the Next Nitrogen Revolution

(2017) Ilje Pikaar et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Engineering yeasts as platform organisms for cannabinoid biosynthesis

(2017) Bastian Zirpel et al.   JOURNAL OF BIOTECHNOLOGY

Synthetic biology approaches for the production of plant metabolites in unicellular organisms

(2017) Tessa Moses et al.   JOURNAL OF EXPERIMENTAL BOTANY

Harvesting and blending options for lower alcohol wines: a sensory and chemical investigation

(2017) Rocco Longo et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Engineering biological systems using automated biofoundries

(2017) Ran Chao et al.   METABOLIC ENGINEERING

Step changes in leaf oil accumulation via iterative metabolic engineering

(2017) Thomas Vanhercke et al.   METABOLIC ENGINEERING

Engineered microbial biosensors based on bacterial two-component systems as synthetic biotechnology platforms in bioremediation and biorefinery

(2017) Sambandam Ravikumar et al.   Microbial Cell Factories

Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae

(2017) Fenghua Chai et al.   Microbial Cell Factories

The genome of Chenopodium quinoa

(2017) David E. Jarvis et al.   NATURE

A new crop of microbe startups raises big bucks, takes on the establishment

(2017) Emily Waltz   NATURE BIOTECHNOLOGY

Large-scale recoding of a bacterial genome by iterative recombineering of synthetic DNA

(2017) Yu Heng Lau et al.   NUCLEIC ACIDS RESEARCH

Bug mapping and fitness testing of chemically synthesized chromosome X

(2017) Yi Wu et al.   SCIENCE

Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome

(2017) Yue Shen et al.   SCIENCE

Engineering the ribosomal DNA in a megabase synthetic chromosome

(2017) Weimin Zhang et al.   SCIENCE

Design of a synthetic yeast genome

(2017) Sarah M. Richardson et al.   SCIENCE

Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond

(2017) Leslie A. Mitchell et al.   SCIENCE

“Perfect” designer chromosome V and behavior of a ring derivative

(2017) Ze-Xiong Xie et al.   SCIENCE

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

(2017) Dong Niu et al.   SCIENCE

Synthetic Biology in the Driving Seat of the Bioeconomy

(2017) Yensi Flores Bueso et al.   TRENDS IN BIOTECHNOLOGY

Engineering species-like barriers to sexual reproduction

(2017) Maciej Maselko et al.   Nature Communications

Digital logic circuits in yeast with CRISPR-dCas9 NOR gates

(2017) Miles W. Gander et al.   Nature Communications

A transatlantic perspective on 20 emerging issues in biological engineering

(2017) Bonnie C Wintle et al.   eLife

Addressing Antimicrobial Resistance: An Overview of Priority Actions to Prevent Suboptimal Antimicrobial Use in Food-Animal Production

(2017) Guillaume Lhermie et al.   Frontiers in Microbiology

Expression of 16 Nitrogenase Proteins within the Plant Mitochondrial Matrix

(2017) Robert S. Allen et al.   Frontiers in Plant Science

The first near-complete assembly of the hexaploid bread wheat genome, Triticum aestivum

(2017) Aleksey V Zimin et al.   GigaScience

Designing synbiotics for improved human health

(2017) Sean M. Kearney et al.   Microbial Biotechnology

Yeast's balancing act between ethanol and glycerol production in low-alcohol wines

(2017) Hugh D. Goold et al.   Microbial Biotechnology

Seven microbial bio-processes to help the planet

(2017) Víctor de Lorenzo   Microbial Biotechnology

Rewiring carotenoid biosynthesis in plants using a viral vector

(2017) Eszter Majer et al.   Scientific Reports

Biosynthesis of therapeutic natural products using synthetic biology

(2016) Ali R. Awan et al.   ADVANCED DRUG DELIVERY REVIEWS

Synthetic genome engineering forging new frontiers for wine yeast

(2016) Isak S. Pretorius   CRITICAL REVIEWS IN BIOTECHNOLOGY

The use of unnatural amino acids to study and engineer protein function

(2016) Petra Neumann-Staubitz et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Whole-cell biosensor of cellobiose and application to wood decay detection

