Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Unrivalled diversity: the many roles and reactions of bacterial cytochromes P450 in secondary metabolism
Authors
Keywords
-
Journal
NATURAL PRODUCT REPORTS
Volume -, Issue -, Pages -
Publisher
Royal Society of Chemistry (RSC)
Online
2018-04-18
DOI
10.1039/c7np00063d
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cytochrome P450 diversity in the tree of life
- (2018) David R. Nelson BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- A route to diastereomerically pure phenylglycine thioester peptides: crucial intermediates for investigating glycopeptide antibiotic biosynthesis
- (2018) Julien Tailhades et al. CHEMICAL COMMUNICATIONS
- Oximes: Unrecognized Chameleons in General and Specialized Plant Metabolism
- (2018) Mette Sørensen et al. Molecular Plant
- Structural analysis of SgvP involved in carbon-sulfur bond formation during griseoviridin biosynthesis
- (2017) Qin Li et al. FEBS LETTERS
- Production of alkenes and novel secondary products by P450 OleTJE using novel H2 O2 -generating fusion protein systems
- (2017) Sarah Matthews et al. FEBS LETTERS
- Isolation and characterization ofRhizobiumsp. strain YS-1r that degrades lignin in plant biomass
- (2017) C.A. Jackson et al. JOURNAL OF APPLIED MICROBIOLOGY
- Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 fromMycobacterium tuberculosisproceeds through a catalytic shunt pathway
- (2017) Kednerlin Dornevil et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and characterization of a bacterial cytochrome P450 monooxygenase catalyzing the 3-nitration of tyrosine in rufomycin biosynthesis
- (2017) Hiroya Tomita et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE
- (2017) Sarah Matthews et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diversity of nature's assembly lines – recent discoveries in non-ribosomal peptide synthesis
- (2017) Jennifer A. E. Payne et al. Molecular BioSystems
- Expansion of chemical space for natural products by uncommon P450 reactions
- (2017) Xingwang Zhang et al. NATURAL PRODUCT REPORTS
- Cytochromes P450 for natural product biosynthesis in Streptomyces: sequence, structure, and function
- (2017) Jeffrey D. Rudolf et al. NATURAL PRODUCT REPORTS
- Post-translational modifications involved in the biosynthesis of thiopeptide antibiotics
- (2017) Qingfei Zheng et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Characterization of a novel CYP51 from Rhodococcus triatomae and its NADH-ferredoxin reductase-coupled application in lanosterol 14α-demethylation
- (2017) Xia Ke et al. PROCESS BIOCHEMISTRY
- P450 catalysed dehydrogenation
- (2017) Siew Hoon Wong et al. PURE AND APPLIED CHEMISTRY
- Nonomuraea sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster
- (2017) Behnam Nazari et al. MedChemComm
- P450 monooxygenase ComJ catalyses side chain phenolic cross-coupling during complestatin biosynthesis
- (2017) Aurelio Mollo et al. RSC Advances
- Mutagenesis and redox partners analysis of the P450 fatty acid decarboxylase OleTJE
- (2017) Bo Fang et al. Scientific Reports
- Precursor-Directed Mutational Biosynthesis Facilitates the Functional Assignment of Two Cytochromes P450 in Thiostrepton Biosynthesis
- (2016) Qingfei Zheng et al. ACS Chemical Biology
- Probing the selectivity of β-hydroxylation reactions in non-ribosomal peptide synthesis using analytical ultracentrifugation
- (2016) Bashkim Kokona et al. ANALYTICAL BIOCHEMISTRY
- Dissecting Bottromycin Biosynthesis Using Comparative Untargeted Metabolomics
- (2016) William J. K. Crone et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- CYP101J2, CYP101J3, and CYP101J4, 1,8-Cineole-Hydroxylating Cytochrome P450 Monooxygenases from Sphingobium yanoikuyae Strain B2
- (2016) Birgit Unterweger et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Biochemical and structural characterisation of the second oxidative crosslinking step during the biosynthesis of the glycopeptide antibiotic A47934
- (2016) Veronika Ulrich et al. Beilstein Journal of Organic Chemistry
