Nickel-catalyzed transamidation of aliphatic amide derivatives

Resonance Destabilization in N-Acylanilines (Anilides): Electronically-Activated Planar Amides of Relevance in N–C(O) Cross-Coupling

(2017) Roman Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

A General Method for Two-Step Transamidation of Secondary Amides Using Commercially Available, Air- and Moisture-Stable Palladium/NHC (N-Heterocyclic Carbene) Complexes

(2017) Guangrong Meng et al.   ORGANIC LETTERS

Metal-Free Transamidation of Secondary Amides via Selective N–C Cleavage under Mild Conditions

(2017) Yongmei Liu et al.   ORGANIC LETTERS

General Method for the Suzuki–Miyaura Cross-Coupling of Amides Using Commercially Available, Air- and Moisture-Stable Palladium/NHC (NHC = N-Heterocyclic Carbene) Complexes

(2017) Peng Lei et al.   ACS Catalysis

Breaking Amides using Nickel Catalysis

(2017) Jacob E. Dander et al.   ACS Catalysis

Suzuki Coupling of AmidesviaPalladium-Catalyzed C-N Cleavage ofN-Acylsaccharins

(2016) Hongxiang Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Nickel-Catalyzed Esterification of Aliphatic Amides

(2016) Liana Hie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Biaryls through Nickel-Catalyzed Suzuki-Miyaura Coupling of Amides by Carbon-Nitrogen Bond Cleavage

(2016) Shicheng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Decarbonylative Borylation of Amides: Evidence for Acyl C−N Bond Activation

(2016) Jiefeng Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalyzed Sonogashira coupling of amides: access to ynones via C–N bond cleavage

(2016) Ming Cui et al.   CHEMICAL COMMUNICATIONS

Nonclassical Routes for Amide Bond Formation

(2016) Renata Marcia de Figueiredo et al.   CHEMICAL REVIEWS

Efficient Synthesis of Diaryl Ketones by Nickel-Catalyzed Negishi Cross-Coupling of Amides by Carbon-Nitrogen Bond Cleavage at Room Temperature Accelerated by a Solvent Effect

(2016) Shicheng Shi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structures of Highly Twisted Amides Relevant to Amide N−C Cross-Coupling: Evidence for Ground-State Amide Destabilization

(2016) Vittorio Pace et al.   CHEMISTRY-A EUROPEAN JOURNAL

Recent Developments in Amide Synthesis Using Nonactivated Starting Materials

(2016) Andrea Ojeda-Porras et al.   JOURNAL OF ORGANIC CHEMISTRY

Ground-State Distortion in N-Acyl-tert-butyl-carbamates (Boc) and N-Acyl-tosylamides (Ts): Twisted Amides of Relevance to Amide N–C Cross-Coupling

(2016) Roman Szostak et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Acylsaccharins as Amide-Based Arylating Reagents via Chemoselective N–C Cleavage: Pd-Catalyzed Decarbonylative Heck Reaction

(2016) Chengwei Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-catalyzed Suzuki–Miyaura coupling of amides by carbon–nitrogen cleavage: general strategy for amide N–C bond activation

(2016) Guangrong Meng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-Acylsaccharins: Stable Electrophilic Amide-Based Acyl Transfer Reagents in Pd-Catalyzed Suzuki–Miyaura Coupling via N–C Cleavage

(2016) Chengwei Liu et al.   ORGANIC LETTERS

Nickel-Catalyzed Diaryl Ketone Synthesis by N–C Cleavage: Direct Negishi Cross-Coupling of Primary Amides by Site-Selective N,N-Di-Boc Activation

(2016) Shicheng Shi et al.   ORGANIC LETTERS

Rhodium-Catalyzed C–H Bond Functionalization with Amides by Double C–H/C–N Bond Activation

(2016) Guangrong Meng et al.   ORGANIC LETTERS

Benchtop Delivery of Ni(cod)2 using Paraffin Capsules

(2016) Jacob E. Dander et al.   ORGANIC LETTERS

Cross-Coupling of Amides by N–C Bond Activation

(2016) Michal Szostak et al.   SYNLETT

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis

(2016) Emma L. Baker et al.   Nature Communications

Nickel-Catalyzed Alkylation of Amide Derivatives

(2016) Bryan J. Simmons et al.   ACS Catalysis

Palladium-Catalyzed Suzuki–Miyaura Cross-Coupling of Amides via Site-Selective N–C Bond Cleavage by Cooperative Catalysis

(2016) Guangrong Meng et al.   ACS Catalysis

Nickel-Catalyzed Deamidative Step-Down Reduction of Amides to Aromatic Hydrocarbons

(2016) Aniruddha Dey et al.   ACS Catalysis

General Olefin Synthesis by the Palladium-Catalyzed Heck Reaction of Amides: Sterically Controlled Chemoselective NC Activation

(2015) Guangrong Meng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An efficient computational model to predict protonation at the amide nitrogen and reactivity along the C–N rotational pathway

(2015) Roman Szostak et al.   CHEMICAL COMMUNICATIONS

Acylative Suzuki coupling of amides: acyl-nitrogen activation via synergy of independently modifiable activating groups

(2015) Xijing Li et al.   CHEMICAL COMMUNICATIONS

Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds

(2015) Liana Hie et al.   NATURE

Nickel-catalysed Suzuki–Miyaura coupling of amides

(2015) Nicholas A. Weires et al.   Nature Chemistry

Sterically Controlled Pd-Catalyzed Chemoselective Ketone Synthesis via N–C Cleavage in Twisted Amides

(2015) Guangrong Meng et al.   ORGANIC LETTERS

Clean and efficient assembly of functionalized benzofuro[2,3-c]pyridines via metal-free one-pot domino reactions

(2014) Yin Rao et al.   GREEN CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Transamidation of Carboxamides Catalyzed by Fe(III) and Water

(2014) Liliana Becerra-Figueroa et al.   JOURNAL OF ORGANIC CHEMISTRY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

l-Proline: An Efficient Catalyst for Transamidation of Carboxamides with Amines

(2013) Sadu Nageswara Rao et al.   ORGANIC LETTERS

Heterocycles in drugs and drug discovery

(2012) A. Gomtsyan   Chemistry of Heterocyclic Compounds

Ni- and Fe-Catalyzed Cross-Coupling Reactions of Phenol Derivatives

(2012) Tehetena Mesganaw et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Transamidation of Primary Amides with Amines Using Hydroxylamine Hydrochloride as an Inorganic Catalyst

(2011) C. Liana Allen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rethinking amide bond synthesis

(2011) Vijaya R. Pattabiraman et al.   NATURE

Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds

(2010) Brad M. Rosen et al.   CHEMICAL REVIEWS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Amidicity Change as a Significant Driving Force and Thermodynamic Selection Rule of Transamidation Reactions. A Synergy between Experiment and Theory

(2008) Zoltán Mucsi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

(2008) Kenneth L. Kirk   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS