Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases
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Title
Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases
Authors
Keywords
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Journal
Science Signaling
Volume 11, Issue 516, Pages eaan8660
Publisher
American Association for the Advancement of Science (AAAS)
Online
2018-02-08
DOI
10.1126/scisignal.aan8660
References
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Note: Only part of the references are listed.- SUMO regulates the activity of Smoothened and Costal-2 in Drosophila Hedgehog signaling
- (2017) Jie Zhang et al. Scientific Reports
- Regulation of Smoothened Trafficking and Hedgehog Signaling by the SUMO Pathway
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- Regulation of Smoothened Phosphorylation and High-Level Hedgehog Signaling Activity by a Plasma Membrane Associated Kinase
- (2016) Shuangxi Li et al. PLOS BIOLOGY
- Control of the dynamics and homeostasis of theDrosophilaHedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases
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- Hedgehog induces formation of PKA-Smoothened complexes to promote Smoothened phosphorylation and pathway activation
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- Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex
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- Drosophila Vps36 regulates Smo trafficking in Hedgehog signaling
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- Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover
- (2013) Shoujun Huang et al. PLOS BIOLOGY
- USP8 Promotes Smoothened Signaling by Preventing Its Ubiquitination and Changing Its Subcellular Localization
- (2012) Ruohan Xia et al. PLOS BIOLOGY
- Hedgehog-Regulated Ubiquitination Controls Smoothened Trafficking and Cell Surface Expression in Drosophila
- (2012) Shuang Li et al. PLOS BIOLOGY
- Gli Proteins in Development and Disease
- (2011) Chi-chung Hui et al. Annual Review of Cell and Developmental Biology
- Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened
- (2011) Yongbin Chen et al. PLOS BIOLOGY
- Role of the Drosophila Non-Visual ß-Arrestin Kurtz in Hedgehog Signalling
- (2011) Cristina Molnar et al. PLoS Genetics
- Mechanism and evolution of cytosolic Hedgehog signal transduction
- (2010) C. W. Wilson et al. DEVELOPMENT
- G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila
- (2010) Y. Chen et al. GENES & DEVELOPMENT
- Self-Induced Patched Receptor Down-Regulation Modulates Cell Sensitivity to the Hedgehog Morphogen Gradient
- (2010) A. Casali Science Signaling
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- (2009) Andreu Casali et al. Cell Stem Cell
- Regulation of Smoothened by Drosophila G-protein-coupled receptor kinases
- (2009) Shuofei Cheng et al. DEVELOPMENTAL BIOLOGY
- Hedgehog Signaling in Development and Cancer
- (2008) Jin Jiang et al. DEVELOPMENTAL CELL
- Nedd4 Mediates Agonist-dependent Ubiquitination, Lysosomal Targeting, and Degradation of the β2-Adrenergic Receptor
- (2008) Sudha K. Shenoy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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