Transamidation of N-acyl-glutarimides with amines

Pd-PEPPSI: Pd-NHC Precatalyst for Suzuki–Miyaura Cross-Coupling Reactions of Amides

(2017) Peng Lei et al.   JOURNAL OF ORGANIC CHEMISTRY

Resonance Destabilization in N-Acylanilines (Anilides): Electronically-Activated Planar Amides of Relevance in N–C(O) Cross-Coupling

(2017) Roman Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

Ni-Catalyzed Alkene Carboacylation via Amide C–N Bond Activation

(2017) James A. Walker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Factors Controlling the Reactivity and Chemoselectivity of Resonance Destabilized Amides in Ni-Catalyzed Decarbonylative and Nondecarbonylative Suzuki-Miyaura Coupling

(2017) Chong-Lei Ji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Acylsuccinimides: twist-controlled, acyl-transfer reagents in Suzuki–Miyaura cross-coupling by N–C amide bond activation

(2017) Yuki Osumi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Sc(OTf)3-catalyzed synthesis of anhydrides from twisted amides

(2017) Yongmei Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nickel-Catalyzed C–CN Bond Formation via Decarbonylative Cyanation of Esters, Amides, and Intramolecular Recombination Fragment Coupling of Acyl Cyanides

(2017) Adisak Chatupheeraphat et al.   ORGANIC LETTERS

Synergistic Visible-Light Photoredox/Nickel-Catalyzed Synthesis of Aliphatic Ketones via N–C Cleavage of Imides

(2017) Javad Amani et al.   ORGANIC LETTERS

Ni-Catalyzed Reductive Cross-Coupling of Amides with Aryl Iodide Electrophiles via C–N Bond Activation

(2017) Shengyang Ni et al.   ORGANIC LETTERS

Amide to Alkyne Interconversion via a Nickel/Copper-Catalyzed Deamidative Cross-Coupling of Aryl and Alkenyl Amides

(2017) Watchara Srimontree et al.   ORGANIC LETTERS

Decarbonylative Cyanation of Amides by Palladium Catalysis

(2017) Shicheng Shi et al.   ORGANIC LETTERS

A General Method for Two-Step Transamidation of Secondary Amides Using Commercially Available, Air- and Moisture-Stable Palladium/NHC (N-Heterocyclic Carbene) Complexes

(2017) Guangrong Meng et al.   ORGANIC LETTERS

Metal-Free Transamidation of Secondary Amides via Selective N–C Cleavage under Mild Conditions

(2017) Yongmei Liu et al.   ORGANIC LETTERS

Ni-mediated C–N activation of amides and derived catalytic transformations

(2017) Yuan Gao et al.   Science China-Chemistry

Syntheses of Diverse Natural Products via Dual-Mode Lewis Acid Induced Cascade Cyclization Reactions

(2017) Chi-Sing Lee et al.   SYNLETT

Nickel-catalyzed transamidation of aliphatic amide derivatives

(2017) Jacob E. Dander et al.   Chemical Science

Nickel-Catalyzed Reductive Transamidation of Secondary Amides with Nitroarenes

(2017) Chi Wai Cheung et al.   ACS Catalysis

General Method for the Suzuki–Miyaura Cross-Coupling of Amides Using Commercially Available, Air- and Moisture-Stable Palladium/NHC (NHC = N-Heterocyclic Carbene) Complexes

(2017) Peng Lei et al.   ACS Catalysis

Synthesis of Biaryls through Nickel-Catalyzed Suzuki-Miyaura Coupling of Amides by Carbon-Nitrogen Bond Cleavage

(2016) Shicheng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sterically-controlled intermolecular Friedel–Crafts acylation with twisted amides via selective N–C cleavage under mild conditions

(2016) Yongmei Liu et al.   CHEMICAL COMMUNICATIONS

Nonclassical Routes for Amide Bond Formation

(2016) Renata Marcia de Figueiredo et al.   CHEMICAL REVIEWS

Efficient Synthesis of Diaryl Ketones by Nickel-Catalyzed Negishi Cross-Coupling of Amides by Carbon-Nitrogen Bond Cleavage at Room Temperature Accelerated by a Solvent Effect

(2016) Shicheng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structures of Highly Twisted Amides Relevant to Amide N−C Cross-Coupling: Evidence for Ground-State Amide Destabilization

(2016) Vittorio Pace et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Developments in Amide Synthesis Using Nonactivated Starting Materials

(2016) Andrea Ojeda-Porras et al.   JOURNAL OF ORGANIC CHEMISTRY

Ground-State Distortion in N-Acyl-tert-butyl-carbamates (Boc) and N-Acyl-tosylamides (Ts): Twisted Amides of Relevance to Amide N–C Cross-Coupling

