The Structure of a Transient Complex of a Nonribosomal Peptide Synthetase and a Cytochrome P450 Monooxygenase

Stereochemistry and Conformation of Skyllamycin, a Non-Ribosomally Synthesized Peptide fromStreptomycessp. Acta 2897

(2014) Vivien Schubert et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cytochrome P450sky Interacts Directly with the Nonribosomal Peptide Synthetase to Generate Three Amino Acid Precursors in Skyllamycin Biosynthesis

(2013) Stefanie Uhlmann et al.   ACS Chemical Biology

Combating Multidrug-Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials

(2013) Kieron M. G. O'Connell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis

(2013) Lijiang Song et al.   JOURNAL OF ANTIBIOTICS

Binding of a Cyano- and Fluoro-containing Drug Bicalutamide to Cytochrome P450 46A1

(2013) Natalia Mast et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptation of Aminoacyl-tRNA Synthetase Catalytic Core to Carrier Protein Aminoacylation

(2013) Marko Mocibob et al.   STRUCTURE

Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains

(2012) Jesse A. Sundlov et al.   CHEMISTRY & BIOLOGY

The structural role of the carrier protein – active controller or passive carrier

(2012) John Crosby et al.   NATURAL PRODUCT REPORTS

Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology

(2012) Gene H. Hur et al.   NATURAL PRODUCT REPORTS

Structural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide Synthetases

(2011) Ye Liu et al.   CHEMISTRY & BIOLOGY

Biosynthetic Gene Cluster of the Non-ribosomally Synthesized Cyclodepsipeptide Skyllamycin: Deciphering Unprecedented Ways of Unusual Hydroxylation Reactions

(2011) Stefan Pohle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Characterization of OxyD, a Cytochrome P450 Involved in β-Hydroxytyrosine Formation in Vancomycin Biosynthesis

(2010) Max J. Cryle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450BioI ACP complex

(2008) M. J. Cryle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Screening of fusion partners for high yield expression and purification of bioactive viscotoxins

(2008) Julius Bogomolovas et al.   PROTEIN EXPRESSION AND PURIFICATION

Structural characterization of CalO2: A putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway

(2008) Jason G. McCoy et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase

(2008) A. Tanovic et al.   SCIENCE