Structures of Highly Twisted Amides Relevant to Amide N−C Cross-Coupling: Evidence for Ground-State Amide Destabilization

Structural Characterization of N-Alkylated Twisted Amides: Consequences for Amide Bond Resonance and N−C Cleavage

(2016) Feng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Biaryls through Nickel-Catalyzed Suzuki-Miyaura Coupling of Amides by Carbon-Nitrogen Bond Cleavage

(2016) Shicheng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Decarbonylative Borylation of Amides: Evidence for Acyl C−N Bond Activation

(2016) Jiefeng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sterically-controlled intermolecular Friedel–Crafts acylation with twisted amides via selective N–C cleavage under mild conditions

(2016) Yongmei Liu et al.   CHEMICAL COMMUNICATIONS

Efficient Synthesis of Diaryl Ketones by Nickel-Catalyzed Negishi Cross-Coupling of Amides by Carbon-Nitrogen Bond Cleavage at Room Temperature Accelerated by a Solvent Effect

(2016) Shicheng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis and Characterization of 7-Hypoquinuclidonium Tetrafluoroborate and 7-Hypoquinuclidone BF3 Complex

(2016) Marc Liniger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-catalyzed Suzuki–Miyaura coupling of amides by carbon–nitrogen cleavage: general strategy for amide N–C bond activation

(2016) Guangrong Meng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rhodium-Catalyzed C–H Bond Functionalization with Amides by Double C–H/C–N Bond Activation

(2016) Guangrong Meng et al.   ORGANIC LETTERS

Benchtop Delivery of Ni(cod)2 using Paraffin Capsules

(2016) Jacob E. Dander et al.   ORGANIC LETTERS

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis

(2016) Emma L. Baker et al.   Nature Communications

Nickel-Catalyzed Alkylation of Amide Derivatives

(2016) Bryan J. Simmons et al.   ACS Catalysis

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules

(2015) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General Olefin Synthesis by the Palladium-Catalyzed Heck Reaction of Amides: Sterically Controlled Chemoselective NC Activation

(2015) Guangrong Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An efficient computational model to predict protonation at the amide nitrogen and reactivity along the C–N rotational pathway

(2015) Roman Szostak et al.   CHEMICAL COMMUNICATIONS

Acylative Suzuki coupling of amides: acyl-nitrogen activation via synergy of independently modifiable activating groups

(2015) Xijing Li et al.   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed Cleavage of C–N Single Bonds

(2015) Kunbing Ouyang et al.   CHEMICAL REVIEWS

Determination of Structures and Energetics of Small- and Medium-Sized One-Carbon-Bridged Twisted Amides using ab Initio Molecular Orbital Methods: Implications for Amidic Resonance along the C–N Rotational Pathway

(2015) Roman Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

The Most Reactive Amide As a Transition-State Mimic For cis–trans Interconversion

(2015) Igor V. Komarov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds

(2015) Liana Hie et al.   NATURE

Nickel-catalysed Suzuki–Miyaura coupling of amides

(2015) Nicholas A. Weires et al.   Nature Chemistry

Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides

(2015) Guangrong Meng et al.   ORGANIC LETTERS

Novel bridgehead bicyclic lactams: (a) Molecules predicted to have O-protonated and N-protonated tautomers of comparable stability; (b) hyperstable lactams and their O-protonated tautomers

(2014) Jessica Morgan et al.   JOURNAL OF CHEMICAL THERMODYNAMICS

Chemistry of Bridged Lactams and Related Heterocycles

(2013) Michal Szostak et al.   CHEMICAL REVIEWS

Electrospray Ionization (ESI) Fragmentations and Dimethyldioxirane Reactivities of Three Diverse Lactams Having Full, Half, and Zero Resonance Energies

(2013) Kathleen M. Morgan et al.   JOURNAL OF ORGANIC CHEMISTRY

A New Twist on Amide Solvolysis

(2012) Jeffrey Aubé   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reliable Determination of Amidicity in Acyclic Amides and Lactams

(2012) Stephen A. Glover et al.   JOURNAL OF ORGANIC CHEMISTRY

N-protonated andO-protonated tautomers of 1-azabicyclo[3.3.1]nonan-2-one: observation of individual13C-NMR carbonyl peaks and comparisons with protonated tautomers of planar and other distorted lactams

(2012) Jessica Morgan et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

Switching Pathways: Room-Temperature Neutral Solvolysis and Substitution of Amides

(2011) Marc Hutchby et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acid-Catalyzed Reactions of Twisted Amides in Water Solution: Competition between Hydration and Hydrolysis

(2011) Binju Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

1-Azabicyclo[3.3.1]nonan-2-one: Nitrogen Versus Oxygen Protonation

(2011) Brian Sliter et al.   JOURNAL OF ORGANIC CHEMISTRY

Paradigms and paradoxes: O- and N-protonated amides, stabilization energy, and resonance energy

(2011) Jessica Morgan et al.   STRUCTURAL CHEMISTRY

Water-Stable Helical Structure of Tertiary Amides of Bicyclic β-Amino Acid Bearing 7-Azabicyclo[2.2.1]heptane. Full Control of Amide Cis−Trans Equilibrium by Bridgehead Substitution

(2010) Masahiro Hosoya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Characterization of N-Protonated Amides: Regioselective N-Activation of Medium-Bridged Twisted Lactams

(2010) Michal Szostak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein Autoproteolysis: Conformational Strain Linked to the Rate of Peptide Cleavage by the pH Dependence of the N → O Acyl Shift Reaction

(2009) Denny G. A. Johansson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quasiplanarity of the Peptide Bond

(2008) Jakub Chalupský et al.   JOURNAL OF PHYSICAL CHEMISTRY A