Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology

Directed Evolution of a Gatekeeper Domain in Nonribosomal Peptide Synthesis

(2011) Benoit Villiers et al.   CHEMISTRY & BIOLOGY

Function of MbtH homologs in nonribosomal peptide biosynthesis and applications in secondary metabolite discovery

(2011) Richard H. Baltz   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity

(2011) Marc Röttig et al.   NUCLEIC ACIDS RESEARCH

MbtH-Like Proteins as Integral Components of Bacterial Nonribosomal Peptide Synthetases

(2010) Elizabeth A. Felnagle et al.   BIOCHEMISTRY

Functional Dissection of Surfactin Synthetase Initiation Module Reveals Insights into the Mechanism of Lipoinitiation

(2010) Femke I. Kraas et al.   CHEMISTRY & BIOLOGY

N-Acylation during Glidobactin Biosynthesis by the Tridomain Nonribosomal Peptide Synthetase Module GlbF

(2010) Heidi J. Imker et al.   CHEMISTRY & BIOLOGY

Nonribosomal peptide synthetases: structures and dynamics

(2010) Matthias Strieker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases

(2010) Joachim Zettler et al.   FEBS Journal

Diversity of Nonribosomal Peptide Synthetases Involved in the Biosynthesis of Lipopeptide Biosurfactants

(2010) Niran Roongsawang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Activity-guided engineering of natural product carrier proteins

(2010) Andrew S. Worthington et al.   Molecular BioSystems

Solution structure of Rv2377c-founding member of the MbtH-like protein family

(2010) Garry W. Buchko et al.   TUBERCULOSIS

Mapping the Limits of Substrate Specificity of the Adenylation Domain of TycA

(2009) Benoit R. M. Villiers et al.   CHEMBIOCHEM

Structure and Function of the Glycopeptide N-methyltransferase MtfA, a Tool for the Biosynthesis of Modified Glycopeptide Antibiotics

(2009) Rong Shi et al.   CHEMISTRY & BIOLOGY

Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis

(2009) Gene H. Hur et al.   CHEMISTRY & BIOLOGY

TioS T-TE - a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides

(2009) Lars Robbel et al.   FEBS Journal

Structure of a Eukaryotic Nonribosomal Peptide Synthetase Adenylation Domain That Activates a Large Hydroxamate Amino Acid in Siderophore Biosynthesis

(2009) T. Verne Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Bacillus cereus d-Alanyl Carrier Protein Ligase (DltA) in Complex with ATP

(2009) Khan Tanjid Osman et al.   JOURNAL OF MOLECULAR BIOLOGY

Working outside the protein-synthesis rules: insights into non-ribosomal peptide synthesis

(2009) Mohamed A. Marahiel   JOURNAL OF PEPTIDE SCIENCE

Enzymatic Tailoring of Ornithine in the Biosynthesis of theRhizobiumCyclic Trihydroxamate Siderophore Vicibactin

(2009) John R. Heemstra et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Analysis of an Open Active Site Conformation of Nonheme Iron Halogenase CytC3

(2009) Cintyu Wong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural insights into nonribosomal peptide enzymatic assembly lines

(2009) Alexander Koglin et al.   NATURAL PRODUCT REPORTS

Computational structure-based redesign of enzyme activity

(2009) C.-Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis

(2009) S. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalytic mechanisms, basic roles, and biotechnological and environmental significance of halogenating enzymes

(2008) Xianping Chen et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Three Thioesterases Are Involved in the Biosynthesis of Phosphinothricin Tripeptide in Streptomyces viridochromogenes Tu494

(2008) S. Eys et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Crystal Structure and Enantiomer Selection byd-Alanyl Carrier Protein Ligase DltA fromBacillus cereus†

(2008) Liqin Du et al.   BIOCHEMISTRY

Tandem heterocyclization domains in a nonribosomal peptide synthetase essential for siderophore biosynthesis in Vibrio anguillarum

(2008) Manuela Di Lorenzo et al.   BIOMETALS

Effect of Fengycin, a Lipopeptide Produced by Bacillus subtilis, on Model Biomembranes

(2008) Magali Deleu et al.   BIOPHYSICAL JOURNAL

Nonribosomal Biosynthesis of Fusaricidins by Paenibacillus polymyxa PKB1 Involves Direct Activation of a d-Amino Acid

(2008) Jingru Li et al.   CHEMISTRY & BIOLOGY

Role of DptE and DptF in the lipidation reaction of daptomycin

(2008) Melanie Wittmann et al.   FEBS Journal

Structure and Functional Analysis of RifR, the Type II Thioesterase from the Rifamycin Biosynthetic Pathway

(2008) Heather B. Claxton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of DltA

(2008) Huma Yonus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Action of the Myxobacterial Chondrochloren Halogenase CndH: A New Variant of FAD-dependent Halogenases

(2008) Stefan Buedenbender et al.   JOURNAL OF MOLECULAR BIOLOGY

Myxochelin Biosynthesis: Direct Evidence for Two- and Four-Electron Reduction of a Carrier Protein-Bound Thioester

(2008) Yanyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of the nonribosomal peptide synthetase gene responsible for bassianolide synthesis in wood-decaying fungus Xylaria sp. BCC1067

(2008) J. Jirakkakul et al.   MICROBIOLOGY-SGM

Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase

(2008) Dominique P. Frueh et al.   NATURE

Structural basis for the selectivity of the external thioesterase of the surfactin synthetase

(2008) Alexander Koglin et al.   NATURE

Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase

(2008) A. Tanovic et al.   SCIENCE