Enhanced bone defect repairing effects in glucocorticoid-induced osteonecrosis of the femoral head using a porous nano-lithium-hydroxyapatite/gelatin microsphere/erythropoietin composite scaffold

Nectin-4 is a breast cancer stem cell marker that induces WNT/β-catenin signaling via Pi3k/Akt axis

(2017) Sumit Siddharth et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Promotion of in vivo degradability, vascularization and osteogenesis of calcium sulfate-based bone cements containing nanoporous lithium doping magnesium silicate

(2017) Liehu Cao et al.   International Journal of Nanomedicine

Effectiveness of tissue engineered chitosan-gelatin composite scaffold loaded with human platelet gel in regeneration of critical sized radial bone defect in rat

(2017) Ahmad Oryan et al.   JOURNAL OF CONTROLLED RELEASE

TRPM4 regulates Akt/GSK3-β activity and enhances β-catenin signaling and cell proliferation in prostate cancer cells

(2017) Alfredo I. Sagredo et al.   Molecular Oncology

Long-term outcomes of transtrochanteric rotational osteotomy for non-traumatic osteonecrosis of the femoral head

(2017) D. Morita et al.   Bone & Joint Journal

Gastrointestinal cancer cells treatment with bevacizumab activates a VEGF autoregulatory mechanism involving telomerase catalytic subunit hTERT via PI3K-AKT, HIF-1α and VEGF receptors

(2017) Nadine Mahfouz et al.   PLoS One

Acceleration of bone regeneration by activating Wnt/β-catenin signalling pathway via lithium released from lithium chloride/calcium phosphate cement in osteoporosis

(2017) Li Li et al.   Scientific Reports

Activation of aryl hydrocarbon receptor mediates suppression of hypoxia-inducible factor-dependent erythropoietin expression by indoxyl sulfate

(2016) Hirobumi Asai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Does Wrist Arthrodesis With Structural Iliac Crest Bone Graft After Wide Resection of Distal Radius Giant Cell Tumor Result in Satisfactory Function and Local Control?

(2016) Tao Wang et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Impaired osteogenic differentiation associated with connexin43/microRNA-206 in steroid-induced avascular necrosis of the femoral head

(2016) Gang Liu et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Cellular interaction influenced by surface modification strategies of gelatin-based nanoparticles

(2016) Wai Hei Tse et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Lithium chloride enhances bone regeneration and implant osseointegration in osteoporotic conditions

(2016) Yifan Jin et al.   JOURNAL OF BONE AND MINERAL METABOLISM

In vitro and in vivo evaluation of calcium phosphate composite scaffolds containing BMP-VEGF loaded PLGA microspheres for the treatment of avascular necrosis of the femoral head

(2016) Hao-Xuan Zhang et al.   Materials Science & Engineering C-Materials for Biological Applications

In vitro study on the degradation of lithium-doped hydroxyapatite for bone tissue engineering scaffold

(2016) Yaping Wang et al.   Materials Science & Engineering C-Materials for Biological Applications

C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways

(2016) JiaYuan Chen et al.   Stem Cell Research & Therapy

Surface modification of strontium-doped porous bioactive ceramic scaffolds via poly(DOPA) coating and immobilizing silk fibroin for excellent angiogenic and osteogenic properties

(2016) Xu Wang et al.   Biomaterials Science

Erythropoietin-mediated expression of placenta growth factor is regulated via activation of hypoxia-inducible factor-1α and post-transcriptionally bymiR-214in sickle cell disease

(2015) Caryn S. Gonsalves et al.   BIOCHEMICAL JOURNAL

Phytomolecule icaritin incorporated PLGA/TCP scaffold for steroid-associated osteonecrosis: Proof-of-concept for prevention of hip joint collapse in bipedal emus and mechanistic study in quadrupedal rabbits

(2015) Ling Qin et al.   BIOMATERIALS

Osteonecrosis repair with bone marrow cell therapies: State of the clinical art

(2015) Philippe Hernigou et al.   BONE

Transplantation of hypoxia preconditioned bone marrow mesenchymal stem cells enhances angiogenesis and osteogenesis in rabbit femoral head osteonecrosis

(2015) Lihong Fan et al.   BONE

Prevalence of Nontraumatic Osteonecrosis of the Femoral Head and its Associated Risk Factors in the Chinese Population: Results from a Nationally Representative Survey

(2015) De-Wei Zhao et al.   CHINESE MEDICAL JOURNAL

Lithium chloride attenuates the abnormal osteogenic/adipogenic differentiation of bone marrow-derived mesenchymal stem cells obtained from rats with steroid-related osteonecrosis by activating the β-catenin pathway

(2015) ZEFENG YU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Administration of erythropoietin exerts protective effects against glucocorticoid-induced osteonecrosis of the femoral head in rats

(2014) SEN CHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Analyzing the behavior of a porous nano-hydroxyapatite/polyamide 66 (n-HA/PA66) composite for healing of bone defects

(2014) Yan Xiong et al.   International Journal of Nanomedicine

Long lasting outcome of hydroxyapatite-coated implants in primary knee arthroplasty: a continuous series of two hundred and seventy total knee arthroplasties at fifteen to twenty two years of clinical follow-up

(2014) Jean-Alain Epinette   INTERNATIONAL ORTHOPAEDICS

Surface modification of titanium substrates with silver nanoparticles embedded sulfhydrylated chitosan/gelatin polyelectrolyte multilayer films for antibacterial application

(2014) Wen Li et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Effect of dissolution/precipitation on the residual stress redistribution of plasma-sprayed hydroxyapatite coating on titanium substrate in simulated body fluid (SBF)

(2014) Achariya Rakngarm Nimkerdphol et al.   Journal of the Mechanical Behavior of Biomedical Materials

Epidemiology of nontraumatic osteonecrosis of the femoral head in Japan

(2014) Kazuma Ikeuchi et al.   Modern Rheumatology

Curcumin increases rat mesenchymal stem cell osteoblast differentiation but inhibits adipocyte differentiation

(2014) Huilin Yang et al.   Pharmacognosy Magazine

EPO Promotes Bone Repair through Enhanced Cartilaginous Callus Formation and Angiogenesis

(2014) Lin Wan et al.   PLoS One

Erythropoietin Promotes the Protective Properties of Transplanted Endothelial Progenitor Cells Against Acute Lung Injury via PI3K/Akt Pathway

(2014) Ruoyu Hu et al.   SHOCK

Sequential delivery of BMP-2 and IGF-1 using a chitosan gel with gelatin microspheres enhances early osteoblastic differentiation

(2012) Sungwoo Kim et al.   Acta Biomaterialia

Comparison of micro- vs. nanostructured colloidal gelatin gels for sustained delivery of osteogenic proteins: Bone morphogenetic protein-2 and alkaline phosphatase

(2012) Huanan Wang et al.   BIOMATERIALS

SMND-309 promotes angiogenesis in human umbilical vein endothelial cells through activating erythropoietin receptor/STAT3/VEGF pathways

(2012) Guangying Du et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glycogen Synthase Kinase-3β Is Involved in Ligand-Dependent Activation of Transcription and Cellular Localization of the Glucocorticoid Receptor

(2012) Camila Rubio-Patiño et al.   MOLECULAR ENDOCRINOLOGY

Various preparation methods of highly porous hydroxyapatite/polymer nanoscale biocomposites for bone regeneration

(2011) Fangfang Sun et al.   Acta Biomaterialia

In vitro study of enhanced osteogenesis induced by HIF-1α-transduced bone marrow stem cells

(2011) D. Zou et al.   CELL PROLIFERATION

Bioinspired catecholic chemistry for surface modification

(2011) Qian Ye et al.   CHEMICAL SOCIETY REVIEWS

Are the results of multiple drilling and alendronate for osteonecrosis of the femoral head better than those of multiple drilling? A pilot study

(2011) Pengde Kang et al.   JOINT BONE SPINE

Erythropoietin mediated bone formation is regulated by mTOR signaling

(2011) Jinkoo Kim et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Steroid induced osteonecrosis: An analysis of steroid dosing risk

(2010) Christian Powell et al.   AUTOIMMUNITY REVIEWS

A deep investigation into the adipogenesis mechanism: Profile of microRNAs regulating adipogenesis by modulating the canonical Wnt/β-catenin signaling pathway

(2010) Limei Qin et al.   BMC GENOMICS

Lithium chloride attenuates BMP-2 signaling and inhibits osteogenic differentiation through a novel WNT/GSK3- independent mechanism

(2010) Jingjing Li et al.   BONE

Emerging Ideas: Treatment of Precollapse Osteonecrosis Using Stem Cells and Growth Factors

(2010) Quanjun Cui et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Nationwide Epidemiologic Survey of Idiopathic Osteonecrosis of the Femoral Head

(2010) Wakaba Fukushima et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Erythropoetin as a novel agent with pleiotropic effects against acute lung injury

(2010) Sotirios Kakavas et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Silicate, borosilicate, and borate bioactive glass scaffolds with controllable degradation rate for bone tissue engineering applications. I. Preparation and in vitro degradation

(2010) Qiang Fu et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Erythropoietin protects against diabetes through direct effects on pancreatic β cells

(2010) Diana Choi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Erythropoietin Couples Hematopoiesis with Bone Formation

(2010) Yusuke Shiozawa et al.   PLoS One

Bone tissue engineering therapeutics: controlled drug delivery in three-dimensional scaffolds

(2009) V. Mourino et al.   Journal of the Royal Society Interface

A Physical Mechanism for Coupling Bone Resorption and Formation in Adult Human Bone

(2008) Thomas Levin Andersen et al.   AMERICAN JOURNAL OF PATHOLOGY

Lithium's effect on bone mineral density

(2008) Ali Zamani et al.   BONE

Biomimetic Systems for Hydroxyapatite Mineralization Inspired By Bone and Enamel

(2008) Liam C. Palmer et al.   CHEMICAL REVIEWS

Distribution of TRAP-positive cells and expression of HIF-1α, VEGF, and FGF-2 in the reparative reaction in patients with osteonecrosis of the femoral head

(2008) Weizhe Li et al.   JOURNAL OF ORTHOPAEDIC RESEARCH