Mutant huntingtin impairs immune cell migration in Huntington disease

The Wiskott-Aldrich Syndrome: The Actin Cytoskeleton and Immune Cell Function

(2013) Michael P. Blundell et al.   DISEASE MARKERS

Bone Marrow Transplantation Confers Modest Benefits in Mouse Models of Huntington's Disease

(2012) W. Kwan et al.   JOURNAL OF NEUROSCIENCE

Kynurenine 3-Monooxygenase Inhibition in Blood Ameliorates Neurodegeneration

(2011) Daniel Zwilling et al.   CELL

Mutant Huntingtin Causes Metabolic Imbalance by Disruption of Hypothalamic Neurocircuits

(2011) Sofia Hult et al.   Cell Metabolism

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

(2011) Lise Munsie et al.   HUMAN MOLECULAR GENETICS

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis

(2011) Surya A. Reis et al.   HUMAN MOLECULAR GENETICS

CX3CR1 Deficiency Leads to Impairment of Hippocampal Cognitive Function and Synaptic Plasticity

(2011) J. T. Rogers et al.   JOURNAL OF NEUROSCIENCE

Enhanced Th17-Cell Responses Render CCR2-Deficient Mice More Susceptible for Autoimmune Arthritis

(2011) Rishi R. Rampersad et al.   PLoS One

Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

(2011) O. Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deficiency of Huntingtin Has Pleiotropic Effects in the Social Amoeba Dictyostelium discoideum

(2011) Michael A. Myre et al.   PLoS Genetics

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study

(2010) Marios Politis et al.   HUMAN BRAIN MAPPING

The myeloid cells of the central nervous system parenchyma

(2010) Richard M. Ransohoff et al.   NATURE

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

Huntington's disease: The current state of research with peripheral tissues

(2009) Jenny Sassone et al.   EXPERIMENTAL NEUROLOGY

Resting Microglia Directly Monitor the Functional State of Synapses In Vivo and Determine the Fate of Ischemic Terminals

(2009) H. Wake et al.   JOURNAL OF NEUROSCIENCE

Beyond the brain: widespread pathology in Huntington's disease

(2009) Jorien MM van der Burg et al.   LANCET NEUROLOGY

Microglial cell migration stimulated by ATP and C5a involve distinct molecular mechanisms: Quantification of migration by a novel near-infrared method

(2008) Aaron M. Miller et al.   GLIA

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

(2008) M. Gray et al.   JOURNAL OF NEUROSCIENCE

Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia

(2008) Yasuhiro Irino et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease

(2008) Caroline L Benn et al.   Molecular Neurodegeneration

Weight loss in Huntington disease increases with higher CAG repeat number

(2008) N. A. Aziz et al.   NEUROLOGY

Chromosomal profiles of gene expression in Huntington's disease

(2007) A. N. Anderson et al.   BRAIN