- Parallel Post-Polyketide Synthase Modification Mechanism Involved in FD-891 Biosynthesis inStreptomyces graminofaciensA-8890
- (2016) Fumitaka Kudo et al. CHEMBIOCHEM
- Generation of New Complestatin Analogues by Heterologous Expression of the Complestatin Biosynthetic Gene Cluster fromStreptomyces chartreusisAN1542
- (2016) Ok-Kyung Park et al. CHEMBIOCHEM
- Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis
- (2016) Madeleine Peschke et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Cholesterol Analogs with Degradation-resistant Alkyl Side Chains Are EffectiveMycobacterium tuberculosisGrowth Inhibitors
- (2016) Daniel J. Frank et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biosynthetic Timing and Substrate Specificity for the Thiopeptide Thiomuracin
- (2016) Zhengan Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Flavin-Dependent Decarboxylase–Dehydrogenase–Monooxygenase Assembles the Warhead of α,β-Epoxyketone Proteasome Inhibitors
- (2016) Daniel Zabala et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis
- (2016) Madeleine Peschke et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism
- (2016) Lian Duan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids
- (2016) Christian Görner et al. Microbial Cell Factories
- More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH
- (2016) Veronika Ulrich et al. Molecular BioSystems
- Bacterial terpene cyclases
- (2016) Jeroen S. Dickschat NATURAL PRODUCT REPORTS
- Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution
- (2016) Ryan S Nett et al. Nature Chemical Biology
- Catalytic strategy for carbon−carbon bond scission by the cytochrome P450 OleT
- (2016) Job L. Grant et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A genomics-led approach to deciphering the mechanism of thiotetronate antibiotic biosynthesis
- (2016) W. Tao et al. Chemical Science
- Redox Partner Interaction Sites in Cytochrome P450 Monooxygenases:In SilicoAnalysis and Experimental Validation
- (2016) Łukasz Gricman et al. ChemistrySelect
- F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE
- (2016) Madeleine Peschke et al. Scientific Reports
- A Peptidyl-Transesterifying Type I Thioesterase in Salinamide Biosynthesis
- (2015) Lauren Ray et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis
- (2015) Clara Brieke et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Single Enzyme Transforms a Carboxylic Acid into a Nitrile through an Amide Intermediate
- (2015) Micah T. Nelp et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- CYP287A1 is a carotenoid 2-β-hydroxylase required for deinoxanthin biosynthesis in Deinococcus radiodurans R1
- (2015) Zhengfu Zhou et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Characterization of the Nocardiopsin Biosynthetic Gene Cluster Reveals Similarities to and Differences from the Rapamycin and FK-506 Pathways
- (2015) Dana M. Bis et al. CHEMBIOCHEM
- Biosynthesis of Neocarazostatin A Reveals the Sequential Carbazole Prenylation and Hydroxylation in the Tailoring Steps
- (2015) Sheng Huang et al. CHEMISTRY & BIOLOGY
- A Subdomain Swap Strategy for Reengineering Nonribosomal Peptides
- (2015) Hajo Kries et al. CHEMISTRY & BIOLOGY
- Biosynthetic Studies of Telomycin Reveal New Lipopeptides with Enhanced Activity
- (2015) Chengzhang Fu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In Vitro Biosynthesis of the Core Scaffold of the Thiopeptide Thiomuracin
- (2015) Graham A. Hudson et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Decarboxylation of Fatty Acids to Terminal Alkenes by Cytochrome P450 Compound I
- (2015) Job L. Grant et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Generation of the natamycin analogs by gene engineering of natamycin biosynthetic genes in Streptomyces chattanoogensis L10
- (2015) Shui-Ping Liu et al. MICROBIOLOGICAL RESEARCH
- Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products
- (2015) Rashed S. Al Toma et al. NATURAL PRODUCT REPORTS
- X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis
- (2015) Kristina Haslinger et al. NATURE