(2016) Maxime Toussaint et al.   JOURNAL OF BIOTECHNOLOGY

Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering

(2016) Yan Chen et al.   Microbial Cell Factories

Heterologous production of raspberry ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic enzyme fusion

(2016) Danna Lee et al.   Microbial Cell Factories

The genome of the seagrass Zostera marina reveals angiosperm adaptation to the sea

(2016) Jeanine L. Olsen et al.   NATURE

Synthetic biology’s first malaria drug meets market resistance

(2016) Mark Peplow   NATURE

Defining synonymous codon compression schemes by genome recoding

(2016) Kaihang Wang et al.   NATURE

Synchronized cycles of bacterial lysis for in vivo delivery

(2016) M. Omar Din et al.   NATURE

Production of hornless dairy cattle from genome-edited cell lines

(2016) Daniel F Carlson et al.   NATURE BIOTECHNOLOGY

Can CRISPR-Cas9 gene drives curb malaria?

(2016) Luke Alphey   NATURE BIOTECHNOLOGY

Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes

(2016) Holger Puchta   PLANT JOURNAL

Towards programmable plant genetic circuits

(2016) June I. Medford et al.   PLANT JOURNAL

Synthetic biology for production of natural and new-to-nature terpenoids in photosynthetic organisms

(2016) Philipp Arendt et al.   PLANT JOURNAL

Design and synthesis of a minimal bacterial genome

(2016) C. A. Hutchison et al.   SCIENCE

The next green movement: Plant biology for the environment and sustainability

(2016) J. M. Jez et al.   SCIENCE

The Genome Project-Write

(2016) J. D. Boeke et al.   SCIENCE

Synthetic Evolution of Metabolic Productivity Using Biosensors

(2016) Thomas C. Williams et al.   TRENDS IN BIOTECHNOLOGY

Organohalide Respiring Bacteria and Reductive Dehalogenases: Key Tools in Organohalide Bioremediation

(2016) Bat-Erdene Jugder et al.   Frontiers in Microbiology

Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements

(2016) Natalie Jing Ma et al.   Cell Systems

Whole Genome Re-Sequencing Identifies a Quantitative Trait Locus Repressing Carbon Reserve Accumulation during Optimal Growth in Chlamydomonas reinhardtii

(2016) Hugh Douglas Goold et al.   Scientific Reports

Targeted mutagenesis in chicken using CRISPR/Cas9 system

(2016) Isao Oishi et al.   Scientific Reports

Production of natural products through metabolic engineering of Saccharomyces cerevisiae

(2015) Anastasia Krivoruchko et al.   CURRENT OPINION IN BIOTECHNOLOGY

Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project

(2015) Anna Sliva et al.   GENETICS

SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes

(2015) Yue Shen et al.   GENOME RESEARCH

Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes

(2015) Yizhi Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Redesigning photosynthesis to sustainably meet global food and bioenergy demand

(2015) Donald R. Ort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complete biosynthesis of opioids in yeast

(2015) S. Galanie et al.   SCIENCE

Plant synthetic biology

(2015) Wusheng Liu et al.   TRENDS IN PLANT SCIENCE

GPCR-Based Chemical Biosensors for Medium-Chain Fatty Acids

(2015) Kuntal Mukherjee et al.   ACS Synthetic Biology

Innovative biological approaches for monitoring and improving water quality

(2015) Sanja Aracic et al.   Frontiers in Microbiology

Freedom and Responsibility in Synthetic Genomics: The Synthetic Yeast Project

(2015) Anna Sliva et al.   GENETICS

Total synthesis of a eukaryotic chromosome: Redesigning and SCRaMbLE-ing yeast

(2014) Dejana Jovicevic et al.   BIOESSAYS

Real-time, continuous detection of maltose using bioluminescence resonance energy transfer (BRET) on a microfluidic system