(2016) Roman Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

Making the Least Reactive Electrophile the First in Class: Domino Electrophilic Activation of Amides

(2016) Daniel Kaiser et al.   JOURNAL OF ORGANIC CHEMISTRY

Practical Synthesis of Amides via Copper/ABNO-Catalyzed Aerobic Oxidative Coupling of Alcohols and Amines

(2016) Susan L. Zultanski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalyzed Suzuki–Miyaura coupling of amides by carbon–nitrogen cleavage: general strategy for amide N–C bond activation

(2016) Guangrong Meng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rhodium-Catalyzed C–H Bond Functionalization with Amides by Double C–H/C–N Bond Activation

(2016) Guangrong Meng et al.   ORGANIC LETTERS

Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals

(2016) Joshua R. Dunetz et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis

(2016) Emma L. Baker et al.   Nature Communications

Nickel-Catalyzed Deamidative Step-Down Reduction of Amides to Aromatic Hydrocarbons

(2016) Aniruddha Dey et al.   ACS Catalysis

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules

(2015) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General Olefin Synthesis by the Palladium-Catalyzed Heck Reaction of Amides: Sterically Controlled Chemoselective NC Activation

(2015) Guangrong Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic amidation of unactivated ester derivatives mediated by trifluoroethanol

(2015) Nicola Caldwell et al.   CHEMICAL COMMUNICATIONS

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

(2015) Dean G. Brown et al.   JOURNAL OF MEDICINAL CHEMISTRY

Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds

(2015) Liana Hie et al.   NATURE

Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides

(2015) Guangrong Meng et al.   ORGANIC LETTERS

A two-step, one pot preparation of amines via acyl succinimides. Synthesis of the calcimimetic agents cinacalcet, NPS R-467, and NPS R-568

(2015) Cassie A. Gooodman et al.   TETRAHEDRON LETTERS

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

l-Proline: An Efficient Catalyst for Transamidation of Carboxamides with Amines

(2013) Sadu Nageswara Rao et al.   ORGANIC LETTERS

Synthesis, X-Ray Crystallography, and Reactions ofN-Acyl andN-Carbamoyl Succinimides

(2013) Cassie A. Goodman et al.   SYNTHETIC COMMUNICATIONS

Synthesis and evaluation of some variants of the Nefkens’ reagent

(2013) Cassie A. Goodman et al.   TETRAHEDRON LETTERS

Microwave-Assisted Deacylation of Unactivated Amides Using Ammonium-Salt-Accelerated Transamidation

(2012) Yuhei Shimizu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Twist on Amide Solvolysis

(2012) Jeffrey Aubé   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Acyl DBN Tetraphenylborate Salts as N-Acylating Agents

(2012) James E. Taylor et al.   JOURNAL OF ORGANIC CHEMISTRY

Chemoselective synthesis of ketones and ketimines by addition of organometallic reagents to secondary amides

(2012) William S. Bechara et al.   Nature Chemistry

Boric Acid: A Highly Efficient Catalyst for Transamidation of Carboxamides with Amines

(2012) Thanh Binh Nguyen et al.   ORGANIC LETTERS

Transamidation of Primary Amides with Amines Using Hydroxylamine Hydrochloride as an Inorganic Catalyst

(2011) C. Liana Allen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-catalysed approaches to amide bond formation

(2011) C. Liana Allen et al.   CHEMICAL SOCIETY REVIEWS

The Medicinal Chemist’s Toolbox: An Analysis of Reactions Used in the Pursuit of Drug Candidates

(2011) Stephen D. Roughley et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rethinking amide bond synthesis

(2011) Vijaya R. Pattabiraman et al.   NATURE

Zinc-Catalyzed Reduction of Amides: Unprecedented Selectivity and Functional Group Tolerance

(2010) Shoubhik Das et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The pKBHXDatabase: Toward a Better Understanding of Hydrogen-Bond Basicity for Medicinal Chemists

(2009) Christian Laurence et al.   JOURNAL OF MEDICINAL CHEMISTRY

Catalytic Transamidation Reactions Compatible with Tertiary Amide Metathesis under Ambient Conditions

(2009) Nickeisha A. Stephenson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amide bond formation: beyond the myth of coupling reagents

(2008) Eric Valeur et al.   CHEMICAL SOCIETY REVIEWS

Enzyme-Like Chemoselective Acylation of Alcohols in the Presence of Amines Catalyzed by a Tetranuclear Zinc Cluster

(2008) Takashi Ohshima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY