Inhibition of Calcium Influx Reduces Dysfunction and Apoptosis in Lipotoxic Pancreatic β-Cells via Regulation of Endoplasmic Reticulum Stress

MANAGEMENT OF ENDOCRINE DISEASE: A clinical update on tumor-induced hypoglycemia

(2014) Pedro Iglesias et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Cinnamtannin D-1 Protects Pancreatic β-Cells from Palmitic Acid-Induced Apoptosis by Attenuating Oxidative Stress

(2014) Ting Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

FFAR1 Is Involved in Both the Acute and Chronic Effects of Palmitate on Insulin Secretion

(2013) Hjalti Kristinsson et al.   ENDOCRINOLOGY

DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic β-Cells Dysfunction in db/db Mice

(2013) Peng Sun et al.   PLoS One

Nifedipine prevents etoposide-induced caspase-3 activation, prenyl transferase degradation and loss in cell viability in pancreatic β-cells

(2012) Daleep K. Arora et al.   APOPTOSIS

High glucose and free fatty acids induce beta cell apoptosis via autocrine effects of ADP acting on the P2Y13 receptor

(2012) Chanyuan Tan et al.   Purinergic Signalling

Nifedipine Protects INS-1 β-Cell from High Glucose-Induced ER Stress and Apoptosis

(2011) Yao Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Inhibition of GPR40 protects MIN6 β cells from palmitate-induced ER stress and apoptosis

(2011) Jinwei Wu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies

(2010) Adria Giacca et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

DC260126, a small-molecule antagonist of GPR40, improves insulin tolerance but not glucose tolerance in obese Zucker rats

(2010) Xiaodong Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Causes and cures for endoplasmic reticulum stress in lipotoxic β-cell dysfunction

(2010) M. Cnop et al.   DIABETES OBESITY & METABOLISM

Effects of palmitate on ER and cytosolic Ca2+ homeostasis in β-cells

(2009) Kamila S. Gwiazda et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A novel class of antagonists for the FFAs receptor GPR40

(2009) Hui Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Induces Calcium Influx Through T-type Calcium Channel and Enhances Lysosomal Exocytosis and Insulin Secretion in INS-1 Cells

(2009) Youn-Hee Kim et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Differential regulation of the ER stress response by long-chain fatty acids in the pancreatic β-cell

(2008) Eleftheria Diakogiannaki et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Inhibition of Foxo1 Protects Pancreatic Islet  -Cells Against Fatty Acid and Endoplasmic Reticulum Stress-Induced Apoptosis

(2008) S. C. Martinez et al.   DIABETES

Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4

(2008) S. Casas et al.   DIABETOLOGIA

Initiation and execution of lipotoxic ER stress in pancreatic  -cells

(2008) D. A. Cunha et al.   JOURNAL OF CELL SCIENCE

Diazoxide-induced β-cell rest reduces endoplasmic reticulum stress in lipotoxic β-cells

(2008) Ernest Sargsyan et al.   JOURNAL OF ENDOCRINOLOGY