- β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis
- (2015) Nicole M. Gaudelli et al. NATURE
- Synergism between genome sequencing, tandem mass spectrometry and bio-inspired synthesis reveals insights into nocardioazine B biogenesis
- (2015) Norah Alqahtani et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics
- (2015) Clara Brieke et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis
- (2015) Kristina Haslinger et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Reprogramming Nonribosomal Peptide Synthetases for “Clickable” Amino Acids
- (2014) Hajo Kries et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The Structure of a Transient Complex of a Nonribosomal Peptide Synthetase and a Cytochrome P450 Monooxygenase
- (2014) Kristina Haslinger et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hydrogen peroxide-independent production of α-alkenes by OleTJE P450 fatty acid decarboxylase
- (2014) Yi Liu et al. Biotechnology for Biofuels
- Cytochrome P450 OxyBteiCatalyzes the First Phenolic Coupling Step in Teicoplanin Biosynthesis
- (2014) Kristina Haslinger et al. CHEMBIOCHEM
- Involvement of SgvP in Carbon-Sulfur Bond Formation during Griseoviridin Biosynthesis
- (2014) Yunchang Xie et al. CHEMBIOCHEM
- Structural, Functional, and Spectroscopic Characterization of the Substrate Scope of the Novel Nitrating Cytochrome P450 TxtE
- (2014) Sheel C. Dodani et al. CHEMBIOCHEM
- Biosynthesis of the 4-Methyloxazoline-Containing Nonribosomal Peptides, JBIR-34 and -35, in Streptomyces sp. Sp080513GE-23
- (2014) Adeline Muliandi et al. CHEMISTRY & BIOLOGY
- Stereochemistry and Conformation of Skyllamycin, a Non-Ribosomally Synthesized Peptide fromStreptomycessp. Acta 2897
- (2014) Vivien Schubert et al. CHEMISTRY-A EUROPEAN JOURNAL
- CYP105-diverse structures, functions and roles in an intriguing family of enzymes inStreptomyces
- (2014) Suzy C. Moody et al. JOURNAL OF APPLIED MICROBIOLOGY
- Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE(CYP152L1) from theJeotgalicoccussp. 8456 Bacterium
- (2014) James Belcher et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Borrelidin B: Isolation, Biological Activity, and Implications for Nitrile Biosynthesis
- (2014) Christopher J. Schulze et al. JOURNAL OF NATURAL PRODUCTS
- Characterization of an Orphan Diterpenoid Biosynthetic Operon from Salinispora arenicola
- (2014) Meimei Xu et al. JOURNAL OF NATURAL PRODUCTS
- Epimerization and substrate gating by a TE domain in β-lactam antibiotic biosynthesis
- (2014) Nicole M Gaudelli et al. Nature Chemical Biology
- Terpene synthases are widely distributed in bacteria
- (2014) Yuuki Yamada et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genetic Basis for the Biosynthesis of the Pharmaceutically Important Class of Epoxyketone Proteasome Inhibitors
- (2013) Michelle Schorn et al. ACS Chemical Biology
- Cytochrome P450sky Interacts Directly with the Nonribosomal Peptide Synthetase to Generate Three Amino Acid Precursors in Skyllamycin Biosynthesis
- (2013) Stefanie Uhlmann et al. ACS Chemical Biology
- Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds
- (2013) Christopher T. Walsh et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tentative biosynthetic pathways of some microbial diketopiperazines
- (2013) Binbin Gu et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- CYP261 enzymes from deep sea bacteria: A clue to conformational heterogeneity in cytochromes P450
- (2013) Dmitri R. Davydov et al. BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY
- Cloning and Heterologous Expression of the Aurachin RE Biosynthesis Gene Cluster Afford a New Cytochrome P450 for Quinoline N-Hydroxylation
- (2013) Wataru Kitagawa et al. CHEMBIOCHEM
- Structural analysis of HmtT and HmtN involved in the tailoring steps of himastatin biosynthesis
- (2013) Huaidong Zhang et al. FEBS LETTERS
- Structure of the quinoline N-hydroxylating cytochrome P450 RauA, an essential enzyme that confers antibiotic activity on aurachin alkaloids
- (2013) Yoshiaki Yasutake et al. FEBS LETTERS
- Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis
- (2013) Lijiang Song et al. JOURNAL OF ANTIBIOTICS
- Glycopeptide antibiotic biosynthesis
- (2013) Grace Yim et al. JOURNAL OF ANTIBIOTICS
- Substrate and Reaction Specificity ofMycobacterium tuberculosisCytochrome P450 CYP121
- (2013) Matthieu Fonvielle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unusual Cytochrome P450 Enzymes and Reactions
- (2013) F. Peter Guengerich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus
- (2013) Xiaoling Wang et al. Molecular BioSystems
- In Vitro Characterization of Echinomycin Biosynthesis: Formation and Hydroxylation of L-Tryptophanyl-S-Enzyme and Oxidation of (2S,3S) β-Hydroxytryptophan
- (2013) Chen Zhang et al. PLoS One
- Structural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtE
- (2013) Feng Yu et al. PLoS One
- QM/MM study of the C-C coupling reaction mechanism of CYP121, an essential Cytochrome p450 ofMycobacterium tuberculosis
- (2013) Victoria G. Dumas et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Iron(IV)hydroxide pKa and the Role of Thiolate Ligation in C-H Bond Activation by Cytochrome P450
- (2013) T. H. Yosca et al. SCIENCE
- Substituent Effects on the Phenol Coupling Reaction Catalyzed by the Vancomycin Biosynthetic P450 Enzyme OxyB
- (2012) Patrick C. Schmartz et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Biosynthesis of new lipopentapeptides by an engineered strain of Streptomyces sp.
- (2012) Xu Jin et al. BIOTECHNOLOGY LETTERS
- Pyran Formation by an Atypical CYP-Mediated Four-Electron Oxygenation-Cyclization Cascade in an Engineered Aureothin Pathway
- (2012) Martin Richter et al. CHEMBIOCHEM
- Identification of the Biosynthetic Gene Cluster and Regulatory Cascade for the Synergistic Antibacterial Antibiotics Griseoviridin and Viridogrisein inStreptomyces griseoviridis
- (2012) Yunchang Xie et al. CHEMBIOCHEM
- Bacterial CYP153A monooxygenases for the synthesis of omega-hydroxylated fatty acids
- (2012) Sumire Honda Malca et al. CHEMICAL COMMUNICATIONS
- An Unusual Role for a Mobile Flavin in StaC-like Indolocarbazole Biosynthetic Enzymes
- (2012) Peter J. Goldman et al. CHEMISTRY & BIOLOGY
- Biosynthesis of the Respiratory Toxin Bongkrekic Acid in the Pathogenic Bacterium Burkholderia gladioli
- (2012) Nadine Moebius et al. CHEMISTRY & BIOLOGY
- Synthetic Biotechnology to Study and Engineer Ribosomal Bottromycin Biosynthesis
- (2012) Liujie Huo et al. CHEMISTRY & BIOLOGY
- Enzyme-Substrate Complementarity Governs Access to a Cationic Reaction Manifold in the P450BM3-Catalysed Oxidation of Cyclopropyl Fatty Acids
- (2012) Max J. Cryle et al. CHEMISTRY-A EUROPEAN JOURNAL
- Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology
- (2012) Gene H. Hur et al. NATURAL PRODUCT REPORTS
- Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
- (2012) Paul G. Arnison et al. NATURAL PRODUCT REPORTS
- Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis
- (2012) Sarah M Barry et al. Nature Chemical Biology
- Posttranslational β-methylation and macrolactamidination in the biosynthesis of the bottromycin complex of ribosomal peptide antibiotics
- (2012) Juan Pablo Gomez-Escribano et al. Chemical Science
- Identification and characterisation of the gene cluster for the anti-MRSA antibiotic bottromycin: expanding the biosynthetic diversity of ribosomal peptides
- (2012) William J. K. Crone et al. Chemical Science
- Biosynthesis of Himastatin: Assembly Line and Characterization of Three Cytochrome P450 Enzymes Involved in the Post-tailoring Oxidative Steps
- (2011) Junying Ma et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Efficient functional analysis system for cyanobacterial or plant cytochromes P450 involved in sesquiterpene biosynthesis
- (2011) Hisashi Harada et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- P450BM3(CYP102A1): connecting the dots
- (2011) Christopher J. C. Whitehouse et al. CHEMICAL SOCIETY REVIEWS
- Genome Mining in Streptomyces clavuligerus: Expression and Biochemical Characterization of Two New Cryptic Sesquiterpene Synthases
