Unusual Cytochrome P450 Enzymes and Reactions

Reactive Intermediates in Cytochrome P450 Catalysis

(2013) Courtney M. Krest et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unusual properties of the cytochrome P450 superfamily

(2013) D. C. Lamb et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Involvement of a Natural Fusion of a Cytochrome P450 and a Hydrolase in Mycophenolic Acid Biosynthesis

(2012) Bjarne Gram Hansen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A Gene-Fusion Approach to Enabling Plant Cytochromes P450 for Biocatalysis

(2012) Julia Schückel et al.   CHEMBIOCHEM

Bioactivation of Fluorinated 2-Aryl-benzothiazole Antitumor Molecules by Human Cytochrome P450s 1A1 and 2W1 and Deactivation by Cytochrome P450 2S1

(2012) Kai Wang et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Reactive Intermediates Produced from the Metabolism of the Vanilloid Ring of Capsaicinoids by P450 Enzymes

(2012) Christopher A. Reilly et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Contributions of Human Enzymes in Carcinogen Metabolism

(2012) Slobodan Rendic et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Biotransformation of BDE-47 to Potentially Toxic Metabolites Is Predominantly Mediated by Human CYP2B6

(2012) Maria Luisa Feo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Characterization of Cupriavidus metallidurans CYP116B1 - A thiocarbamate herbicide oxygenating P450-phthalate dioxygenase reductase fusion protein

(2012) Ashley J. Warman et al.   FEBS Journal

Unusual Spectroscopic and Ligand Binding Properties of the Cytochrome P450-Flavodoxin Fusion Enzyme XplA

(2012) Soi H. Bui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolism of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine by Mitochondrion-targeted Cytochrome P450 2D6

(2012) Prachi Bajpai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proximal Ligand Electron Donation and Reactivity of the Cytochrome P450 Ferric–Peroxo Anion

(2012) Santhosh Sivaramakrishnan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

(2012) Sarah M Barry et al.   Nature Chemical Biology

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

(2012) P. S. Coelho et al.   SCIENCE

Use of Perfluorocarboxylic Acids To Trick Cytochrome P450BM3 into Initiating the Hydroxylation of Gaseous Alkanes

(2011) Norifumi Kawakami et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tuning a P450 Enzyme for Methane Oxidation

(2011) Felipe E. Zilly et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Terminal Olefin (1-Alkene) Biosynthesis by a Novel P450 Fatty Acid Decarboxylase fromJeotgalicoccusSpecies

(2011) Mathew A. Rude et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cytochrome P450 2S1 is Reduced by NADPH-Cytochrome P450 Reductase

(2011) Y. Xiao et al.   DRUG METABOLISM AND DISPOSITION

Oxylipins in fungi

(2011) Florian Brodhun et al.   FEBS Journal

Conversion of 7-Dehydrocholesterol to 7-Ketocholesterol Is Catalyzed by Human Cytochrome P450 7A1 and Occurs by Direct Oxidation without an Epoxide Intermediate

(2011) Raku Shinkyo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of H2O2-dependent Cytochrome P450SPαwith Its Bound Fatty Acid Substrate

(2011) Takashi Fujishiro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the Glycosyltransferase EryCIII in Complex with its Activating P450 Homologue EryCII

(2011) Martin C. Moncrieffe et al.   JOURNAL OF MOLECULAR BIOLOGY

Regio- and stereoselectivity of P450-catalysed hydroxylation of steroids controlled by laboratory evolution

(2011) Sabrina Kille et al.   Nature Chemistry

Molecular probes of the mechanism of cytochrome P450. Oxygen traps a substrate radical intermediate

(2010) Harriet L.R. Cooper et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: Implications for the mechanism of electron transfer in the P450 BM3 dimer

(2010) Hazel M. Girvan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The explosive-degrading cytochrome P450 XplA: Biochemistry, structural features and prospects for bioremediation

(2010) Elizabeth L. Rylott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cloning, Expression and Purification of Cindoxin, an Unusual Fmn-Containing Cytochrome P450 Redox Partner

(2010) David B. Hawkes et al.   CHEMBIOCHEM

Mechanistic Studies on a P450-Mediated Rearrangement of BMS-690514: Conversion of a Pyrrolotriazine to a Hydroxypyridotriazine†

(2010) Haizheng Hong et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Cyclization of a Cellular Dipentaenone byStreptomyces coelicolorCytochrome P450 154A1 without Oxidation/Reduction

(2010) Qian Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Hypoxic Activation of the Anticancer Agent AQ4N by CYP2S1 and CYP2W1

(2010) C. R. Nishida et al.   MOLECULAR PHARMACOLOGY

Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics

(2010) J. Rittle et al.   SCIENCE

A Predominate Role of CYP1A2 for the Metabolism of Nabumetone to the Active Metabolite, 6-Methoxy-2-naphthylacetic Acid, in Human Liver Microsomes

(2009) M. Turpeinen et al.   DRUG METABOLISM AND DISPOSITION

CYP719B1 Is Salutaridine Synthase, the C-C Phenol-coupling Enzyme of Morphine Biosynthesis in Opium Poppy

(2009) Andreas Gesell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Cytochrome P450 Enzymes Catalyze the Phenol-coupling Step in Endogenous Morphine Biosynthesis

(2009) Nadja Grobe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of PpoA fromAspergillus nidulansas a Fusion Protein of a Fatty Acid Heme Dioxygenase/Peroxidase and a Cytochrome P450

(2009) Florian Brodhun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site

(2009) Bin Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The First Virally Encoded Cytochrome P450

(2009) D. C. Lamb et al.   JOURNAL OF VIROLOGY

Mechanistic aspects of CYP74 allene oxide synthases and related cytochrome P450 enzymes

(2009) Alan R. Brash   PHYTOCHEMISTRY

Molecular Cloning and Characterization of CYP80G2, a Cytochrome P450 That Catalyzes an Intramolecular C–C Phenol Coupling of (S)-Reticuline in Magnoflorine Biosynthesis, from CulturedCoptis japonicaCells

(2008) Nobuhiro Ikezawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CYP719A subfamily of cytochrome P450 oxygenases and isoquinoline alkaloid biosynthesis in Eschscholzia californica

(2008) Nobuhiro Ikezawa et al.   PLANT CELL REPORTS