AAV-Dominant Negative Tumor Necrosis Factor (DN-TNF) Gene Transfer to the Striatum Does Not Rescue Medium Spiny Neurons in the YAC128 Mouse Model of Huntington's Disease

Mutant huntingtin impairs immune cell migration in Huntington disease

(2012) Wanda Kwan et al.   JOURNAL OF CLINICAL INVESTIGATION

Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease

(2012) W. Kwan et al.   JOURNAL OF NEUROSCIENCE

Huntington’s Disease and the Striatal Medium Spiny Neuron: Cell-Autonomous and Non-Cell-Autonomous Mechanisms of Disease

(2012) Michelle E. Ehrlich   Neurotherapeutics

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

(2011) Roberta Brambilla et al.   BRAIN

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease

(2011) Sonia Franciosi et al.   NEUROBIOLOGY OF DISEASE

Enhanced Th17-Cell Responses Render CCR2-Deficient Mice More Susceptible for Autoimmune Arthritis

(2011) Rishi R. Rampersad et al.   PLoS One

Contribution of systemic inflammation to chronic neurodegeneration

(2010) V. Hugh Perry   ACTA NEUROPATHOLOGICA

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study

(2010) Marios Politis et al.   HUMAN BRAIN MAPPING

Neuroinflammation in Huntington’s disease

(2010) Thomas Möller   JOURNAL OF NEURAL TRANSMISSION

Delayed Dominant-Negative TNF Gene Therapy Halts Progressive Loss of Nigral Dopaminergic Neurons in a Rat Model of Parkinson's Disease

(2010) Ashley S Harms et al.   MOLECULAR THERAPY

Inflammation in transgenic mouse models of neurodegenerative disorders

(2009) Claudia Schwab et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

(2009) Leslie Michels Thompson et al.   JOURNAL OF CELL BIOLOGY

Neuroprotective Effects of Inositol 1,4,5-Trisphosphate Receptor C-Terminal Fragment in a Huntington's Disease Mouse Model

(2009) T.-S. Tang et al.   JOURNAL OF NEUROSCIENCE

Does neuroinflammation fan the flame in neurodegenerative diseases?

(2009) Tamy C Frank-Cannon et al.   Molecular Neurodegeneration

Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology

(2009) Fiona E. McAlpine et al.   NEUROBIOLOGY OF DISEASE

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

(2009) Liliana Menalled et al.   NEUROBIOLOGY OF DISEASE

Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?

(2009) Kurt M. Lucin et al.   NEURON

Distinct neuroinflammatory profile in post-mortem human Huntingtonʼs disease

(2009) Aurelio Silvestroni et al.   NEUROREPORT

Minocycline and neurodegenerative diseases

(2008) Hye-Sun Kim et al.   BEHAVIOURAL BRAIN RESEARCH

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction of chemokines, MCP-1, and KC in the mutant huntingtin expressing neuronal cells because of proteasomal dysfunction

(2008) Swetha K. Godavarthi et al.   JOURNAL OF NEUROCHEMISTRY

Expanded-Polyglutamine Huntingtin Protein Suppresses the Secretion and Production of a Chemokine (CCL5/RANTES) by Astrocytes

(2008) S.-Y. Chou et al.   JOURNAL OF NEUROSCIENCE

Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats

(2008) Melissa K McCoy et al.   MOLECULAR THERAPY

Striosome-matrix pathology and motor deficits in the YAC128 mouse model of Huntington's disease

(2008) Collene Lawhorn et al.   NEUROBIOLOGY OF DISEASE

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

(2008) Hui-Ming Gao et al.   TRENDS IN IMMUNOLOGY