CRISPR-Based Targeted Epigenetic Editing Enables Gene Expression Modulation of the Silenced Beta-Galactoside Alpha-2,6-Sialyltransferase 1 in CHO Cells
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Title
CRISPR-Based Targeted Epigenetic Editing Enables Gene Expression Modulation of the Silenced Beta-Galactoside Alpha-2,6-Sialyltransferase 1 in CHO Cells
Authors
Keywords
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Journal
Biotechnology Journal
Volume -, Issue -, Pages 1700217
Publisher
Wiley
Online
2018-05-26
DOI
10.1002/biot.201700217
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Note: Only part of the references are listed.- RNA-Seq Highlights High Clonal Variation in Monoclonal Antibody Producing CHO Cells
- (2018) Camila A. Orellana et al. Biotechnology Journal
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- (2017) Frank Lyko NATURE REVIEWS GENETICS
- Growth Rate Changes in CHO Host Cells Are Associated with Karyotypic Heterogeneity
- (2017) Jong Youn Baik et al. Biotechnology Journal
- Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time
- (2016) Julia Feichtinger et al. BIOTECHNOLOGY AND BIOENGINEERING
- Editing DNA Methylation in the Mammalian Genome
- (2016) X. Shawn Liu et al. CELL
- Genetic analysis of the clonal stability of Chinese hamster ovary cells for recombinant protein production
- (2016) Hongwen Li et al. Molecular BioSystems
- Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions
- (2016) Sumiyo Morita et al. NATURE BIOTECHNOLOGY
- Repurposing the CRISPR-Cas9 system for targeted DNA methylation
- (2016) Aleksandar Vojta et al. NUCLEIC ACIDS RESEARCH
- Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation
- (2016) James I. McDonald et al. Biology Open
- Glycoengineering of Chinese hamster ovary cells for enhanced erythropoietin N-glycan branching and sialylation
- (2015) Bojiao Yin et al. BIOTECHNOLOGY AND BIOENGINEERING
- Chinese hamster ovary (CHO) host cell engineering to increase sialylation of recombinant therapeutic proteins by modulating sialyltransferase expression
- (2015) Nan Lin et al. BIOTECHNOLOGY PROGRESS
- Digging deep into “dirty” drugs – modulation of the methylation machinery
- (2015) Lisa Pleyer et al. DRUG METABOLISM REVIEWS
- Stability of single copy transgene expression in CHOK1 cells is affected by histone modifications but not by DNA methylation
- (2015) Shawal Spencer et al. JOURNAL OF BIOTECHNOLOGY
- The DNA methylation landscape of Chinese hamster ovary (CHO) DP-12 cells
- (2015) Anna Wippermann et al. JOURNAL OF BIOTECHNOLOGY
- A common glycan structure on immunoglobulin G for enhancement of effector functions
- (2015) Chin-Wei Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CCTop: An Intuitive, Flexible and Reliable CRISPR/Cas9 Target Prediction Tool
- (2015) Manuel Stemmer et al. PLoS One
- Overexpression of microRNAs enhances recombinant protein production in Chinese hamster ovary cells
- (2014) Wan Ping Loh et al. Biotechnology Journal
- Identifying and engineering promoters for high level and sustainable therapeutic recombinant protein production in cultured mammalian cells
- (2014) Steven C. L. Ho et al. BIOTECHNOLOGY LETTERS
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
- (2014) Marvin E. Tanenbaum et al. CELL
- Addition of Valproic Acid to CHO Cell Fed-Batch Cultures Improves Monoclonal Antibody Titers
- (2014) William C. Yang et al. MOLECULAR BIOTECHNOLOGY
- Biopharmaceutical benchmarks 2014
- (2014) Gary Walsh NATURE BIOTECHNOLOGY
- Establishment of a CpG island microarray for analyses of genome-wide DNA methylation in Chinese hamster ovary cells
- (2013) Anna Wippermann et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
- (2013) Lei S. Qi et al. CELL
- Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics
- (2013) Linn Fagerberg et al. MOLECULAR & CELLULAR PROTEOMICS
- TET enzymes, TDG and the dynamics of DNA demethylation
- (2013) Rahul M. Kohli et al. NATURE
- Chinese hamster genome sequenced from sorted chromosomes
- (2013) Karina Brinkrolf et al. NATURE BIOTECHNOLOGY
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome
- (2013) Nathan E Lewis et al. NATURE BIOTECHNOLOGY
- CRISPR RNA–guided activation of endogenous human genes
- (2013) Morgan L Maeder et al. NATURE METHODS
- Sialic acid metabolism and sialyltransferases: natural functions and applications
- (2012) Yanhong Li et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Functional heterogeneity and heritability in CHO cell populations
- (2012) Sarah L. Davies et al. BIOTECHNOLOGY AND BIOENGINEERING
- Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture
- (2012) Laura A Bailey et al. BIOTECHNOLOGY AND BIOENGINEERING
- DNA Methylation and Its Basic Function
- (2012) Lisa D Moore et al. NEUROPSYCHOPHARMACOLOGY
- A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies
- (2011) Minsoo Kim et al. BIOTECHNOLOGY AND BIOENGINEERING
- Promoter methylation and transgene copy numbers predict unstable protein production in recombinant chinese hamster ovary cell lines
- (2011) Andrea Osterlehner et al. BIOTECHNOLOGY AND BIOENGINEERING
- CpG islands and the regulation of transcription
- (2011) A. M. Deaton et al. GENES & DEVELOPMENT
- Growth, productivity and protein glycosylation in a CHO EpoFc producer cell line adapted to glutamine-free growth
- (2011) Michael Taschwer et al. JOURNAL OF BIOTECHNOLOGY
- The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell line
- (2011) Xun Xu et al. NATURE BIOTECHNOLOGY
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines
- (2010) Yuansheng Yang et al. JOURNAL OF BIOTECHNOLOGY
- Conservation and divergence of methylation patterning in plants and animals
- (2010) S. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation
- (2010) A. Zemach et al. SCIENCE
- Intraclonal Protein Expression Heterogeneity in Recombinant CHO Cells
- (2009) Warren Pilbrough et al. PLoS One
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- A study of monoclonal antibody-producing CHO cell lines: What makes a stable high producer?
- (2008) Janet Chusainow et al. BIOTECHNOLOGY AND BIOENGINEERING
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