- (2011) Yunfeng Hu et al. CHEMISTRY & BIOLOGY
- Crystal Structure of H2O2-dependent Cytochrome P450SPαwith Its Bound Fatty Acid Substrate
- (2011) Takashi Fujishiro et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structure of the Glycosyltransferase EryCIII in Complex with its Activating P450 Homologue EryCII
- (2011) Martin C. Moncrieffe et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural Fine-Tuning of a Multifunctional Cytochrome P450 Monooxygenase
- (2011) Georg Zocher et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Genome Mining inStreptomyces. Discovery of an Unprecedented P450-Catalyzed Oxidative Rearrangement That Is the Final Step in the Biosynthesis of Pentalenolactone
- (2011) Dongqing Zhu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Imaging Mass Spectrometry and Genome Mining via Short Sequence Tagging Identified the Anti-Infective Agent Arylomycin inStreptomyces roseosporus
- (2011) Wei-Ting Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biosynthetic Gene Cluster of the Non-ribosomally Synthesized Cyclodepsipeptide Skyllamycin: Deciphering Unprecedented Ways of Unusual Hydroxylation Reactions
- (2011) Stefan Pohle et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Carrier protein substrates in cytochrome P450-catalysed oxidation
- (2011) Max J. Cryle Metallomics
- Completing the puzzle of aurachin biosynthesis in Stigmatella aurantiaca Sg a15
- (2011) Dominik Pistorius et al. Molecular BioSystems
- Tirandamycin biosynthesis is mediated by co-dependent oxidative enzymes
- (2011) Jacob C. Carlson et al. Nature Chemistry
- Regioselective ω-hydroxylation of medium-chain n-alkanes and primary alcohols by CYP153 enzymes from Mycobacterium marinum and Polaromonas sp. strain JS666
- (2011) Daniel Scheps et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Nocardioazines: A Novel Bridged Diketopiperazine Scaffold from a Marine-Derived Bacterium Inhibits P-Glycoprotein
- (2011) Ritesh Raju et al. ORGANIC LETTERS
- Identification of the thiazolyl peptide GE37468 gene cluster fromStreptomycesATCC 55365 and heterologous expression inStreptomyces lividans
- (2011) Travis S. Young et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
- (2011) L. Laureti et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: Implications for the mechanism of electron transfer in the P450 BM3 dimer
- (2010) Hazel M. Girvan et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Selectivity in a barren landscape: the P450BioI–ACP complex
- (2010) Max J. Cryle BIOCHEMICAL SOCIETY TRANSACTIONS
- Cytochrome P450 fromPhotobacterium profundumSS9, a Piezophilic Bacterium, Exhibits a Tightened Control of Water Access to the Active Site
- (2010) Elena V. Sineva et al. BIOCHEMISTRY
- Structural and Biochemical Characterization of the Cytochrome P450 CypX (CYP134A1) fromBacillus subtilis: A Cyclo-l-leucyl-l-leucyl Dipeptide Oxidase
- (2010) Max J. Cryle et al. BIOCHEMISTRY
- Functions of Genes and Enzymes Involved in Phenalinolactone Biosynthesis
- (2010) Martina Daum et al. CHEMBIOCHEM
- The Thioesterase Bhp is Involved in the Formation of β-Hydroxytyrosine during Balhimycin Biosynthesis in Amycolatopsis balhimycina
- (2010) Sri Mulyani et al. CHEMBIOCHEM
- Oxidative Biotransformation of Fatty Acids by Cytochromes P450: Predicted Key Structural Elements Orchestrating Substrate Specificity, Regioselectivity and Catalytic Efficiency
- (2010) Peter Hlavica et al. CURRENT DRUG METABOLISM
- Glycopeptide biosynthesis in the context of basic cellular functions
- (2010) Evi Stegmann et al. CURRENT OPINION IN MICROBIOLOGY
- Genome mining inAmycolatopsis balhimycinafor ferredoxins capable of supporting cytochrome P450 enzymes involved in glycopeptide antibiotic biosynthesis
- (2010) Nina Geib et al. FEMS MICROBIOLOGY LETTERS
- Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics
- (2010) Yuki Hirose et al. JOURNAL OF ANTIBIOTICS
- Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis
- (2010) Satoshi Takamatsu et al. JOURNAL OF ANTIBIOTICS
