- Home
- Publications
- Publication Search
- Publication Details
Title
Are immunotherapies for Huntington’s disease a realistic option?
Authors
Keywords
-
Journal
MOLECULAR PSYCHIATRY
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-02-28
DOI
10.1038/s41380-018-0021-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis
- (2017) Danfeng Xu et al. Journal of Neuroinflammation
- Laquinimod treatment in the R6/2 mouse model
- (2017) Gisa Ellrichmann et al. Scientific Reports
- Human-to-mouse prion-like propagation of mutant huntingtin protein
- (2016) Iksoo Jeon et al. ACTA NEUROPATHOLOGICA
- Epigallocatechin gallate attenuates amyloid β-induced inflammation and neurotoxicity in EOC 13.31 microglia
- (2016) James Cheng-Chung Wei et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease
- (2016) Juan Carlos Corona et al. FREE RADICAL BIOLOGY AND MEDICINE
- Laquinimod dampens hyperactive cytokine production in Huntington's disease patient myeloid cells
- (2016) Lucianne Dobson et al. JOURNAL OF NEUROCHEMISTRY
- A double-blind, randomized, cross-over, placebo-controlled, pilot trial with Sativex in Huntington’s disease
- (2016) Jose Luis López-Sendón Moreno et al. JOURNAL OF NEUROLOGY
- VCE-003.2, a novel cannabigerol derivative, enhances neuronal progenitor cell survival and alleviates symptomatology in murine models of Huntington’s disease
- (2016) Javier Díaz-Alonso et al. Scientific Reports
- Targeting Cannabinoid CB2 Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders
- (2016) Gemma Navarro et al. Frontiers in Neuroscience
- Antibodies inside of a cell can change its outside: Can intrabodies provide a new therapeutic paradigm?
- (2016) Andrea L.J. Marschall et al. Computational and Structural Biotechnology Journal
- Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
- (2016) Marta Garcia-Miralles et al. Scientific Reports
- Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
- (2015) Javier Egea et al. BIOCHEMICAL PHARMACOLOGY
- The role of tau in the pathological process and clinical expression of Huntington’s disease
- (2015) Romina Vuono et al. BRAIN
- The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway
- (2015) C Blázquez et al. CELL DEATH AND DIFFERENTIATION
- Transcriptional dysregulation of inflammatory/immune pathways after active vaccination against Huntington′s disease
- (2015) Arlene I. Ramsingh et al. HUMAN MOLECULAR GENETICS
- Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington’s disease patients
- (2015) Edward J. Wild et al. JOURNAL OF CLINICAL INVESTIGATION
- Treating the whole body in Huntington's disease
- (2015) Jeffrey B Carroll et al. LANCET NEUROLOGY
- PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically
- (2015) Audrey S Dickey et al. NATURE MEDICINE
- Epigallocatechin-3-gallate treatment to promote neuroprotection and functional recovery after nervous system injury
- (2015) Pere Boadas-Vaello et al. Neural Regeneration Research
- SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease
- (2015) Ernest S. Smith et al. NEUROBIOLOGY OF DISEASE
- Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease
- (2015) Amber L. Southwell et al. NEUROBIOLOGY OF DISEASE
- The choreography of neuroinflammation in Huntington's disease
- (2015) Andrea Crotti et al. TRENDS IN IMMUNOLOGY
- HTT-lowering reverses Huntington’s disease immune dysfunction caused by NFκB pathway dysregulation
- (2014) Ulrike Träger et al. BRAIN
- The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios
- (2014) Heike J. Wobst et al. FEBS LETTERS
- Dexamethasone induces heat shock response and slows down disease progression in mouse and fly models of Huntington's disease
- (2014) M. Maheshwari et al. HUMAN MOLECULAR GENETICS
- Tau hyperphosphorylation and deregulation of calcineurin in mouse models of Huntington's disease
- (2014) Maud Gratuze et al. HUMAN MOLECULAR GENETICS
- Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease
- (2014) Han-Yun Hsiao et al. HUMAN MOLECULAR GENETICS
- Cannabinoid receptor CB2 is expressed on vascular cells, but not astroglial cells in the post-mortem human Huntington's disease brain
- (2014) Megan J. Dowie et al. JOURNAL OF CHEMICAL NEUROANATOMY
- AAV-Dominant Negative Tumor Necrosis Factor (DN-TNF) Gene Transfer to the Striatum Does Not Rescue Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease
- (2014) Laura Taylor Alto et al. PLoS One
- A Cannabigerol Derivative Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis
- (2014) Francisco J. Carrillo-Salinas et al. PLoS One
- Reduction in Cerebral Atrophy Associated with Ethyl-Eicosapentaenoic Acid Treatment in Patients with Huntington's Disease
- (2013) BK Puri et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington's Disease
- (2013) D. A. Simmons et al. JOURNAL OF NEUROSCIENCE
- Dose-dependent Neuroprotection of VEGF165 in Huntington's Disease Striatum
- (2013) Stuart M Ellison et al. MOLECULAR THERAPY
- Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease
- (2013) Frank M. Longo et al. NATURE REVIEWS DRUG DISCOVERY
- Intrabodies as Neuroprotective Therapeutics
- (2013) Anne Messer et al. Neurotherapeutics
- Sativex-like Combination of Phytocannabinoids is Neuroprotective in Malonate-Lesioned Rats, an Inflammatory Model of Huntington’s Disease: Role of CB1 and CB2 Receptors
- (2012) Sara Valdeolivas et al. ACS Chemical Neuroscience
- Mutant huntingtin impairs immune cell migration in Huntington disease
- (2012) Wanda Kwan et al. JOURNAL OF CLINICAL INVESTIGATION
- A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis
- (2012) Aitor G. Granja et al. Journal of Neuroimmune Pharmacology
- Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease
- (2012) W. Kwan et al. JOURNAL OF NEUROSCIENCE
- Cannabinoid Receptor 2 Signaling in Peripheral Immune Cells Modulates Disease Onset and Severity in Mouse Models of Huntington's Disease
- (2012) J. Bouchard et al. JOURNAL OF NEUROSCIENCE
- Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis
- (2012) Giancarlo Comi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Impaired Heat Shock Response in Cells Expressing Full-Length Polyglutamine-Expanded Huntingtin
- (2012) Sidhartha M. Chafekar et al. PLoS One
- Plant polyphenols attenuate hepatic injury after hemorrhage/resuscitation by inhibition of apoptosis, oxidative stress, and inflammation via NF-kappaB in rats
- (2011) Borna Relja et al. EUROPEAN JOURNAL OF NUTRITION
- Laquinimod: a promising oral medication for the treatment of relapsing-remitting multiple sclerosis
- (2011) Jan Thöne et al. Expert Opinion on Drug Metabolism & Toxicology
- Insight into the mechanism of laquinimod action
- (2011) W. Brück et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- The role of immunity in Huntington's disease
- (2011) D Soulet et al. MOLECULAR PSYCHIATRY
- Bifunctional Anti-Huntingtin Proteasome-Directed Intrabodies Mediate Efficient Degradation of Mutant Huntingtin Exon 1 Protein Fragments
- (2011) David C. Butler et al. PLoS One
- Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study
- (2010) Marios Politis et al. HUMAN BRAIN MAPPING
- Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
- (2010) Stephen M. Massa et al. JOURNAL OF CLINICAL INVESTIGATION
- Early or Late-Stage Anti-N-Terminal Huntingtin Intrabody Gene Therapy Reduces Pathological Features in B6.HDR6/1 Mice
- (2010) Abigail Snyder-Keller et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- A futility study of minocycline in Huntington's disease
- (2010) Merit Cudkowicz MOVEMENT DISORDERS
- Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice
- (2010) M.J. Dowie et al. NEUROSCIENCE
- Dual Beneficial Effects of (-)-Epigallocatechin-3-Gallate on Levodopa Methylation and Hippocampal Neurodegeneration: In Vitro and In Vivo Studies
- (2010) Ki Sung Kang et al. PLoS One
- Cannabinoid CB2receptor agonists protect the striatum against malonate toxicity: Relevance for Huntington's disease
- (2009) Onintza Sagredo et al. GLIA
- Rrs1 Is Involved in Endoplasmic Reticulum Stress Response in Huntington Disease
- (2009) Alisia Carnemolla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Roles of Sema4D-Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis
- (2009) T. Okuno et al. JOURNAL OF IMMUNOLOGY
- Intrabody Gene Therapy Ameliorates Motor, Cognitive, and Neuropathological Symptoms in Multiple Mouse Models of Huntington's Disease
- (2009) A. L. Southwell et al. JOURNAL OF NEUROSCIENCE
- Beyond the brain: widespread pathology in Huntington's disease
- (2009) Jorien MM van der Burg et al. LANCET NEUROLOGY
- A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
- (2008) Maria Björkqvist et al. JOURNAL OF EXPERIMENTAL MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now