Lupus-like autoimmune disease caused by a lack of Xkr8, a caspase-dependent phospholipid scramblase

Apoptosis and Clearance of Apoptotic Cells

(2018) Shigekazu Nagata   Annual Review of Immunology

Efferocytosis of dying cells differentially modulate immunological outcomes in tumor microenvironment

(2017) Sushil Kumar et al.   IMMUNOLOGICAL REVIEWS

Identification of the macrophage-specific promoter signature in FANTOM5 mouse embryo developmental time course data

(2017) Kim M. Summers et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis

(2017) Yuichi Yanagihashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

(2016) Vanja Sisirak et al.   CELL

Do not let death do us part: ‘find-me’ signals in communication between dying cells and the phagocytes

(2016) C B Medina et al.   CELL DEATH AND DIFFERENTIATION

Exposure of phosphatidylserine on the cell surface

(2016) S Nagata et al.   CELL DEATH AND DIFFERENTIATION

Clearance of apoptotic neutrophils and resolution of inflammation

(2016) Mallary C. Greenlee-Wacker   IMMUNOLOGICAL REVIEWS

Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction

(2016) Michio Nakaya et al.   JOURNAL OF CLINICAL INVESTIGATION

Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane

(2016) Edouard M. Bevers et al.   PHYSIOLOGICAL REVIEWS

Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure

(2016) Jun Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Programmed necrosis in inflammation: Toward identification of the effector molecules

(2016) D. Wallach et al.   SCIENCE

Human Type IV P-type ATPases That Work as Plasma Membrane Phospholipid Flippases and Their Regulation by Caspase and Calcium

(2015) Katsumori Segawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exposure of Phosphatidylserine by Xk-related Protein Family Members during Apoptosis

(2014) Jun Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure

(2014) K. Segawa et al.   SCIENCE

Differential TAM receptor–ligand–phospholipid interactions delimit differential TAM bioactivities

(2014) Erin D Lew et al.   eLife

Rhythmic Modulation of the Hematopoietic Niche through Neutrophil Clearance

(2013) María Casanova-Acebes et al.   CELL

Prolonged Apoptotic Cell Accumulation in Germinal Centers of Mer-Deficient Mice Causes Elevated B Cell and CD4+ Th Cell Responses Leading to Autoantibody Production

(2013) T. N. Khan et al.   JOURNAL OF IMMUNOLOGY

Regulation of Circulating Neutrophil Numbers under Homeostasis and in Disease

(2013) Natasha Strydom et al.   Journal of Innate Immunity

Xk-Related Protein 8 and CED-8 Promote Phosphatidylserine Exposure in Apoptotic Cells

(2013) J. Suzuki et al.   SCIENCE

Mechanisms tagging senescent red blood cells for clearance in healthy humans

(2013) Hans U. Lutz et al.   Frontiers in Physiology

IL-21 Receptor Is Required for the Systemic Accumulation of Activated B and T Lymphocytes in MRL/MpJ-Faslpr/lpr/J Mice

(2012) A. L. Rankin et al.   JOURNAL OF IMMUNOLOGY

Caspase Substrates and Cellular Remodeling

(2011) Emily D. Crawford et al.   Annual Review of Biochemistry

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

Molecular analysis of neutrophil spontaneous apoptosis reveals a strong role for the pro-apoptotic BH3-only protein Noxa

(2011) S Kirschnek et al.   CELL DEATH AND DIFFERENTIATION

Peculiarities of cell death mechanisms in neutrophils

(2011) B Geering et al.   CELL DEATH AND DIFFERENTIATION

Autoimmunity in MFG-E8–deficient mice is associated with altered trafficking and enhanced cross-presentation of apoptotic cell antigens

(2011) YuFeng Peng et al.   JOURNAL OF CLINICAL INVESTIGATION

Two-Step Engulfment of Apoptotic Cells

(2011) S. Toda et al.   MOLECULAR AND CELLULAR BIOLOGY

The Distribution and Function of Phosphatidylserine in Cellular Membranes

(2010) Peter A. Leventis et al.   Annual Review of Biophysics

The role of defective clearance of apoptotic cells in systemic autoimmunity

(2010) Luis E. Muñoz et al.   Nature Reviews Rheumatology

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

(2010) R. Rodriguez-Manzanet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory macrophages, and not only neutrophils, die by apoptosis during acute peritonitis

(2009) Elzbieta Kolaczkowska et al.   IMMUNOBIOLOGY