- Functional Redundancy of Steroid C26-monooxygenase Activity inMycobacterium tuberculosisRevealed by Biochemical and Genetic Analyses
- (2010) Jonathan B. Johnston et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Characterization of OxyD, a Cytochrome P450 Involved in β-Hydroxytyrosine Formation in Vancomycin Biosynthesis
- (2010) Max J. Cryle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biosynthesis of 3-methoxy-5-methyl naphthoic acid and its incorporation into the antitumor antibiotic azinomycin B
- (2010) Wei Ding et al. Molecular BioSystems
- Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes
- (2010) L. C. Foulston et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics
- (2010) J. Rittle et al. SCIENCE
- Prediction and analysis of the modular structure of cytochrome P450 monooxygenases
- (2010) Demet Sirim et al. BMC STRUCTURAL BIOLOGY
- Tailoring the P450 Monooxygenase Gene for FR-008/Candicidin Biosynthesis
- (2009) S. Chen et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- A cytochrome P450 class I electron transfer system from Novosphingobium aromaticivorans
- (2009) Stephen G. Bell et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- The Cytochrome P450 Engineering Database: integration of biochemical properties
- (2009) Demet Sirim et al. BMC BIOCHEMISTRY
- P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations
- (2009) Sason Shaik et al. CHEMICAL REVIEWS
- Cloning and Heterologous Expression of the Cyclooctatin Biosynthetic Gene Cluster Afford a Diterpene Cyclase and Two P450 Hydroxylases
- (2009) Seung-Young Kim et al. CHEMISTRY & BIOLOGY
- Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site
- (2009) Bin Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enzymatic Production of (−)-Indolactam V by LtxB, a Cytochrome P450 Monooxygenase
- (2009) Minh U. Huynh et al. JOURNAL OF NATURAL PRODUCTS
- Theoretical and Experimental Studies of the Conversion of Chromopyrrolic Acid to an Antitumor Derivative by Cytochrome P450 StaP: The Catalytic Role of Water Molecules
- (2009) Yong Wang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Biochemical and structural characterization of CYP124: A methyl-branched lipid -hydroxylase from Mycobacterium tuberculosis
- (2009) J. B. Johnston et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis
- (2009) P. Belin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequential Asymmetric Polyketide Heterocyclization Catalyzed by a Single Cytochrome P450 Monooxygenase (AurH)
- (2008) Martin E. A. Richter et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Characterization of the Azinomycin B Biosynthetic Gene Cluster Revealing a Different Iterative Type I Polyketide Synthase for Naphthoate Biosynthesis
- (2008) Qunfei Zhao et al. CHEMISTRY & BIOLOGY
- Functional Analysis of MycCI and MycG, Cytochrome P450 Enzymes Involved in Biosynthesis of Mycinamicin Macrolide Antibiotics
- (2008) Yojiro Anzai et al. CHEMISTRY & BIOLOGY
- Identification of Sesquiterpene Synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. Strain PCC 7120
- (2008) S. A. Agger et al. JOURNAL OF BACTERIOLOGY
- Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone inStreptomyces coelicolorA3(2)
- (2008) Bin Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of Active Site Structure in CYP121
- (2008) Kirsty J. McLean et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The biosyntheticgene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892
- (2008) Ute Galm et al. Molecular BioSystems
- Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450BioI ACP complex
- (2008) M. J. Cryle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway
- (2008) Jason G. McCoy et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- The Role of the Conserved Threonine in P450BM3 Oxygen Activation: Substrate-Determined Hydroxylation Activity of the Thr268Ala Mutant
- (2007) Max J. Cryle et al. CHEMBIOCHEM
- Characterization of the Peroxidase Activity of CYP119, a Thermostable P450 FromSulfolobus acidocaldarius
- (2007) Kersten S. Rabe et al. CHEMBIOCHEM
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now