Impaired Heat Shock Response in Cells Expressing Full-Length Polyglutamine-Expanded Huntingtin

Polyglutamine misfolding in yeast: Toxic and protective aggregation

(2012) Martin L. Duennwald   Prion

Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease

(2011) John Labbadia et al.   JOURNAL OF CLINICAL INVESTIGATION

Small-molecule proteostasis regulators for protein conformational diseases

(2011) Barbara Calamini et al.   Nature Chemical Biology

Huntington's Disease

(2011) S. Finkbeiner   Cold Spring Harbor Perspectives in Biology

Modeling general proteostasis: proteome balance in health and disease

(2010) Daniela M Roth et al.   CURRENT OPINION IN CELL BIOLOGY

Analysis of Chaperone mRNA Expression in the Adult Mouse Brain by Meta Analysis of the Allen Brain Atlas

(2010) Andrew T. N. Tebbenkamp et al.   PLoS One

Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease

(2010) Daniel W. Neef et al.   PLOS BIOLOGY

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

(2008) M. L. Duennwald et al.   GENES & DEVELOPMENT

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

The Ubiquitin-Proteasome Pathway in Huntington's Disease

(2008) Siddhartha Mitra et al.   TheScientificWorldJOURNAL