PERK Pathway Activation Promotes Intracerebral Hemorrhage Induced Secondary Brain Injury by Inducing Neuronal Apoptosis Both in Vivo and in Vitro

Injury mechanisms in acute intracerebral hemorrhage

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Effects of GSK2606414 on cell proliferation and endoplasmic reticulum stress-associated gene expression in retinal pigment epithelial cells

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Protein Folding and Misfolding, Endoplasmic Reticulum Stress in Neurodegenerative Diseases: in Trace of Novel Drug Targets

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Endoplasmic reticulum stress of Kupffer cells involved in the conversion of natural regulatory T cells to Th17 cells in liver ischemia-reperfusion injury

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Pharmacological Inhibition of PERK Attenuates Early Brain Injury After Subarachnoid Hemorrhage in Rats Through the Activation of Akt

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A1 adenosine receptor attenuates intracerebral hemorrhage-induced secondary brain injury in rats by activating the P38-MAPKAP2-Hsp27 pathway

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Re-exploring Tumor Necrosis Factor Alpha as a Target for Therapy in Intracerebral Hemorrhage

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PERK inhibition prevents tau-mediated neurodegeneration in a mouse model of frontotemporal dementia

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Zonisamide suppresses endoplasmic reticulum stress-induced neuronal cell damage in vitro and in vivo

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Endoplasmic Reticulum Stress Instigates the Rotenone Induced Oxidative Apoptotic Neuronal Death: a Study in Rat Brain

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The Neuroprotective Effect of Salubrinal in a Mouse Model of Traumatic Brain Injury

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Comparison between single and combined post-treatment with S-Methyl-N,N-diethylthiolcarbamate sulfoxide and taurine following transient focal cerebral ischemia in rat brain

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Carbon monoxide offers neuroprotection from hippocampal cell damage induced by recurrent febrile seizures through the PERK-activated ER stress pathway

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Measurement of Perihematomal Edema in Intracerebral Hemorrhage

(2015) S. Urday et al.   STROKE

Curcumin attenuates glutamate neurotoxicity in the hippocampus by suppression of ER stress-associated TXNIP/NLRP3 inflammasome activation in a manner dependent on AMPK

(2015) Ying Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

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Rethinking the Roles of Inflammation in the Intracerebral Hemorrhage

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The Pathophysiology of Intracerebral Hemorrhage Formation and Expansion

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Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress

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Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

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Intensive blood pressure reduction in acute intracerebral hemorrhage: A meta-analysis

(2014) G. Tsivgoulis et al.   NEUROLOGY

Endoplasmic reticulum stress is associated with neuroprotection against apoptosis via autophagy activation in a rat model of subarachnoid hemorrhage

(2014) Feng Yan et al.   NEUROSCIENCE LETTERS

An Update on Inflammation in the Acute Phase of Intracerebral Hemorrhage

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Oligodendrocyte-Specific Activation of PERK Signaling Protects Mice against Experimental Autoimmune Encephalomyelitis

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Endoplasmic Reticulum Membrane Reorganization Is Regulated by Ionic Homeostasis

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A New PERKspective on Neurodegeneration

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Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice

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ER stress inhibits neuronal death by promoting autophagy

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Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)

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Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

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Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

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Endoplasmic reticulum dysfunction in neurological disease

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The role of the IRE1 pathway in PBDE-47-induced toxicity in human neuroblastoma SH-SY5Y cells in vitro

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Isolation and Culture of Rat Embryonic Neural Cells: A Quick Protocol

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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

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Molecular Pathophysiology of Cerebral Hemorrhage

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Inhibition of Carbonic Anhydrase Reduces Brain Injury After Intracerebral Hemorrhage

(2011) Fuyou Guo et al.   Translational Stroke Research

Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

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Endoplasmic Reticulum Stress Plays Critical Role in Brain Damage After Cerebral Ischemia/Reperfusion in Rats

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