Do not let death do us part: ‘find-me’ signals in communication between dying cells and the phagocytes

Mechanosensitive pannexin-1 channels mediate microvascular metastatic cell survival

(2015) Paul W. Furlow et al.   NATURE CELL BIOLOGY

Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53

(2015) K. W. Yoon et al.   SCIENCE

A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells

(2015) Marie Billaud et al.   Science Signaling

An Apoptotic ‘Eat Me’ Signal: Phosphatidylserine Exposure

(2015) Katsumori Segawa et al.   TRENDS IN CELL BIOLOGY

Defective apical extrusion signaling contributes to aggressive tumor hallmarks

(2015) Yapeng Gu et al.   eLife

A molecular signature in the pannexin1 intracellular loop confers channel activation by the α1 adrenoreceptor in smooth muscle cells

(2015) Marie Billaud et al.   Science Signaling

Pannexin channels and their links to human disease

(2014) Silvia Penuela et al.   BIOCHEMICAL JOURNAL

Intrinsic properties and regulation of Pannexin 1 channel

(2014) Yu-Hsin Chiu et al.   Channels

Unexpected link between an antibiotic, pannexin channels and apoptosis

(2014) Ivan K. H. Poon et al.   NATURE

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells

(2014) Hiroshi Yamaguchi et al.   eLife

The pannexins: past and present

(2014) Stephen R. Bond et al.   Frontiers in Physiology

Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis

(2013) Sarah E. Lutz et al.   PLoS One

Fractalkine: A Survivor's Guide

(2012) Gemma E. White et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Release of lysophospholipid ‘find-me’ signals during apoptosis requires the ATP-binding cassette transporter A1

(2012) Christoph Peter et al.   AUTOIMMUNITY

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

(2012) Jie Liang et al.   CANCER CELL

Pannexin 1, an ATP Release Channel, Is Activated by Caspase Cleavage of Its Pore-associated C-terminal Autoinhibitory Region

(2012) Joanna K. Sandilos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular function and molecular structure of ecto-nucleotidases

(2012) Herbert Zimmermann et al.   Purinergic Signalling

Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

(2011) Yapeng Gu et al.   JOURNAL OF CELL BIOLOGY

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

(2011) Y. Qu et al.   JOURNAL OF IMMUNOLOGY

Neuroaxonal Dystrophy in Calcium-Independent Phospholipase A2  Deficiency Results from Insufficient Remodeling and Degeneration of Mitochondrial and Presynaptic Membranes

(2011) G. Beck et al.   JOURNAL OF NEUROSCIENCE

Pannexins in ischemia-induced neurodegeneration

(2011) P. Bargiotas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The purinergic receptor P2Y2 receptor mediates chemotaxis of dendritic cells and eosinophils in allergic lung inflammation

(2010) T. Müller et al.   ALLERGY

Dangerous attraction: phagocyte recruitment and danger signals of apoptotic and necrotic cells

(2010) Christoph Peter et al.   APOPTOSIS

Cleavage of sphingosine kinase 2 by caspase-1 provokes its release from apoptotic cells

(2010) A. Weigert et al.   BLOOD

Autoimmunity and the Clearance of Dead Cells

(2010) Shigekazu Nagata et al.   CELL

Apoptosis: Opening PANdora's BoX

(2010) Christoph Peter et al.   CURRENT BIOLOGY

Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages

(2010) Camila Marques-da-Silva et al.   IMMUNOBIOLOGY

Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression

(2010) Mariko Noda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clearance of apoptotic cells: implications in health and disease

(2010) Michael R. Elliott et al.   JOURNAL OF CELL BIOLOGY

Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production

(2010) Monika Riederer et al.   JOURNAL OF LIPID RESEARCH

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Autocrine Purinergic Receptor Signaling Is Essential for Macrophage Chemotaxis

(2010) M. Kronlage et al.   Science Signaling

Mouse dendritic cells matured by ingestion of apoptotic blebs induce T cells to produce interleukin-17

(2009) Justin H. Fransen et al.   ARTHRITIS AND RHEUMATISM

Both early and late apoptotic blebs are taken up by DC and induce IL-6 production

(2009) J. H. Fransen et al.   AUTOIMMUNITY

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

(2009) M. Nakayama et al.   BLOOD

Fractalkine has anti-apoptotic and proliferative effects on human vascular smooth muscle cells via epidermal growth factor receptor signalling

(2009) Gemma E. White et al.   CARDIOVASCULAR RESEARCH

Distinct Roles of Sphingosine Kinase 1 and 2 in Murine Collagen-Induced Arthritis

(2009) W.-Q. Lai et al.   JOURNAL OF IMMUNOLOGY

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE

CX3CL1/fractalkine is released from apoptotic lymphocytes to stimulate macrophage chemotaxis

(2008) L. A. Truman et al.   BLOOD

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

Apoptosis induces expression of sphingosine kinase 1 to release sphingosine-1-phosphate as a “come-and-get-me” signal

(2008) David R. Gude et al.   FASEB JOURNAL

A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis

(2008) Ashley J. Snider et al.   FASEB JOURNAL

Thymosin β4 is involved in stabilin-2-mediated apoptotic cell engulfment

(2008) Sung-Jin Lee et al.   FEBS LETTERS

Requirement of Adaptor Protein GULP during Stabilin-2-mediated Cell Corpse Engulfment

(2008) Seung-Yoon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroaxonal Dystrophy Caused by Group VIA Phospholipase A2 Deficiency in Mice: A Model of Human Neurodegenerative Disease

(2008) K. Shinzawa et al.   JOURNAL OF NEUROSCIENCE

A pathway for phagosome maturation during engulfment of apoptotic cells

(2008) Jason M. Kinchen et al.   NATURE CELL BIOLOGY

Platelet microparticles contain active caspase 3

(2008) Anita N. Böing et al.   PLATELETS

Fractalkine Deficiency Markedly Reduces Macrophage Accumulation and Atherosclerotic Lesion Formation in CCR2 −/− Mice

(2007) Noah Saederup et al.   CIRCULATION