Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis

Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products

(2015) Rashed S. Al Toma et al.   NATURAL PRODUCT REPORTS

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

(2015) Kristina Haslinger et al.   NATURE

Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics

(2015) Clara Brieke et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structure of the terminal PCP domain of the non-ribosomal peptide synthetase in teicoplanin biosynthesis

(2015) Kristina Haslinger et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Highly Selective but Multifunctional Oxygenases in Secondary Metabolism

(2014) Rachel V. K. Cochrane et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Structure of a Transient Complex of a Nonribosomal Peptide Synthetase and a Cytochrome P450 Monooxygenase

(2014) Kristina Haslinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cytochrome P450 OxyBteiCatalyzes the First Phenolic Coupling Step in Teicoplanin Biosynthesis

(2014) Kristina Haslinger et al.   CHEMBIOCHEM

Generation of Complexity in Fungal Terpene Biosynthesis: Discovery of a Multifunctional Cytochrome P450 in the Fumagillin Pathway

(2014) Hsiao-Ching Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Facile Fmoc Solid Phase Synthesis Strategy To Access Epimerization-Prone Biosynthetic Intermediates of Glycopeptide Antibiotics

(2014) Clara Brieke et al.   ORGANIC LETTERS

Complexity Generation in Fungal Polyketide Biosynthesis: A Spirocycle-Forming P450 in the Concise Pathway to the Antifungal Drug Griseofulvin

(2013) Ralph A. Cacho et al.   ACS Chemical Biology

Cytochrome P450sky Interacts Directly with the Nonribosomal Peptide Synthetase to Generate Three Amino Acid Precursors in Skyllamycin Biosynthesis

(2013) Stefanie Uhlmann et al.   ACS Chemical Biology

Nonproteinogenic Amino Acid Building Blocks for Nonribosomal Peptide and Hybrid Polyketide Scaffolds

(2013) Christopher T. Walsh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycopeptide antibiotic biosynthesis

(2013) Grace Yim et al.   JOURNAL OF ANTIBIOTICS

A Cytochrome P450 Serves as an Unexpected Terpene Cyclase during Fungal Meroterpenoid Biosynthesis

(2013) Yit-Heng Chooi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Substituent Effects on the Phenol Coupling Reaction Catalyzed by the Vancomycin Biosynthetic P450 Enzyme OxyB

(2012) Patrick C. Schmartz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nucleophilic Reactivities of Hydrazines and Amines: The Futile Search for the α-Effect in Hydrazine Reactivities

(2012) Tobias A. Nigst et al.   JOURNAL OF ORGANIC CHEMISTRY

Diversity of P450 enzymes in the biosynthesis of natural products

(2012) Larissa M. Podust et al.   NATURAL PRODUCT REPORTS

Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology

(2012) Gene H. Hur et al.   NATURAL PRODUCT REPORTS

Carrier protein substrates in cytochrome P450-catalysed oxidation

(2011) Max J. Cryle   Metallomics

Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system

(2011) N. Strushkevich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Characterization of OxyD, a Cytochrome P450 Involved in β-Hydroxytyrosine Formation in Vancomycin Biosynthesis

(2010) Max J. Cryle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450BioI ACP complex

(2008) M. J. Cryle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA