Control of the dynamics and homeostasis of theDrosophilaHedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases

The role of ciliary trafficking in Hedgehog receptor signaling

(2015) Jynho Kim et al.   Science Signaling

The role of ciliary trafficking in Hedgehog receptor signaling

(2015) Jynho Kim et al.   Science Signaling

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

(2014) Shen Yue et al.   eLife

The ubiquitin code and its decoding machinery in the endocytic pathway

(2013) H. Tanno et al.   JOURNAL OF BIOCHEMISTRY

The mechanisms of Hedgehog signalling and its roles in development and disease

(2013) James Briscoe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hedgehog Agonist Therapy Corrects Structural and Cognitive Deficits in a Down Syndrome Mouse Model

(2013) I. Das et al.   Science Translational Medicine

Activation of Smurf E3 Ligase Promoted by Smoothened Regulates Hedgehog Signaling through Targeting Patched Turnover

(2013) Shoujun Huang et al.   PLOS BIOLOGY

USP8 Promotes Smoothened Signaling by Preventing Its Ubiquitination and Changing Its Subcellular Localization

(2012) Ruohan Xia et al.   PLOS BIOLOGY

Hedgehog-Regulated Ubiquitination Controls Smoothened Trafficking and Cell Surface Expression in Drosophila

(2012) Shuang Li et al.   PLOS BIOLOGY

Mechanisms and functions of Hedgehog signalling across the metazoa

(2011) Philip W. Ingham et al.   NATURE REVIEWS GENETICS

Drosophila Ndfip is a novel regulator of Notch signaling

(2010) H E Dalton et al.   CELL DEATH AND DIFFERENTIATION

Self-Induced Patched Receptor Down-Regulation Modulates Cell Sensitivity to the Hedgehog Morphogen Gradient

(2010) A. Casali   Science Signaling

A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain

(2009) Nicholas F Garrone et al.   BMC CELL BIOLOGY

The deubiquitinases USP33 and USP20 coordinate β2 adrenergic receptor recycling and resensitization

(2009) Magali Berthouze et al.   EMBO JOURNAL

Regulation of the RSP5 Ubiquitin Ligase by an Intrinsic Ubiquitin-binding Site

(2009) Michael E. French et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polyubiquitination by HECT E3s and the Determinants of Chain Type Specificity

(2009) H. C. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Physiological functions of the HECT family of ubiquitin ligases

(2009) Daniela Rotin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy

(2009) Suzie J. Scales et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Versatile role of the yeast ubiquitin ligase Rsp5p in intracellular trafficking: Figure 1

(2008) Naima Belgareh-Touzé et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Identification of c-Cbl as a New Ligase for Insulin-like Growth Factor-I Receptor with Distinct Roles from Mdm2 in Receptor Ubiquitination and Endocytosis

(2008) B. Sehat et al.   CANCER RESEARCH

Ubiquitin ligase adaptors: Regulators of ubiquitylation and endocytosis of plasma membrane proteins

(2008) Sébastien Léon et al.   EXPERIMENTAL CELL RESEARCH

Regulation of the Epithelial Na+Channel by the Protein Kinase CK2

(2008) Tanja Bachhuber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endocytosis: A Positive or a Negative Influence on Wnt Signalling?

(2007) Maria Gagliardi et al.   TRAFFIC

Fibroblast growth factors and Hedgehogs: at the heart of the epicardial signaling center

(2007) Kory J. Lavine et al.   TRENDS IN GENETICS