(2014) Nam Cao Hoai Le et al.   BIOSENSORS & BIOELECTRONICS

Integrating Biological Redesign: Where Synthetic Biology Came From and Where It Needs to Go

(2014) Jeffrey C. Way et al.   CELL

Yeast synthetic biology toolbox and applications for biofuel production

(2014) Ching-Sung Tsai et al.   FEMS YEAST RESEARCH

Recent applications of synthetic biology tools for yeast metabolic engineering

(2014) Michael K. Jensen et al.   FEMS YEAST RESEARCH

Synthetic biology approaches to engineering the nitrogen symbiosis in cereals

(2014) C. Rogers et al.   JOURNAL OF EXPERIMENTAL BOTANY

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

(2014) David Bikard et al.   NATURE BIOTECHNOLOGY

Principles of genetic circuit design

(2014) Jennifer A N Brophy et al.   NATURE METHODS

‘Fukusensor:’ a genetically engineered plant for reporting DNA damage in response to gamma radiation

(2014) Yanhui Peng et al.   PLANT BIOTECHNOLOGY JOURNAL

β-Carboxysomal proteins assemble into highly organized structures inNicotianachloroplasts

(2014) Myat T. Lin et al.   PLANT JOURNAL

Metabolic Engineering Camelina sativa with Fish Oil-Like Levels of DHA

(2014) James R. Petrie et al.   PLoS One

Altered sterol composition renders yeast thermotolerant

(2014) L. Caspeta et al.   SCIENCE

Regulating gene drives

(2014) K. A. Oye et al.   SCIENCE

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

Biosensing technology for sustainable food safety

(2014) V. Scognamiglio et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Genetic Engineering and Breeding of Drought-Resistant Crops

(2013) Honghong Hu et al.   Annual Review of Plant Biology

A Synthetic Gene Drive System for Local, Reversible Modification and Suppression of Insect Populations

(2013) Omar S. Akbari et al.   CURRENT BIOLOGY

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

A quantitative ratiometric sensor for time-resolved analysis of auxin dynamics

(2013) Sabrina Wend et al.   Scientific Reports

The global income and production effects of genetically modified (GM) crops 1996–2011

(2013) Graham Brookes et al.   GM Crops & Food-Biotechnology in Agriculture and the Food Chain

The development and application of a single-cell biosensor for the detection of l-methionine and branched-chain amino acids

(2012) Nurije Mustafi et al.   METABOLIC ENGINEERING

Opportunities and challenges for a sustainable energy future

(2012) Steven Chu et al.   NATURE

Genetic programs constructed from layered logic gates in single cells

(2012) Tae Seok Moon et al.   NATURE

Metabolic Engineering Plant Seeds with Fish Oil-Like Levels of DHA

(2012) James R. Petrie et al.   PLoS One

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Reverse Engineering: A Key Component of Systems Biology to Unravel Global Abiotic Stress Cross-Talk

(2012) Swetlana Friedel et al.   Frontiers in Plant Science

Greatly enhanced detection of a volatile ligand at femtomolar levels using bioluminescence resonance energy transfer (BRET)

(2011) Helen Dacres et al.   BIOSENSORS & BIOELECTRONICS

Programmable Ligand Detection System in Plants through a Synthetic Signal Transduction Pathway

(2011) Mauricio S. Antunes et al.   PLoS One

Genetic Engineering for Modern Agriculture: Challenges and Perspectives

(2010) Ron Mittler et al.   Annual Review of Plant Biology

Using a Riboswitch Sensor to Examine Coenzyme B12 Metabolism and Transport in E. coli

(2010) Casey C. Fowler et al.   CHEMISTRY & BIOLOGY

Limitations and prospects of natural photosynthesis for bioenergy production

(2010) AWD Larkum   CURRENT OPINION IN BIOTECHNOLOGY

Biodiesel from algae: challenges and prospects

(2010) Stuart A Scott et al.   CURRENT OPINION IN BIOTECHNOLOGY

Livestock production: recent trends, future prospects

(2010) P. K. Thornton   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome

(2008) D. G. Gibson et al.   SCIENCE