Switch of PKA substrates from Cubitus interruptus to Smoothened in the Hedgehog signalosome complex

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner

(2012) Junkai Fan et al.   DEVELOPMENTAL BIOLOGY

Distinct Phosphorylations on Kinesin Costal-2 Mediate Differential Hedgehog Signaling Strength

(2012) Nadia Ranieri et al.   DEVELOPMENTAL CELL

Variation in Transit

(2011) P. R. Stern   Science Signaling

Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

(2011) Yongbin Chen et al.   PLOS BIOLOGY

Dynamic phosphorylation of the kinesin Costal-2 in vivo reveals requirement of fused kinase activity for all levels of hedgehog signalling

(2010) S. Raisin et al.   DEVELOPMENTAL BIOLOGY

G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila

(2010) Y. Chen et al.   GENES & DEVELOPMENT

WAVE Forms Hetero- and Homo-oligomeric Complexes at Integrin Junctions inDrosophilaVisualized by Bimolecular Fluorescence Complementation

(2010) Christina Gohl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Casein Kinase 2 Promotes Hedgehog Signaling by Regulating both Smoothened and Cubitus Interruptus

(2010) Hongge Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluating Smoothened as a G-protein-coupled receptor for Hedgehog signalling

(2010) Katie L. Ayers et al.   TRENDS IN CELL BIOLOGY

G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling

(2008) Stacey K. Ogden et al.   NATURE

Fluorescence complementation: an emerging tool for biological research

(2008) Y. John Shyu et al.   TRENDS IN BIOTECHNOLOGY